The Ligandable Human Proteome

Home

Cellular tumor antigen p53

p53, DNA-binding domain

IndexLigand NameStructurePDB codeCompound Potency nM
192oStructure of the p53 cancer mutant Y220C with bound small molecule 7- ethyl-3-(piperidin-4-yl)-1H-indole5ab9470
2p96Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51964agq9700
3p74Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51744ago1.55e+004
4p51Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51764agp2.06e+004
5y0vStructure of the p53 cancer mutant Y220C in complex with 2-hydroxy-3, 5-diiodo-4-(1H-pyrrol-1-yl)benzoic acid5aoj2.1e+004
6p86Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan50864agm1.05e+005
7nxgStructure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51164agn1.07e+005
8p84Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan7844agl2.25e+005
9kmnStructure of the p53 cancer Y220C bound to the stabilizing small molecule PhiKan52115a7b2.71e+005
10ul7Structure of the p53 cancer mutant Y220C with bound small-molecule stabilizer PhiKan51495aba1.04e+006
11fy8Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan8835aom1.27e+006