The Ligandable Human Proteome

Home

Peroxisome proliferator-activated receptor gamma

Nuclear hormone receptor, ligand-binding domain

IndexLigand NameStructurePDB codeCompound Potency nM
1570THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES.1fm91
2nsiCrystal Structure of PPAR Gamma with N-sulfonyl-2-indole carboxamide ligands2hfp3
3untX-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist3ia63
4zaaX-ray crystal structure of human ppar gamma with 2-(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-2-phenyl-2h-1,2,3-triazol-4-yl)acetic acid3bc55
57mvPeroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selectively PPAR gamma-modulating ligand VSP-515two8.06
6ro7Aleglitaar. a new. potent, and balanced dual ppara/g agonist for the treatment of type II diabetes3g9e19
7ehaCrystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist2f4b50
8drfLigand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist1nyx92
93eaCrystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist2ath152
10l92X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist2q8s185
11az2CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST AZ 2421i7i200
12c01Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist1zeo210
13208Structure-based Design of Indole Propionic Acids as Novel PPARag CO-Agonists2gtk251
143e7Crystal Structure of SR2067 bound to PPARgamma4r06513
15drjCrystal structure of the complex between PPARgamma and the agonist LT160 (ureidofibrate derivative)2i4j684.8
16ctmDesign and biological evaluation of novel, balanced dual PPARa/g agonists3fej740
17sfiPPARgamma ligand binding domain in complex with sulindac sulfide4xuh1870
18drhCrystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). Structure obtained from crystals of the apo-form soaked for 30 days.2i4p1978
19drhCrystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). This structure has been obtained from crystals soaked for 6 hours.2i4z1978
20xcxCrystal Structure of PPARgamma with an achiral ureidofibrate derivative (RT86)3r8i4500
21imnHuman PPARgamma ligand-binding domain in complex with indomethacin3ads9730
227vaX-ray Crystal Structure of the PPARgamma Ligand Binding Domain in Complex with Rivoglitazone5u5l1.4e+004
23imnPPARgamma ligand binding domain in complex with indomethacin4xum2.13e+004