The Ligandable Human Proteome

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NAD-dependent protein deacetylase sirtuin-2

Sirtuin family

IndexLigand NameStructurePDB codeCompound Potency nM
15grCrystal structure of human Sirt2 in complex with a SirReal probe fragment5dy5163
27kjStructure of human Sirtuin 2 in complex with a selective thienopyrimidinone based inhibitor5mat580
38noCrystal structure of human Sirtuin 2 in complex with a selective inhibitor5y5n1740