The Ligandable Human Proteome

Cytochrome P450

Index	Ligand Name	Gene Name Primary	Protein Name	Uniprot ID	Gene Name Synonym	PDB Codes
1	1ca	C11B2	Cytochrome P450 11B2, mitochondrial	P19099		4dvq
2	hcd	CP11A	Cholesterol side-chain cleavage enzyme, mitochondrial	P05108	CYP11A	3na1
3	hc9	CP11A	Cholesterol side-chain cleavage enzyme, mitochondrial	P05108	CYP11A	3n9z
4	clr	CP11A	Cholesterol side-chain cleavage enzyme, mitochondrial	P05108	CYP11A	3n9y
5	2dc	CP11A	Cholesterol side-chain cleavage enzyme, mitochondrial	P05108	CYP11A	3na0
6	tok	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	3swz
7	aer	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	3ruk, 4nkv
8	8qd	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	5uys
9	3nr	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	6ciz
10	3nq	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	6cir
11	plo	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	4nkw
12	3qz	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	4nky
13	6d7	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	5irq
14	3nx	CP17A	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	6chi
15	str	CP17A,CP21A,CP3A4	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	CYP17 S17AH	1w0f, 4nkx, 4y8w, 5a1p, 5a1r
16	tes	CP19A	Aromatase	P11511	ARO1 CYAR CYP19	5jkw
17	asd	CP19A	Aromatase	P11511	ARO1 CYAR CYP19	3eqm, 3s79, 5jkv, 5jl6
18	hjj	CP1A1	Cytochrome P450 1A1	P04798		6dwm
19	aq4	CP1A1	Cytochrome P450 1A1	P04798		6dwn
20	d1g	CP2A6	Cytochrome P450 2A6	P11509	CYP2A3	2fdu
21	9pl	CP2A6,CP2AD,CP2E1	Cytochrome P450 2E1	P05181	CYP2E	3t3q, 3t3r, 3t3s, 3t3z
22	0qa	CP2AD	Cytochrome P450 2A13	Q16696		4ejh, 4eji
23	mtk	CP2C8	Cytochrome P450 2C8	P10632		2nni
24	9cr	CP2C8	Cytochrome P450 2C8	P10632		2nnh
25	225	CP2C8	Cytochrome P450 2C8	P10632		2nnj
26	tdz	CP2C8	Cytochrome P450 2C8	P10632		2vn0
27	flp	CP2C9	Cytochrome P450 2C9	P11712	CYP2C10	1r9o
28	lsn	CP2C9	Cytochrome P450 2C9	P11712	CYP2C10	5x24
29	9w6	CP2C9	Cytochrome P450 2C9	P11712	CYP2C10	5w0c
30	swf	CP2C9	Cytochrome P450 2C9	P11712	CYP2C10	1og5
31	pn0	CP2D6	Cytochrome P450 2D6	P10635	CYP2DL1	3qm4, 3tda, 6csd
32	qi9	CP2D6	Cytochrome P450 2D6	P10635	CYP2DL1	4wnv
33	si6	CP2D6	Cytochrome P450 2D6	P10635	CYP2DL1	4xrz
34	si5	CP2D6	Cytochrome P450 2D6	P10635	CYP2DL1	4xry
35	p6m	CP2D6	Cytochrome P450 2D6	P10635	CYP2DL1	5tfu
36	p6u	CP2D6	Cytochrome P450 2D6	P10635	CYP2DL1	5tft
37	qdn	CP2D6	Cytochrome P450 2D6	P10635	CYP2DL1	4wnu
38	vd3	CP2R1	Vitamin D 25-hydroxylase	Q6VVX0		3c6g
39	v2h	CP2R1	Vitamin D 25-hydroxylase	Q6VVX0		3dl9
40	d2v	CP2R1	Vitamin D 25-hydroxylase	Q6VVX0		3czh
41	tpf	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	6ma7
42	myt	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	1w0g, 6ma6
43	mwy	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	6ooa
44	mwv	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	6oo9
45	mws	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	6oob
46	kln	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	2v0m
47	dj1	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	6bdk
48	d81	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	6bd8
49	d0r	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	3tjs
50	8aw	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	4k9x
51	6aw	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	4k9v
52	08y	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	3ua1, 5vcg
53	2qh	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	4ny4
54	08j	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	5te8
55	d7m	CP3A4	Cytochrome P450 3A4	P08684	CYP3A3	6bd5
56	c3s	CP46A	Cholesterol 24-hydroxylase	Q9Y6A2	CYP46	2q9f
57	vor	CP46A	Cholesterol 24-hydroxylase	Q9Y6A2	CYP46	3mdt
58	fvx	CP46A	Cholesterol 24-hydroxylase	Q9Y6A2	CYP46	4enh
59	vfv	CP51A	Lanosterol 14-alpha demethylase	Q16850	CYP51	4uhi
60	kkk	CP51A	Lanosterol 14-alpha demethylase	Q16850	CYP51	3ld6
61	ecn	CP51A	Lanosterol 14-alpha demethylase	Q16850	CYP51	3jus
62	ecl	CP51A	Lanosterol 14-alpha demethylase	Q16850	CYP51	3jus
63	k2b	CP7A1	Cholesterol 7-alpha-monooxygenase	P22680	CYP7	3sn5
64	0gv	CP7A1	Cholesterol 7-alpha-monooxygenase	P22680	CYP7	3v8d
65	mxd	PTGIS	Prostacyclin synthase	Q16647	CYP8 CYP8A1	3b6h