The Ligandable Human Proteome

Index	Gene Name Primary	Protein Name	Uniprot ID	Gene Name Synonym	Ligand Name	Structure	PDB Code	ligand desolvation	Compound Affinity nM
1	ANDR	Androgen receptor	P10275	DHTR NR3C4	t3	Androgen receptor with small molecule	2piw	55.29	no data
2	ANDR	Androgen receptor	P10275	DHTR NR3C4	enm	Crystal structure of human androgen receptor ligand-binding domain in complex with EM-5744	2pnu	99.81	no data
3	ANDR	Androgen receptor	P10275	DHTR NR3C4	4hy	Androgen receptor LBD with small molecule	2piu	63.51	no data
4	ANDR	Androgen receptor	P10275	DHTR NR3C4	056	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING	2ylp	66.36	50000.
5	ANDR	Androgen receptor	P10275	DHTR NR3C4	zk5	Structural basis for the glucocorticoid response in a mutant human androgen receptor (ARccr) derived from an androgen-independent prostate cancer	1gs4	99.81	no data
6	ANDR	Androgen receptor	P10275	DHTR NR3C4	17h	Crystal structure of human androgen receptor ligand binding domain in complex with tetrahydrogestrinone	2amb	100	no data
7	ANDR	Androgen receptor	P10275	DHTR NR3C4	r18	Human Androgen Receptor Ligand Binding in complex with the ligand metribolone (R1881)	1e3g	99.88	0.99
8	ANDR	Androgen receptor	P10275	DHTR NR3C4	r18	Crystal structure of the human androgen receptor ligand binding domain bound with an androgen receptor NH2-terminal peptide, AR20-30, and R1881	1xow	100	0.52
9	ANDR	Androgen receptor	P10275	DHTR NR3C4	r18	Crystal structure of the human androgen receptor ligand binding domain bound with R1881	1xq3	99.77	no data
10	ANDR	Androgen receptor	P10275	DHTR NR3C4	r18	Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753 peptide and R1881	2ao6	100	0.52
11	ANDR	Androgen receptor	P10275	DHTR NR3C4	k10	Androgen receptor LBD with small molecule	2pip	65.52	no data
12	ANDR	Androgen receptor	P10275	DHTR NR3C4	rb1	androgen receptor LBD with small molecule	2piq	64.57	no data
13	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING	3zqt	100	no data
14	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	Human androgen receptor in complex with AF2 small molecule inhibitor	2yhd	100	no data
15	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzoimidazole derivatives.	4hlw	100	no data
16	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	Crystal structure of human androgen receptor ligand binding domain in complex with testosterone	2am9	100	3.9
17	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING	2ylp	100	no data
18	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING	2ylq	100	no data
19	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING	2ylo	100	no data
20	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and a TIF2 box3 Coactivator Peptide 740-753	2q7l	100	no data
21	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	The Wild Type Androgen Receptor Ligand Binding Domain Bound with Testosterone and an AR 20-30 Peptide	2q7i	100	no data
22	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	The Androgen Receptor Prostate Cancer Mutant H874Y Ligand Binding Domain Bound with Testosterone and an AR 20-30 Peptide	2q7k	100	no data
23	ANDR	Androgen receptor	P10275	DHTR NR3C4	tes	The Wild Type Androgen Receptor Ligand Binding Domain Bound with Testosterone and a TIF2 box 3 Coactivator Peptide 740-753	2q7j	100	no data
24	ANDR	Androgen receptor	P10275	DHTR NR3C4	av6	Human androgen receptor in complex with AF2 small molecule inhibitor	2yhd	66.42	23000.
25	ANDR	Androgen receptor	P10275	DHTR NR3C4	b5r	Crystal structure of the androgen receptor ligand binding domain in complex with SARM C-31	3b5r	99.27	1.7
26	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal Structure of Homodimeric Androgen Receptor Ligand-Binding Domain bound to DHT and LxxLL peptide	5jjm	99.88	no data
27	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLF motif	1t7r	99.77	no data
28	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with a LxxLL motif	1t7f	100	no data
29	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif	1t79	100	no data
30	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of DHT-bound androgen receptor in complex with the third motif of steroid receptor coactivator 3	3l3z	100	no data
31	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of DHT-bound androgen receptor in complex with the first motif of steroid receptor coactivator 3	3l3x	100	no data
32	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	AR LBD with small molecule	2qpy	99.79	no data
33	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with 5-alpha dihydrotestosterone	1t7t	100	no data
34	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with a FxxYF motif	1t7m	100	no data
35	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with a WxxLF motif	1t74	99.88	no data
36	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with a WxxVW motif	1t76	100	no data
37	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with a FxxFF motif	1t73	100	no data
38	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor LBD with small molecule	2pio	99.67	no data
39	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	AR LBD with small molecule	2pix	99.89	no data
40	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor LBD with small molecule	2pir	99.58	no data
41	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor LBD with small molecule	2pip	99.58	no data
42	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	androgen receptor LBD with small molecule	2piq	99.91	no data
43	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor with small molecule	2piv	99.47	no data
44	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor with small molecule	2piw	100	no data
45	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor LBD with small molecule	2pit	99.67	no data
46	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor LBD with small molecule	2piu	100	no data
47	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal Structure of the Androgen Receptor Ligand Binding Domain with DHT and a peptide derived from its physiological coactivator GRIP1 NR box3	1t63	99.77	no data
48	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation	1t65	99.88	no data
49	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of AR-LBD bound with co-regulator peptide	4oed	100	no data
50	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of AR-LBD bound with co-regulator peptide	4oez	100	no data
51	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of AR-LBD bound with co-regulator peptide	4oey	100	no data
52	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN T877A MUTANT COMPLEX WITH DIHYDROTESTOSTERONE	1i38	100	no data
53	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN COMPLEX WITH DIHYDROTESTOSTERONE	1i37	100	0.27
54	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of human androgen receptor ligand binding domain in complex with dihydrotestosterone	2ama	99.88	10.
55	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal Structure of the Androgen Receptor Ligand Binding Domain (LBD) with DHT and a peptide derived from its physiological coactivator ARA70	1t5z	99.77	no data
56	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil	4k7a	100	no data
57	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Complex Androgen Receptor LBD and RAC3 peptide	1xj7	99.49	no data
58	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Androgen receptor LBD with small molecule	2pkl	100	no data
59	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of AR LBD with SHP peptide NR Box 2	2z4j	100	no data
60	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of AR-LBD bound with co-regulator peptide	4ofu	100	no data
61	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of AR-LBD bound with co-regulator peptide	4ofr	100	no data
62	ANDR	Androgen receptor	P10275	DHTR NR3C4	dht	Crystal structure of AR-LBD	4oea	100	no data
63	ANDR	Androgen receptor	P10275	DHTR NR3C4	jad	Crystal structure of Androgen Receptor in complex with the ligand	4ql8	99.81	0.7
64	ERR1	Steroid hormone receptor ERR1	P11474	ERR1 ESRL1 NR3B1	047	Crystal Structure of Human Estrogen-Related Receptor alpha in Complex with a Synthetic Inverse Agonist reveals its Novel Molecular Mechanism	2pjl	95.43	190.
65	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	txf	Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domaind with tamoxifen analog GSK5182	2ewp	95.81	79.
66	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	oht	crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen	1s9q	92.23	no data
67	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	oht	Estrogen Related Receptor Gamma in complex with 4-hydroxy-tamoxifen	2p7z	92.4	262.
68	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	oht	Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a SMRT peptide	2gpv	96.17	no data
69	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	oht	Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen	2gpu	96.3	no data
70	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	des	crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with diethylstilbestrol	1s9p	99.34	no data
71	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	9s6	Crystal structure of Estrogen-related Receptor-3 (ERR-gamma) ligand binding domain with DN201000	6a6k	92.19	no data
72	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	90c	Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434	5yso	92.67	no data
73	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	1ba	Estrogen Related Receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic ligand GSK4716	2gpp	98.82	2000.
74	ERR3	Estrogen-related receptor gamma	P62508	ERR3 ERRG2 KIAA0832 NR3B3	chd	crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen	1s9q	47.05	no data
75	ESR1	Estrogen receptor	P03372	ESR NR3A1	ral	Crystal Structure of Antagonizing Mutant 536S of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to Raloxifene	2qxs	95.84	no data
76	ESR1	Estrogen receptor	P03372	ESR NR3A1	ral	HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH RALOXIFENE	1err	90.38	7.7
77	ESR1	Estrogen receptor	P03372	ESR NR3A1	q97	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Ethoxytriphenylethylene and GRIP Peptide	5t1z	99.82	no data
78	ESR1	Estrogen receptor	P03372	ESR NR3A1	pti	The Structure of Estrogen Receptor in Complex with a Selective and Potent Tetrahydroisochiolin Ligand.	1uom	89.4	19.
79	ESR1	Estrogen receptor	P03372	ESR NR3A1	oht	ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A PHAGE-DISPLAY DERIVED PEPTIDE ANTAGONIST	2bj4	87.3	no data
80	ESR1	Estrogen receptor	P03372	ESR NR3A1	oht	Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S in Complex with 4-hydroxytamoxifen	5w9c	97.17	no data
81	ESR1	Estrogen receptor	P03372	ESR NR3A1	oht	HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 4-HYDROXYTAMOXIFEN	3ert	84.76	0.249
82	ESR1	Estrogen receptor	P03372	ESR NR3A1	ogj	Crystal structure of GDC-0927 bound to estrogen receptor alpha	6pfm	83.99	no data
83	ESR1	Estrogen receptor	P03372	ESR NR3A1	ody	Crystal structure of 8-hydroxychromene compound 30 bound to estrogen receptor alpha	6pet	88.56	no data
84	ESR1	Estrogen receptor	P03372	ESR NR3A1	nd1	Mutant estrogen receptor alpha (ERa) Y537S covalently bound to H3B-6545.	6owc	93.91	no data
85	ESR1	Estrogen receptor	P03372	ESR NR3A1	lvh	ERa_L536S (L536S/C381S/C471S,C530S) in complex with a tricyclic indole (compound 6)	6suo	90.08	no data
86	ESR1	Estrogen receptor	P03372	ESR NR3A1	lrq	ERa_L536S (L536S/C381S/C471S,C530S) in complex with a bridged tetracyclic indole (compound 8)	6sq0	93.54	no data
87	ESR1	Estrogen receptor	P03372	ESR NR3A1	llc	Estrogen receptor alpha ligand-binding domain in complex with a SERM	2r6y	89.45	0.32
88	ESR1	Estrogen receptor	P03372	ESR NR3A1	llb	Estrogen receptor alpha ligand-binding domain complexed to a SERM	2r6w	88.73	0.44
89	ESR1	Estrogen receptor	P03372	ESR NR3A1	l4g	A SERM Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats	2ayr	97.8	0.51
90	ESR1	Estrogen receptor	P03372	ESR NR3A1	ke9	A Novel Oral Selective Estrogen Receptor Down-regulator, AZD9496, drives Tumour Growth Inhibition in Estrogen Receptor positive and ESR1 Mutant Models	5acc	94.71	no data
91	ESR1	Estrogen receptor	P03372	ESR NR3A1	iok	Human estrogen receptor alpha ligand-binding domain in complex with compound 1D	2iok	98.16	1.
92	ESR1	Estrogen receptor	P03372	ESR NR3A1	iog	Human estrogen receptor alpha ligand-binding domain in complex with compound 11F	2iog	98.86	8.
93	ESR1	Estrogen receptor	P03372	ESR NR3A1	h8w	Tricyclic indazoles a novel class of selective estrogen receptor degrader antagonists	6iar	97.86	no data
94	ESR1	Estrogen receptor	P03372	ESR NR3A1	gw5	Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist	5aav	96.12	no data
95	ESR1	Estrogen receptor	P03372	ESR NR3A1	gw5	Human Estrogen Receptor alpha Ligand-Binding Domain In Complex With GW5638	1r5k	96.74	no data
96	ESR1	Estrogen receptor	P03372	ESR NR3A1	g9j	Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa	6dfn	99.25	no data
97	ESR1	Estrogen receptor	P03372	ESR NR3A1	g9j	Crystal structure of 8-hydroxychromene compound 30 bound to estrogen receptor alpha	6pet	98.31	no data
98	ESR1	Estrogen receptor	P03372	ESR NR3A1	g91	Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa	6dfn	82.23	no data
99	ESR1	Estrogen receptor	P03372	ESR NR3A1	g8y	Crystal structure of estrogen receptor alpha in complex with receptor degrader 16ab	6df6	92.94	no data
100	ESR1	Estrogen receptor	P03372	ESR NR3A1	fys	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with 3OHTPE and GRIP Peptide	6d0f	95.86	no data
101	ESR1	Estrogen receptor	P03372	ESR NR3A1	fnj	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide	6czn	99.39	no data
102	ESR1	Estrogen receptor	P03372	ESR NR3A1	f3d	Estrogen Receptor Alpha Y537S covalently bound to antagonist H3B-5942.	6chw	92.96	no data
103	ESR1	Estrogen receptor	P03372	ESR NR3A1	f3d	Estrogen Receptor Alpha Y537S bound to antagonist H3B-9224.	6chz	79.13	no data
104	ESR1	Estrogen receptor	P03372	ESR NR3A1	ezt	Crystal structure of the ER alpha ligand binding domain with the agonist ortho-trifluoromethylphenylvinyl estradiol	2p15	98.86	0.05
105	ESR1	Estrogen receptor	P03372	ESR NR3A1	etc	Human Estrogen Receptor alpha Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol and a Glucocorticoid Receptor Interacting Protein 1 NR box II Peptide	1l2i	100	no data
106	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with SRC2 Stapled Peptide 41A and Estradiol	6pit	98.65	no data
107	ESR1	Estrogen receptor	P03372	ESR NR3A1	e4d	Human Estrogen Receptor Alpha Ligand-binding Domain in Complex with the Antagonist Ligand 4-D	1sj0	93.01	0.8
108	ESR1	Estrogen receptor	P03372	ESR NR3A1	drq	Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide	2g5o	98.67	no data
109	ESR1	Estrogen receptor	P03372	ESR NR3A1	des	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Diethylstilbestrol	4zn7	100	no data
110	ESR1	Estrogen receptor	P03372	ESR NR3A1	des	HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DIETHYLSTILBESTROL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE	3erd	100	0.126
111	ESR1	Estrogen receptor	P03372	ESR NR3A1	cm4	Human estrogen receptor alpha ligand-binding domain in complex with compound 4	1yim	97.74	no data
112	ESR1	Estrogen receptor	P03372	ESR NR3A1	cm3	Human estrogen receptor alpha ligand-binding domain in complex with compound 3F	1yin	90.46	no data
113	ESR1	Estrogen receptor	P03372	ESR NR3A1	c6v	ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH LSZ102	6b0f	97.98	no data
114	ESR1	Estrogen receptor	P03372	ESR NR3A1	c3d	Crystal Structure of Estrogen Receptor alpha-lasofoxifene complex	2ouz	90.97	no data
115	ESR1	Estrogen receptor	P03372	ESR NR3A1	aiu	HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 16	1xp6	97.5	0.4
116	ESR1	Estrogen receptor	P03372	ESR NR3A1	ait	HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 19	1xpc	96.91	1.7
117	ESR1	Estrogen receptor	P03372	ESR NR3A1	aij	HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 18	1xp9	97.17	1.3
118	ESR1	Estrogen receptor	P03372	ESR NR3A1	aih	HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 15	1xp1	97.19	0.5
119	ESR1	Estrogen receptor	P03372	ESR NR3A1	aej	X-ray structure of ERalpha LBD bound to a tetrahydroisoquinoline SERM ligand at 2.05A resolution	1xqc	92.97	63.
120	ESR1	Estrogen receptor	P03372	ESR NR3A1	9xy	Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen	5w9d	99.51	no data
121	ESR1	Estrogen receptor	P03372	ESR NR3A1	86y	Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1074	5ufx	94.97	no data
122	ESR1	Estrogen receptor	P03372	ESR NR3A1	86v	Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1154	5ufw	94.49	no data
123	ESR1	Estrogen receptor	P03372	ESR NR3A1	85z	Oxyphenylpropenoic acids as Oral Selective Estrogen Receptor Down- Regulators.	5ak2	95.71	3.9
124	ESR1	Estrogen receptor	P03372	ESR NR3A1	85m	Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1156	6c42	95.37	no data
125	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fs	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the estradiol derivative, (8S,9S,13S,14S)-17-((4-isopropylphenyl)amino)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol	5tn3	99.38	no data
126	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fr	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the estradiol derivative, (8S,9S,13S,14S,E)-17-((4-isopropylphenyl)imino)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol	5tn1	98.78	no data
127	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fq	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the estradiol derivative, (8S,9S,13S,14S,17S)-16-(3-methoxybenzyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol	5tmz	98.25	no data
128	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fj	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4'-((1,3-dihydro-2H-inden-2-ylidene)methylene)diphenol	5tmt	98.56	no data
129	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fg	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Cyclofenil-ASC derivative, ethyl (E)-3-(4-(bicyclo[3.3.1]nonan-9-ylidene(4-hydroxyphenyl)methyl)phenyl)acrylate	5tms	100	no data
130	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fd	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Cyclofenil-ASC derivative, ethyl (E)-3-(4-(cyclohexylidene(4-hydroxyphenyl)methyl)phenyl)acrylate	5tmr	97.69	no data
131	ESR1	Estrogen receptor	P03372	ESR NR3A1	7et	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-BSC Analog, 3-fluorophenyl (1R,2R,4S)-5-(4-hydroxyphenyl)-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate and 3-methyl-6-phenyl-3H-imidazo[4,5-b]pyridin-2-amine	5tlp	83.86	no data
132	ESR1	Estrogen receptor	P03372	ESR NR3A1	7ee	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the PEG-linked Dimeric Estrogen, EE2-(eg)6-EE2-amine	5tlu	98.64	no data
133	ESR1	Estrogen receptor	P03372	ESR NR3A1	7ee	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with a Squaric Acid-linked Dimeric Estrogen	5tlo	96.35	no data
134	ESR1	Estrogen receptor	P03372	ESR NR3A1	7eb	Crystal Structure of the ER-alpha Ligand-binding Domain (L372S,L536S) in Complex with the OBHS-BSC, 4-bromophenyl (1R,2R,4S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate	5tnb	91.11	no data
135	ESR1	Estrogen receptor	P03372	ESR NR3A1	7e1	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC compound, (E)-6-(4-((1R,4S,6R)-6-((3-chlorophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenyl)hex-5-enoic acid	5tml	98.36	no data
136	ESR1	Estrogen receptor	P03372	ESR NR3A1	782	ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH (2E)-3-(4-{(1R)-6-hydroxy-1-methyl-2-[4-(propan-2 -yl)phenyl]-1,2,3,4- tetrahydroisoquinolin-1-yl}phenyl)prop-2-enoic acid	5t97	89.17	17.
137	ESR1	Estrogen receptor	P03372	ESR NR3A1	77w	ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH (2E)-3-{4-[(1R)-2-(4-fluorophenyl)-6-hydroxy-1-methy l-1,2,3,4- tetrahydroisoquinolin-1-yl]phenyl}prop-2-enoic acid	5t92	88.76	16.
138	ESR1	Estrogen receptor	P03372	ESR NR3A1	6ww	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Methyl(phenyl)amino-substituted Estrogen, (8R,9S,13S,14S,17S)-13-methyl-17-(methyl(phenyl)amino)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol	5kro	98.77	no data
139	ESR1	Estrogen receptor	P03372	ESR NR3A1	6wv	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the phenylamino-substituted estrogen, (8R,9S,13S,14S,17S)-13-methyl-17-(phenylamino)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol, without a coactivator peptide	5u2b	97.95	no data
140	ESR1	Estrogen receptor	P03372	ESR NR3A1	6wv	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the phenylamino-substituted estrogen, (8R,9S,13S,14S,17S)-13-methyl-17-(phenylamino)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol	5tld	97.11	no data
141	ESR1	Estrogen receptor	P03372	ESR NR3A1	6wq	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4'-((5-bromo-2,3-dihydro-1H-inden-1-ylidene)methylene)diphenol	5krk	99.84	no data
142	ESR1	Estrogen receptor	P03372	ESR NR3A1	6wn	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 16-benzylidene estrone	5krh	97.75	no data
143	ESR1	Estrogen receptor	P03372	ESR NR3A1	6wm	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 16b-benzyl 17b-estradiol	5kri	97.26	no data
144	ESR1	Estrogen receptor	P03372	ESR NR3A1	5kg	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol	5dzh	99.67	no data
145	ESR1	Estrogen receptor	P03372	ESR NR3A1	5kf	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol	5dzi	99.92	no data
146	ESR1	Estrogen receptor	P03372	ESR NR3A1	5ke	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(4-hydroxyphenyl)cyclohexylidene]methanediyl}diphenol	5e0w	99.35	no data
147	ESR1	Estrogen receptor	P03372	ESR NR3A1	5kd	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(4-methoxyphenyl)cyclohexylidene]methanediyl}diphenol	5e0x	98.89	no data
148	ESR1	Estrogen receptor	P03372	ESR NR3A1	5kb	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3R)-3-phenylcyclohexylidene]methanediyl}diphenol	5e14	99.36	no data
149	ESR1	Estrogen receptor	P03372	ESR NR3A1	5ka	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol	5e15	95.6	no data
150	ESR1	Estrogen receptor	P03372	ESR NR3A1	5k7	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative methyl {4-[bis(4-hydroxyphenyl)methylidene]cyclohexyl}acetate	5e19	98.89	no data
151	ESR1	Estrogen receptor	P03372	ESR NR3A1	5k5	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(4aR,8aR)-octahydronaphthalen-2(1H)-ylidenemethanediyl]diphenol	5ehj	98.23	no data
152	ESR1	Estrogen receptor	P03372	ESR NR3A1	5k4	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-ethylcyclohexylidene]methanediyl}diphenol	5dy8	99.75	no data
153	ESR1	Estrogen receptor	P03372	ESR NR3A1	5k2	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-(3,4-dihydronaphthalen-2(1H)-ylidenemethanediyl)diphenol	5dyb	99.66	no data
154	ESR1	Estrogen receptor	P03372	ESR NR3A1	5k1	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(methylsulfanyl)cyclohexylidene]methanediyl}diphenol	5dyd	99.92	no data
155	ESR1	Estrogen receptor	P03372	ESR NR3A1	5k0	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(4-methylcyclohexylidene)methanediyl]diphenol	5dz0	99.75	no data
156	ESR1	Estrogen receptor	P03372	ESR NR3A1	5jy	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(4-ethylcyclohexylidene)methanediyl]diphenol	5dz1	99.55	no data
157	ESR1	Estrogen receptor	P03372	ESR NR3A1	5jx	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(fluoromethyl)cyclohexylidene]methanediyl}diphenol	5dz3	99.91	no data
158	ESR1	Estrogen receptor	P03372	ESR NR3A1	5j1	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(9s)-bicyclo[3.3.1]non-9-ylmethanediyl]diphenol	5dxk	99.83	no data
159	ESR1	Estrogen receptor	P03372	ESR NR3A1	5j0	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 3-[(E)-(1s,5s)-bicyclo[3.3.1]non-9-ylidene(4-hydroxyphenyl)methyl]phenol	5dxm	100	no data
160	ESR1	Estrogen receptor	P03372	ESR NR3A1	5hz	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(1s,5s)-bicyclo[3.3.1]non-9-ylidenemethanediyl]diphenol	5dxq	99.91	no data
161	ESR1	Estrogen receptor	P03372	ESR NR3A1	5hx	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4-[(E)-(1s,5s)-bicyclo[3.3.1]non-9-ylidene(phenyl)methyl]phenol	5dxp	99.14	no data
162	ESR1	Estrogen receptor	P03372	ESR NR3A1	5hw	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3R)-3-methylcyclohexylidene]methanediyl}diphenol	5dxr	99.83	no data
163	ESR1	Estrogen receptor	P03372	ESR NR3A1	5fy	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a para-Hydroxyl-substituted, Sulfoxide-bridged Oxabicyclic Heptene Sulfonate (SOBHS)-2 Analog 4-hydroxyphenyl (1S,2S,4S,5S,6R,7S)-5,6-bis(4-hydroxy-2-methylphenyl)-7-thiabicyclo[2.2.1]heptane-2-sulfonate 7-oxide	5due	99.12	no data
164	ESR1	Estrogen receptor	P03372	ESR NR3A1	5es	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 4-fluorophenylamino-substituted triaryl-ethylene derivative 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}ethene-1,1-diyl)diphenol	5dp0	99.61	no data
165	ESR1	Estrogen receptor	P03372	ESR NR3A1	5dg	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 4-fluorophenylamino-substituted, methyl triaryl-ethylene derivative 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}prop-1-ene-1,1-diyl)diphenol	5dmf	97.71	no data
166	ESR1	Estrogen receptor	P03372	ESR NR3A1	5cc	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a phenylamino-substituted ethyl triaryl-ethylene derivative 4,4'-{2-[3-(phenylamino)phenyl]but-1-ene-1,1-diyl}diphenol	5dk9	99.15	no data
167	ESR1	Estrogen receptor	P03372	ESR NR3A1	5c9	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 3-methylphenylamino-substituted ethyl triaryl-ethylene derivative 4,4'-(2-{3-[(3-methylphenyl)amino]phenyl}but-1-ene-1,1-diyl)diphenol	5dkb	96.24	no data
168	ESR1	Estrogen receptor	P03372	ESR NR3A1	5c6	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 2-naphthylamino-substituted, ethyl, triaryl-ethylene derivative 4,4'-{2-[3-(naphthalen-1-ylamino)phenyl]but-1-ene-1,1-diyl}diphenol	5dks	99.88	no data
169	ESR1	Estrogen receptor	P03372	ESR NR3A1	369	Human Estrogen receptor alpha LBD with GW368	3dt3	94.4	no data
170	ESR1	Estrogen receptor	P03372	ESR NR3A1	29s	Estrogen Receptor Alpha Ligand Binding Domain in Complex with Bazedoxifene	4xi3	93.35	no data
171	ESR1	Estrogen receptor	P03372	ESR NR3A1	27h	Crystal structure of hERa-LBD (Y537S) in complex with ferutinine	4mg7	99.9	440.
172	ESR1	Estrogen receptor	P03372	ESR NR3A1	1gs	Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Constrained WAY-derivative, 5b	4iv4	99.37	no data
173	ESR1	Estrogen receptor	P03372	ESR NR3A1	1gr	Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Dynamic WAY-derivative, 5a	4iv2	99.58	no data
174	ESR1	Estrogen receptor	P03372	ESR NR3A1	17m	Human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 NR box II peptide	2b1z	98.55	79.
175	ESR1	Estrogen receptor	P03372	ESR NR3A1	459	Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-2M and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide	2fai	99.27	570.
176	ESR1	Estrogen receptor	P03372	ESR NR3A1	i0g	Benzopyrans are Selective Estrogen Receptor beta Agonists (SERBAs) with Novel Activity in Models of Benign Prostatic Hyperplasia	2i0j	98.07	2.68
177	ESR1	Estrogen receptor	P03372	ESR NR3A1	wst	Benzopyrans as Selective Estrogen Receptor b Agonists (SERBAs). Part 2: Structure Activity Relationship Studies on the Benzopyran Scaffold.	2pog	99.42	0.29
178	ESR1	Estrogen receptor	P03372	ESR NR3A1	dc8	Estrogen receptor alpha ligand-binding domain complxed to a benzopyran ligand	2q70	98.17	8.3
179	ESR1	Estrogen receptor	P03372	ESR NR3A1	jj3	Estrogen receptor alpha ligand-binding domain in complex with a benzopyran agonist	2qe4	98.18	11.
180	ESR1	Estrogen receptor	P03372	ESR NR3A1	eed	Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to an Ether Estradiol Compound	2qgt	99.89	no data
181	ESR1	Estrogen receptor	P03372	ESR NR3A1	1hp	Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain complexed with Burned Meat Compound 4-OH-PhIP	2qse	98.5	no data
182	ESR1	Estrogen receptor	P03372	ESR NR3A1	qso	Crystal structure of hERa-LBD (Y537S) in complex with biochanin A	5jmm	97.7	no data
183	ESR1	Estrogen receptor	P03372	ESR NR3A1	j2z	Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and 16-alpha-hydroxy-estrone ((8S,9R,13S,14R,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one	3hlv	98.61	no data
184	ESR1	Estrogen receptor	P03372	ESR NR3A1	j3z	Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and estrone ((8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one)	3hm1	99.29	no data
185	ESR1	Estrogen receptor	P03372	ESR NR3A1	gen	Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with Genistein	2qa8	98.89	990.
186	ESR1	Estrogen receptor	P03372	ESR NR3A1	gen	CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED WITH GENISTEIN	1x7r	98.41	9.
187	ESR1	Estrogen receptor	P03372	ESR NR3A1	4oh	Crystal Structure of human Estrogen Receptor alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II peptide and Estetrol (Estra-1,3,5(10)-triene-3,15 alpha,16alpha,17beta-tetrol)	3l03	98.61	no data
188	ESR1	Estrogen receptor	P03372	ESR NR3A1	esl	Crystal structure of human estrogen receptor alpha LBD in complex with GRIP peptide and estriol	3q95	98.24	no data
189	ESR1	Estrogen receptor	P03372	ESR NR3A1	zer	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with Zearalenone	5krc	99.36	no data
190	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide	4pxm	98.3	1.3
191	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Estradiol and GRIP Peptide	6cbz	98.29	no data
192	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody	2ocf	99.63	no data
193	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	HUMAN OESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-OESTRADIOL AND TIF2 NRBOX3 PEPTIDE	1gwr	97.81	no data
194	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-SP2 and Estradiol	5hyr	98.79	no data
195	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED TO ESTRADIOL	1a52	97.97	0.138
196	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions	1pcg	98.26	no data
197	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Crystal structure of hERa-LBD (Y537S) in complex with estradiol	3uud	98.06	no data
198	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-BCP1	5wgq	98.25	no data
199	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Crystal structure of estrogen receptor alpha in complex with a stabilized peptide antagonist	5gs4	98.7	no data
200	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	estrogen receptor alpha in complex with a stabilized peptide antagonist 6	5gtr	99.4	no data
201	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	MUTANT ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL	1qkt	97.09	0.92
202	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P3 and Estradiol	5dx3	98.28	no data
203	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P1 and Estradiol	5dxb	98.89	no data
204	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P4 and Estradiol	5dxe	98.89	no data
205	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Stapled Peptide SRC2-P5	5dxg	98.9	no data
206	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	CRYSTAL STRUCTURE OF A WILD TYPE HER ALPHA LBD AT 2.9 ANGSTROM RESOLUTION	1g50	98.56	530.
207	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Stapled Peptides binding to Estrogen Receptor alpha.	2yja	98.93	no data
208	ESR1	Estrogen receptor	P03372	ESR NR3A1	est	Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-LP1	5wgd	98.53	no data
209	ESR1	Estrogen receptor	P03372	ESR NR3A1	27g	Crystal structure of hERa-LBD (Y537S) in complex with benzylbutylphtalate	4mg6	99	2420.
210	ESR1	Estrogen receptor	P03372	ESR NR3A1	27j	Crystal structure of hERa-LBD (Y537S) in complex with alpha-zearalanol	4mg8	100	330.
211	ESR1	Estrogen receptor	P03372	ESR NR3A1	ese	Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with an A-CD ring estrogen derivative	4pps	99.24	no data
212	ESR1	Estrogen receptor	P03372	ESR NR3A1	36j	Crystal structure of hERa-LBD (Y537S) in complex with alpha-zearalenol	4tuz	99.11	no data
213	ESR1	Estrogen receptor	P03372	ESR NR3A1	xbr	Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist	5aau	99.51	no data
214	ESR1	Estrogen receptor	P03372	ESR NR3A1	5cq	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with an methyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(4-hydroxy-2-methylphenyl)-7a-methyloctahydro-1H-inden-1-ol	5di7	99.17	no data
215	ESR1	Estrogen receptor	P03372	ESR NR3A1	5ck	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a difluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol	5did	99.27	no data
216	ESR1	Estrogen receptor	P03372	ESR NR3A1	5cj	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol	5die	98.84	no data
217	ESR1	Estrogen receptor	P03372	ESR NR3A1	5ce	Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoromethyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol	5dig	98.79	no data
218	ESR1	Estrogen receptor	P03372	ESR NR3A1	5fv	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Sulfoxide-bridged Oxabicyclic Heptene Sulfonate (SOBHS)-2 analog phenyl (1S,2S,4S,7S)-5,6-bis(4-hydroxy-2-methylphenyl)-7-thiabicyclo[2.2.1]hept-5-ene-2-sulfonate 7-oxide	5dug	99.84	no data
219	ESR1	Estrogen receptor	P03372	ESR NR3A1	5ft	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Sulfoxide-bridged Oxabicyclic Heptene Sulfonate (SOBHS)-3 analog phenyl (1S,2S,4S,7S)-5,6-bis(4-hydroxy-3-methylphenyl)-7-thiabicyclo[2.2.1]hept-5-ene-2-sulfonate 7-oxide	5duh	99.86	no data
220	ESR1	Estrogen receptor	P03372	ESR NR3A1	5g4	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Triaryl-substituted Imine Analog, 4-{(E)-(4-hydroxyphenyl)[(2-methylphenyl)imino]methyl}benzene-1,3-diol	5dwg	99.75	no data
221	ESR1	Estrogen receptor	P03372	ESR NR3A1	5g3	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Resorcinyl 2-Chloro-substituted Diaryl-imine analog 4-[(E)-[(2-chlorophenyl)imino](4-hydroxyphenyl)methyl]benzene-1,3-diol	5dwi	100	no data
222	ESR1	Estrogen receptor	P03372	ESR NR3A1	5j2	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Resorcinyl 4-Fluoro-substituted Diaryl-imine analog 4-[(E)-[(4-fluorophenyl)imino](4-hydroxyphenyl)methyl]benzene-1,3-diol	5dwj	99.58	no data
223	ESR1	Estrogen receptor	P03372	ESR NR3A1	5k8	Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative dimethyl {(1S)-3-[bis(4-hydroxyphenyl)methylidene]cyclohexyl}propanedioate	5e1c	99.25	no data
224	ESR1	Estrogen receptor	P03372	ESR NR3A1	gqd	Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 1.	5fqp	97.52	19.
225	ESR1	Estrogen receptor	P03372	ESR NR3A1	qhg	Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 2.	5fqr	94.33	26.
226	ESR1	Estrogen receptor	P03372	ESR NR3A1	j0w	Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 3.	5fqs	97.88	44.
227	ESR1	Estrogen receptor	P03372	ESR NR3A1	7qn	Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 4.	5fqt	98.14	160.
228	ESR1	Estrogen receptor	P03372	ESR NR3A1	vqi	Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 5.	5fqv	98.12	610.
229	ESR1	Estrogen receptor	P03372	ESR NR3A1	6wr	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the A-CD ring estrogen, (1S,7aS)-5-(2-chloro-4-hydroxyphenyl)-7a-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-1-ol	5krl	99.25	no data
230	ESR1	Estrogen receptor	P03372	ESR NR3A1	6wu	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the A-CD ring estrogen, (1S,7aS)-5-(2,5-difluoro-4-hydroxyphenyl)-7a-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-1-ol	5krm	99.28	no data
231	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fp	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS derivative, 4-acetamidophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate	5tmw	96.73	no data
232	ESR1	Estrogen receptor	P03372	ESR NR3A1	7fz	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the ACD-ring estrogen, (S)-5-(4-hydroxy-3,5-dimethylphenyl)-2,3-dihydro-1H-inden-1-ol	5tn4	98.23	no data
233	ESR1	Estrogen receptor	P03372	ESR NR3A1	7g0	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the AC-ring estrogen, (1S,3aS,5S,7aS)-5-(4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol	5tn5	98.39	no data
234	ESR1	Estrogen receptor	P03372	ESR NR3A1	7g1	Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Spiro BC-estradiol, (1S,1'S,3a'S,7a'S)-7a'-methyl-1',2,2',3,3',3a',4',6',7',7a'-decahydro-1,5'-spirobi[indene]-1',5-diol	5tn6	98.92	no data
235	ESR1	Estrogen receptor	P03372	ESR NR3A1	27m	Crystal structure of hERa-LBD (Y537S) in complex with benzophenone-2	4mgc	97.38	480.
236	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	oht	A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta	2fsz	89.26	no data
237	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	mon	Estrogen Receptor beta with Selective Triazine Modulator	1nde	95.04	15.
238	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	kb0	HUMAN ESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH KB095285 AND CIA12 COACTIVATOR PEPTIDE	4zi1	100	no data
239	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	etc	Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	1l2j	98.31	no data
240	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	aoe	RAT OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH PURE ANTIOESTROGEN ICI164,384	1hj1	81.95	no data
241	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	789	Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one	1zaf	99.88	20.
242	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	fbr	Human estrogen receptor beta ligand-binding domain in complex with compound 45	2giu	99.61	1.5
243	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	i0g	Benzopyrans are Selective Estrogen Receptor beta Agonists (SERBAs) with Novel Activity in Models of Benign Prostatic Hyperplasia	2i0g	98.41	0.19
244	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	e3o	STRUCTURE OF 17-EPIESTRIOL-BOUND ESTROGEN RECEPTOR BETA LBD IN COMPLEX WITH LXXLL MOTIF FROM NCOA5	2j7y	99.53	no data
245	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	dc8	Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand	2z4b	98.79	0.44
246	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	jj3	Estrogen receptor beta ligand binding domain in complex with a Benzopyran agonist	2jj3	100	0.28
247	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	3as	Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand	2qtu	99.72	0.53
248	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	gen	CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH GENISTEIN	1x7j	99.59	no data
249	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	gen	HUMAN OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH PARTIAL AGONIST GENISTEIN	1qkm	99.78	no data
250	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	wv7	Fragment-Based Design of novel Estrogen Receptor Ligands	3omo	99.46	no data
251	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	w14	Fragment-Based Design of novel Estrogen Receptor Ligands	3omp	99.77	no data
252	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	w23	Fragment-Based Design of novel Estrogen Receptor Ligands	3omq	98.73	no data
253	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	est	Estrogen Receptor in complex with proline-flanked LXXLL peptides	4j26	99.51	no data
254	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	est	STRUCTURE OF ESTRADIOL-BOUND ESTROGEN RECEPTOR BETA LBD IN COMPLEX WITH LXXLL MOTIF FROM NCOA5	2j7x	99.39	1.7
255	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	est	Crystal structure of estrogen receptor beta ligand binding domain	3ols	99.52	no data
256	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	est	Crystal structure of phosphorylated estrogen receptor beta ligand binding domain	3oll	99.16	no data
257	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	est	Estrogen Receptor in complex with proline-flanked LXXLL peptides	4j24	99.27	no data
258	ESR2	Estrogen receptor beta	Q92731	ESTRB NR3A2	est	Crystal Structure of ER beta bound to Estradiol	5toa	99.75	no data
259	GCR	Glucocorticoid receptor	P04150	GRL	r8c	Structure guided design and discovery of Indazole ethers as highly potent, non-steroidal Glucocorticoid receptor modulators	5g5w	98.78	no data
260	GCR	Glucocorticoid receptor	P04150	GRL	nn7	The discovery of potent selective glucocorticoid receptor modulators, suitable for inhalation	4csj	98.51	4.9
261	GCR	Glucocorticoid receptor	P04150	GRL	mof	Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain	4p6w	99.92	0.7
262	GCR	Glucocorticoid receptor	P04150	GRL	lsj	Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Bound to a Dibenzoxapine Sulfonamide	4lsj	99.91	0.268
263	GCR	Glucocorticoid receptor	P04150	GRL	jzs	Glucocorticoid Receptor with Bound alaninamide 10 with TIF2 peptide	3k22	96.62	12.59
264	GCR	Glucocorticoid receptor	P04150	GRL	gw6	Ligand binding domain of the glucocorticoid receptor complexed with fluticazone furoate	3cld	99.84	no data
265	GCR	Glucocorticoid receptor	P04150	GRL	e7t	Discovery of New Selective Glucocorticoid Receptor Agonist Leads	5g3j	98.69	no data
266	GCR	Glucocorticoid receptor	P04150	GRL	8w8	Glucocorticoid Receptor in complex with AZD5423	5nft	98.67	no data
267	GCR	Glucocorticoid receptor	P04150	GRL	866	Glucocorticoid Receptor LBD bound to GSK866	3e7c	98.93	no data
268	GCR	Glucocorticoid receptor	P04150	GRL	486	Structure of the dominant negative mutant Glucocorticoid Receptor alpha (L733K/N734P) complexed with RU-486	5uc3	92.36	no data
269	GCR	Glucocorticoid receptor	P04150	GRL	486	Crystal structure of the antagonist form of human glucocorticoid receptor	3h52	98.52	no data
270	GCR	Glucocorticoid receptor	P04150	GRL	486	Crystal Structure of the Antagonist Form of Glucocorticoid Receptor	1nhz	91.2	840.
271	GCR	Glucocorticoid receptor	P04150	GRL	29m	Crystal Structure of the Glucocorticoid Receptor Bound to a Non-steroidal Antagonist Reveals Repositioning and Partial Disordering of Activation Function Helix 12	4mdd	94.2	no data
272	GCR	Glucocorticoid receptor	P04150	GRL	dex	GR in complex with dexamethasone	4udc	99.59	no data
273	GCR	Glucocorticoid receptor	P04150	GRL	dex	CRYSTAL STRUCTURE OF THE AGONIST FORM OF GLUCOCORTICOID RECEPTOR	1p93	99	19.
274	GCR	Glucocorticoid receptor	P04150	GRL	dex	Crystal structure of a dimer complex of the human glucocorticoid receptor ligand-binding domain bound to dexamethasone and a TIF2 coactivator motif	1m2z	98.83	no data
275	GCR	Glucocorticoid receptor	P04150	GRL	hcy	Crystal Structure of cortisol-bound glucocorticoid receptor ligand binding domain	4p6x	99.04	91.
276	GCR	Glucocorticoid receptor	P04150	GRL	b9q	Glucocorticoid Receptor in complex with compound 4	6el6	98.81	no data
277	GCR	Glucocorticoid receptor	P04150	GRL	b9t	Glucocorticoid Receptor in complex with compound 31	6el7	99.5	no data
278	GCR	Glucocorticoid receptor	P04150	GRL	b9w	Glucocorticoid Receptor in complex with AZD9567	6el9	97.53	no data
279	MCR	Mineralocorticoid receptor	P08235	MCR MLR	eyn	Mineralocorticoid receptor in complex with (s)-13	6ggg	99.77	no data
280	MCR	Mineralocorticoid receptor	P08235	MCR MLR	ey8	Mineralocorticoid receptor in complex with (s)-13	6gg8	99.91	no data
281	MCR	Mineralocorticoid receptor	P08235	MCR MLR	ewn	Mineralocorticoid receptor in complex with (s)-13	6gev	100	no data
282	MCR	Mineralocorticoid receptor	P08235	MCR MLR	str	Mineralocorticoid Receptor S810L Mutant with Bound Progesterone	2aa6	100	0.39
283	MCR	Mineralocorticoid receptor	P08235	MCR MLR	str	Mineralocorticoid Receptor with Bound Progesterone	2aa5	100	no data
284	MCR	Mineralocorticoid receptor	P08235	MCR MLR	str	Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to progesterone and harboring the S810L mutation responsible for a severe form of hypertension	1ya3	100	no data
285	MCR	Mineralocorticoid receptor	P08235	MCR MLR	1ca	Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone	2abi	100	no data
286	MCR	Mineralocorticoid receptor	P08235	MCR MLR	1ca	Mineralocorticoid Receptor with Bound Deoxycorticosterone	2aa7	99.9	no data
287	MCR	Mineralocorticoid receptor	P08235	MCR MLR	1ca	Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone and harboring the S810L mutation responsible for a severe form of hypertension	1y9r	99.8	no data
288	MCR	Mineralocorticoid receptor	P08235	MCR MLR	as4	Mineralocorticoid Receptor with Bound Aldosterone	2aa2	99.9	no data
289	MCR	Mineralocorticoid receptor	P08235	MCR MLR	snl	Mineralocorticoid receptor ligand-binding domain with spironolactone	3vhu	100	49.
290	MCR	Mineralocorticoid receptor	P08235	MCR MLR	snl	Mineralocorticoid Receptor Double Mutant with Bound Spironolactone	2ab2	100	no data
291	MCR	Mineralocorticoid receptor	P08235	MCR MLR	snl	Crystal structure of the S810L mutant mineralocorticoid receptor associated with SC9420	2oax	100	2.232
292	MCR	Mineralocorticoid receptor	P08235	MCR MLR	pdn	Mineralocorticoid Receptor Double Mutant with Bound Cortisone	2aax	100	no data
293	MCR	Mineralocorticoid receptor	P08235	MCR MLR	dex	MR in complex with dexamethasone	4uda	100	26.
294	MCR	Mineralocorticoid receptor	P08235	MCR MLR	ld1	Mineralocorticoid receptor ligand-binding domain with non-steroidal antagonist	3vhv	100	510.
295	MCR	Mineralocorticoid receptor	P08235	MCR MLR	ld2	Mineralocorticoid receptor ligand-binding domain with non-steroidal antagonist	3vhv	58.05	no data
296	MCR	Mineralocorticoid receptor	P08235	MCR MLR	hfn	Mineralocorticoid receptor ligand-binding domain with compuond 37a	4pf3	100	51.
297	MCR	Mineralocorticoid receptor	P08235	MCR MLR	60r	Identification of Spirooxindole and Dibenzoxazepine Motifs as Potent Mineralocorticoid Receptor Antagonists	5hcv	99.59	2.
298	MCR	Mineralocorticoid receptor	P08235	MCR MLR	6q0	MCR IN COMPLEX WITH ligand	5l7e	99.44	250.
299	MCR	Mineralocorticoid receptor	P08235	MCR MLR	6qe	MCR IN COMPLEX WITH ligand	5l7g	99.63	16.
300	MCR	Mineralocorticoid receptor	P08235	MCR MLR	c0r	Structural and Biochemical Mechanisms for the Specificity of Hormone Binding and Coactivator Assembly by Mineralocorticoid Receptor	2a3i	100	no data
301	MCR	Mineralocorticoid receptor	P08235	MCR MLR	ecv	The structure of MR in complex with AZD9977.	5mwp	99.81	no data
302	NR1H2	Oxysterols receptor LXR-beta	P55055	LXRB NER UNR	g58	X-ray crystal structure of a Potent Liver X Receptor Modulator	3l0e	99.76	10.
303	NR1H2	Oxysterols receptor LXR-beta	P55055	LXRB NER UNR	co1	X-Ray Crystal Structure of LXR Ligand Binding Domain with 24(S),25-epoxycholesterol	1p8d	98.87	no data
304	NR1H2	Oxysterols receptor LXR-beta	P55055	LXRB NER UNR	965	HUMAN LXR BETA HORMONE RECEPTOR / GW3965 COMPLEX	1pq6	98.88	7.94
305	NR1H2	Oxysterols receptor LXR-beta	P55055	LXRB NER UNR	668	Identification of LXRbeta selective agonists for the treatment of Alzheimer's Disease	5hjp	99.43	no data
306	NR1H3	Oxysterols receptor LXR-alpha	Q13133	LXRA	o90	X-ray structure of benzisoxazole synthetic agonist bound to the LXR-alpha	3ips	94.02	64.
307	NR1H3	Oxysterols receptor LXR-alpha	Q13133	LXRA	o40	X-ray structure of benzisoxazole urea synthetic agonist bound to the LXR-alpha	3ipu	94.78	48.
308	NR1H3	Oxysterols receptor LXR-alpha	Q13133	LXRA	965	X-ray structure of GW3965 synthetic agonist bound to the LXR-alpha	3ipq	98.2	27.
309	NR1H3	Oxysterols receptor LXR-alpha	Q13133	LXRA	668	Identification of LXRbeta selective agonists for the treatment of Alzheimer's Disease	5hjs	96.43	no data
310	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	xx9	Structural basis for small molecule NDB as a selective antagonist of FXR	4oiv	98.8	8290.
311	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	xd4	A novel moderator XD4 for bile acid receptor	5y44	99.33	no data
312	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	p88	FXR bound to isoquinolinecarboxylic acid	3p88	95.26	no data
313	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	ook	Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3,5-difluorobenzoic acid	3ook	99.02	4.
314	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	oof	Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid	3oof	98.04	50.
315	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	omm	Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3-fluorobenzoic acid	3omm	98.64	37.
316	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	omk	Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexyl-N-(2-methylphenyl)ethanamide	3omk	98.05	no data
317	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	olf	Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)-3-methylbenzoic acid	3olf	98.67	20.
318	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	oki	Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide	3oki	97.98	70.
319	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	okh	Crystal structure of human FXR in complex with 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid	3okh	70.09	5720.
320	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	o62	FXR with SRC1 and GSK8062	3dcu	95.95	no data
321	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	niw	A ligand M binding to FXR	5yxl	98.65	no data
322	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	muf	Structure of human FXR in complex with MFA-1 and co-activator peptide	3bej	97.09	no data
323	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	jn3	Crystal Structure of Farnesoid X receptor (FXR) with bound NCoA-2 peptide and CDCA	6hl1	94.4	no data
324	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	fex	A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR	1osh	97.21	no data
325	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	d5h	Crystal structure of human FXR in complex with a functional drug ligand	5y1j	97.57	no data
326	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	chc	Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR	1ot7	95.52	no data
327	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	chc	STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR	1osv	95.17	no data
328	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9r3	Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC180 and 9cRA and SRC1	6a5z	91.51	no data
329	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9r3	FXR-LBD with HNC180 and SRC1	6a5x	99.7	no data
330	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9r0	Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC143 and 9cRA and SRC1	6a5y	95.38	no data
331	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9r0	FXR-LBD with HNC143 and SRC1	6a5w	94.45	no data
332	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9o1	Ligand binding to FARNESOID-X-RECEPTOR	5q1i	98.61	570.
333	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9np	Ligand binding to FARNESOID-X-RECEPTOR	5q1h	98.75	7950.
334	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9nm	Ligand binding to FARNESOID-X-RECEPTOR	5q1g	98.21	263000.
335	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9nj	Ligand binding to FARNESOID-X-RECEPTOR	5q1f	98.75	72.5
336	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9ng	Ligand binding to FARNESOID-X-RECEPTOR	5q1e	98.42	120.
337	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9nd	Ligand binding to FARNESOID-X-RECEPTOR	5q1d	98.1	760.
338	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9na	Ligand binding to FARNESOID-X-RECEPTOR	5q1c	98.1	8.4
339	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9n7	Ligand binding to FARNESOID-X-RECEPTOR	5q1b	98.8	48.7
340	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9n4	Ligand binding to FARNESOID-X-RECEPTOR	5q1a	98.83	9.6
341	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9n1	Ligand binding to FARNESOID-X-RECEPTOR	5q19	98.65	48.
342	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9my	Ligand binding to FARNESOID-X-RECEPTOR	5q18	97.88	67.5
343	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9mv	Ligand binding to FARNESOID-X-RECEPTOR	5q17	97.92	5640.
344	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9ms	Ligand binding to FARNESOID-X-RECEPTOR	5q16	98.48	13.5
345	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9mp	Ligand binding to FARNESOID-X-RECEPTOR	5q15	98.46	8.9
346	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9mm	Ligand binding to FARNESOID-X-RECEPTOR	5q14	98.47	21.
347	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9md	Ligand binding to FARNESOID-X-RECEPTOR	5q13	98.47	91.
348	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9ma	Ligand binding to FARNESOID-X-RECEPTOR	5q12	98.52	4640.
349	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9m7	Ligand binding to FARNESOID-X-RECEPTOR	5q11	99.16	7190.
350	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9m4	Ligand binding to FARNESOID-X-RECEPTOR	5q10	98.37	6280.
351	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9ly	Ligand binding to FARNESOID-X-RECEPTOR	5q0y	98.23	1870.
352	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9lv	Ligand binding to FARNESOID-X-RECEPTOR	5q0w	98.68	58.
353	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9ls	Ligand binding to FARNESOID-X-RECEPTOR	5q0v	98.24	20.5
354	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9lp	Ligand binding to FARNESOID-X-RECEPTOR	5q0u	98.68	175.
355	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9lj	Ligand binding to FARNESOID-X-RECEPTOR	5q0s	98.43	62.
356	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9lg	Ligand binding to FARNESOID-X-RECEPTOR	5q0r	98.71	27000.
357	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9ld	Ligand binding to FARNESOID-X-RECEPTOR	5q0q	99.45	785.
358	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9la	Ligand binding to FARNESOID-X-RECEPTOR	5q0p	98.61	39.
359	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9l7	Ligand binding to FARNESOID-X-RECEPTOR	5q0o	98.59	24.4
360	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9l4	Ligand binding to FARNESOID-X-RECEPTOR	5q0n	97.78	8.7
361	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9l1	Ligand binding to FARNESOID-X-RECEPTOR	5q0m	89.82	7.9
362	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9ky	Ligand binding to FARNESOID-X-RECEPTOR	5q0l	98.51	4360.
363	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9kv	Ligand binding to FARNESOID-X-RECEPTOR	5q0j	98.5	239.
364	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	93u	FXR ligand binding domain	5yxj	99.39	no data
365	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	93r	A ligand F binding to FXR	5yxd	95.53	no data
366	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	89p	FXR bound to a quinolinecarboxylic acid	3p89	97.8	no data
367	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	82x	FXR with SRC1 and GSK826	3hc5	96.66	no data
368	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	643	Identification of an N-oxide pyridine GW4064 analogue as a potent FXR agonist	3fxv	93.03	94.
369	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	643	Ligand binding to FARNESOID-X-RECEPTOR	5q0x	92.6	45.
370	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	635	Complex Structure of FXR Ligand-binding domain with a tetrahydroazepinoindole compound	3l1b	81.7	no data
371	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	59g	FXR with SRC1 and GSK359	3rut	97.66	no data
372	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	37g	FXR with SRC1 and GSK237	3ruu	97.5	no data
373	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	31d	FXR with DM175 and NCoA-2 peptide	4qe8	96.06	no data
374	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	064	FXR with SRC1 and GW4064	3dct	96.86	112.
375	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	jn3	FXR with CDCA and NCoA-2 peptide	4qe6	94.76	no data
376	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	t73	Novel natural FXR modulator with a unique binding mode	5iaw	99.88	no data
377	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	fez	A unique binding model of FXR LBD with feroline	5ick	98.8	no data
378	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	9lm	Ligand binding to FARNESOID-X-RECEPTOR	5q0t	96.61	29000.
379	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	33y	Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)	3fli	99	no data
380	NR1H4	Bile acid receptor	Q96RI1	BAR FXR HRR1 RIP14	33y	A structure of FXR/RXR	5z12	99.16	no data
381	NR1I2	Nuclear receptor subfamily 1 group I member 2	O75469	PXR	xgh	STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND TETHERED WITH SRC co-activator peptide and Compound 25a AKA BICYCLIC HEXAFLUOROISOPROPYL 2 ALCOHOL SULFONAMIDES	6bns	86.97	no data
382	NR1I2	Nuclear receptor subfamily 1 group I member 2	O75469	PXR	kub	CRYSTAL STRUCTURE OF PXR IN COMPLEX WITH XPC-7455	6s41	92.32	no data
383	NR1I2	Nuclear receptor subfamily 1 group I member 2	O75469	PXR	hyf	Crystal Structure of the Human Pregane X Receptor Ligand Binding Domain in Complex with Hyperforin, a Constituent of St. John's Wort	1m13	92.19	27.
384	NR1I2	Nuclear receptor subfamily 1 group I member 2	O75469	PXR	2q4	Crystal Structure Of the Human PXR-LBD In Complex With N-{(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl}-3-hydroxy-3-methylbutanamide	4ny9	93.22	no data
385	NR1I2	Nuclear receptor subfamily 1 group I member 2	O75469	PXR	3wf	Crystal structure of the hPXR-LBD in complex with the synthetic estrogen 17alpha-ethinylestradiol and the pesticide trans-nonachlor	4x1g	98.64	no data
386	NR1I2	Nuclear receptor subfamily 1 group I member 2	O75469	PXR	3wf	Crystal structure of the hPXR-LBD in complex with the synthetic estrogen 17alpha-ethinylestradiol	4x1f	92.86	10.8
387	NR1I2	Nuclear receptor subfamily 1 group I member 2	O75469	PXR	40u	STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN WITH COMPOUND-1	4xhd	93.99	no data
388	NR5A2	Nuclear receptor subfamily 5 group A member 2	O00482	B1F CPF FTF	rjw	Human Liver Receptor Homologue-1 (LRH-1) Bound to RJW100 and a Fragment of TIF-2	5l11	96.57	no data
389	NR5A2	Nuclear receptor subfamily 5 group A member 2	O00482	B1F CPF FTF	rjw	Structure of Human Liver Receptor Homolog 1 in complex with PGC1a and RJW100	5unj	97.13	no data
390	NR5A2	Nuclear receptor subfamily 5 group A member 2	O00482	B1F CPF FTF	n2j	Human LRH-1 bound to the agonist 6N and a fragment of the Tif2 coregulator	6oqy	97.45	no data
391	NR5A2	Nuclear receptor subfamily 5 group A member 2	O00482	B1F CPF FTF	n27	Human LRH-1 bound to the agonist 2N and a fragment of the Tif2 coregulator	6or1	96.94	no data
392	NR5A2	Nuclear receptor subfamily 5 group A member 2	O00482	B1F CPF FTF	n1v	Human Liver Receptor Homolog-1 bound to the agonist 5N and a fragment of the Tif2 coregulator	6oqx	97.77	no data
393	NR5A2	Nuclear receptor subfamily 5 group A member 2	O00482	B1F CPF FTF	71w	Human Liver Receptor Homologue-1 (LRH-1) Bound to a RJW100 stereoisomer and a Fragment of TIF-2	5syz	96.44	no data
394	NR5A2	Nuclear receptor subfamily 5 group A member 2	O00482	B1F CPF FTF	470	Human LRH1 LBD bound to GR470	3plz	97.02	no data
395	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	s44	Human PPAR alpha ligand binding domain in complex with a synthetic agonist TIPP703	2znn	95.88	no data
396	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	rew	Crystal Structure of PPARalpha ligand binding domain with BMS-631707	2rew	94.86	no data
397	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	nks	Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-((4-methylphenoxy)carbonyl)glycine	3kdu	97.8	347.
398	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	mmb	the crystal structure of the human PPARaplpha ligand binding domain in complex with a a-hydroxyimino phenylpropanoic acid	2npa	95.83	no data
399	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	ctm	Design and biological evaluation of novel, balanced dual PPARa/g agonists	3fei	95.03	20.
400	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	735	a crystal structure of PPAR alpha bound with SRC1 peptide and GW735	2p54	97.82	no data
401	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	544	The 2.5 Angstrom resolution crystal structure of the human PPARalpha ligand binding domain bound with GW409544 and a co-activator peptide.	1k7l	97.14	no data
402	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	13m	Human PPAR alpha ligand binding domain in complex with a synthetic agonist APHM13	3vi8	96.51	no data
403	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	az2	CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN FROM HUMAN PPAR-ALPHA IN COMPLEX WITH THE AGONIST AZ 242	1i7g	95.66	1000.
404	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	ro7	Aleglitazar, a new, potent, and balanced PPAR alpha/gamma agonist for the treatment of type II diabetes	3g8i	96.56	38.
405	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	7ha	Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine	3kdt	98.17	260.
406	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	il2	Structural basis for iloprost as a dual PPARalpha/delta agonist	3sp6	94.28	no data
407	PPARA	Peroxisome proliferator-activated receptor alpha	Q07869	NR1C1 PPAR	wy1	Structure of PPARalpha in complex with WY14643	4bcr	92.91	no data
408	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	z00	Novel Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) gamma-delta Agonists with High Potency and In-vivo Efficacy	2xyx	96.54	no data
409	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	k55	Human PPAR delta ligand binding domain in complex with a synthetic agonist TIPP204	2znp	97.06	no data
410	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	gw0	Crystal structure PPAR delta binding GW0742	3tkm	97.88	1.
411	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	gni	3,4,5-Trisubstituted Isoxazoles as Novel PPARdelta Agonists: Part2	2j14	98.1	no data
412	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	d32	Crystal Structure of Peroxisome Proliferator-Activated Receptor Delta (PPARd) in Complex with a Full Agonist	3gz9	98.56	4.
413	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	9lu	Co-crystal structure of an Inhibitor in complex with human PPARdelta LBD	5zxi	97.38	no data
414	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	8rr	Human Peroxisome proliferator-activated receptor (PPAR) delta in complexed with a potent and selective agonist	5y7x	97.63	no data
415	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	89l	Co-crystal structure of Inhibitor compound in complex with human PPARdelta LBD	5xmx	98.08	no data
416	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7v4	Human PPARdelta ligand-binding domain in complexed with specific agonist 3	5u3s	98.68	no data
417	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7v1	Human PPARdelta ligand-binding domain in complexed with specific agonist 2	5u3r	98.61	no data
418	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7uy	Human PPARdelta ligand-binding domain in complexed with specific agonist 4	5u3t	98.53	no data
419	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7uj	Human PPARdelta ligand-binding domain in complexed with specific agonist 1	5u3q	98.46	no data
420	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7ug	Human PPARdelta ligand-binding domain in complexed with specific agonist 16	5u41	98.61	no data
421	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7ua	Human PPARdelta ligand-binding domain in complexed with specific agonist 10	5u3z	98.33	no data
422	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7u7	Human PPARdelta ligand-binding domain in complexed with specific agonist 9	5u3y	98.69	no data
423	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7u4	Human PPARdelta ligand-binding domain in complexed with specific agonist 8	5u3x	98.57	no data
424	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7u1	Human PPARdelta ligand-binding domain in complexed with specific agonist 7	5u3w	97.45	no data
425	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7ty	Human PPARdelta ligand-binding domain in complexed with specific agonist 6	5u3v	98.41	no data
426	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7tv	Human PPARdelta ligand-binding domain in complexed with specific agonist 5	5u3u	98.63	no data
427	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7t1	Human PPARdelta ligand-binding domain in complexed with GW501516	5u46	98.15	no data
428	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7sy	Human PPARdelta ligand-binding domain in complexed with specific agonist 14	5u45	98.09	no data
429	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7sv	Human PPARdelta ligand-binding domain in complexed with specific agonist 13	5u44	96.33	no data
430	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7ss	Human PPARdelta ligand-binding domain in complexed with specific agonist 12	5u43	98.15	no data
431	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	7sm	Human PPARdelta ligand-binding domain in complexed with specific agonist 11	5u42	98.3	no data
432	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	433	MOLECULAR RECOGNITION OF FATTY ACIDS BY PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS	1gwx	94.27	no data
433	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	401	Human PPAR delta ligand binding domain in complex with a synthetic agonist TIPP401	2znq	97.4	no data
434	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	331	Crystal structure of PPAR delta complexed with GW2331	1y0s	93.91	no data
435	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	1fa	Ligand binding domain of PPAR delta receptor in complex with a partial agonist	2q5g	89.38	no data
436	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	l41	Crystal Structure of PPAR-delta complex	3d5f	97.52	no data
437	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	dy6	PPARdelta complexed with an anthranilic acid partial agonist	3dy6	96.53	126.
438	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	3oz	PPAR Delta in complex with azppard02	3oz0	95.94	no data
439	PPARD	Peroxisome proliferator-activated receptor delta	Q03181	NR1C2 PPARB	il2	Structural basis for iloprost as a dual PPARalpha/delta agonist	3sp9	97.01	no data
440	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	xcx	Crystal Structure of PPARgamma with an achiral ureidofibrate derivative (RT86)	3r8i	92.32	4500.
441	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	v77	Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selective PPAR-gamma modulator VSP-77	6ms7	89.99	no data
442	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	tls	Crystal Structure of PPARgamma complexed with Telmisartan	3vn2	95.59	no data
443	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	t53	Human PPARgamma ligand binding dmain complexed with SB1453 in a covalent bonded form	5dvc	90.76	no data
444	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	t51	Human PPARgamma ligand binding dmain complexed with SB1451 in a covalent bonded form	5dv8	86.79	no data
445	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	sfi	PPARgamma ligand binding domain in complex with sulindac sulfide	4xuh	79.39	1870.
446	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	s44	Human PPAR gamma ligand binding domain in complex with a synthetic agonist TIPP703	2zno	86.78	no data
447	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	rrg	Crystal Structure of PPARgamma with the ligand JO21	4e4k	94.21	no data
448	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ro0	A novel anti-adipogenic partial agonist of peroxisome proliferator-activated receptor-gamma (PPARG) recruits pparg-coactivator-1 alpha (PGC1A) but potentiates insulin signaling in vitro	2fvj	95.98	no data
449	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	nsi	Crystal Structure of PPAR Gamma with N-sulfonyl-2-indole carboxamide ligands	2hfp	94.87	3.
450	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	m7s	Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO3S	3an3	87.1	no data
451	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	m7r	Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO4R	3an4	88.61	no data
452	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	m0t	Ligand binding domain of PPARgamma complexed with a benzimidazole partial agonist	3s9s	96.31	no data
453	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	l92	X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist	2q8s	88.51	185.
454	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	kk4	Crystal Structure of PPARgamma Ligand Binding Domain in complex with dibenzooxepine derivative compound-9	6ad9	97.03	no data
455	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	j53	Human PPAR gamma ligand binding domain in complex with JKPL53	3vji	87	no data
456	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	j35	Human PPAR GAMMA ligand binding domain in complex with JKPL35	3vjh	86.45	no data
457	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	gw4	PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709	2pob	93.17	no data
458	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	gh1	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602	6dh9	92.44	no data
459	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	gfv	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Hydroxy Pioglitazone (M-IV)	6dha	93.75	no data
460	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	gev	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Darglitazone	6dgl	91.95	no data
461	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	gbv	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with CAY10506	6dgq	86.28	no data
462	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ft7	PPARg LBD in Complex with SR1988	6d3e	91.72	no data
463	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	eks	PPARg LBD bound to SR10171	6c5q	91.27	no data
464	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ek8	Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28	3vsp	91.47	no data
465	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ek1	Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt21	3vso	92.6	no data
466	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	eha	Crystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist	2f4b	92.61	50.
467	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	eey	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907	6c1i	97.01	no data
468	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	edk	PPAR gamma mutant complex	6fzg	97.27	no data
469	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	edk	PPAR mutant complex	6fzf	98.12	no data
470	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	edk	PPAR gamma complex	6fzp	96.9	no data
471	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	edk	PPAR gamma mutant complex	6fzj	98.58	no data
472	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	edk	PPAR gamma LBD complexed with the agonist GW1929	6d8x	97.29	no data
473	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	edk	Crystal structure of PPAR gamma in complex with Mediator of RNA polymerase II transcription subunit 1	6d94	97.57	no data
474	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	dry	Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists	2hwq	88.17	no data
475	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	drj	Crystal structure of the complex between PPARgamma and the agonist LT160 (ureidofibrate derivative)	2i4j	95.37	684.8
476	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	drh	Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). Structure obtained from crystals of the apo-form soaked for 30 days.	2i4p	91.98	1978.
477	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	drh	Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). This structure has been obtained from crystals soaked for 6 hours.	2i4z	95.22	1978.
478	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	drf	Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist	1nyx	92.3	92.
479	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	drd	Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists	2hwr	91.3	no data
480	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ctu	Crystal Structure of PPARgamma Ligand Binding Domain in complex with dibenzooxepine derivative compound-17	6k0t	98.01	no data
481	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ctm	Design and biological evaluation of novel, balanced dual PPARa/g agonists	3fej	90.07	740.
482	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	c01	Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist	1zeo	95.34	210.
483	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Rosiglitazone and Oleic acid	6md4	95.8	no data
484	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ae0	Crystal structure of PPARgamma with compound BR101549	6ilq	89.61	no data
485	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	a9f	Human PPARgamma ligand binding domain complexed with SB1494	6ijs	92.91	no data
486	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	a0l	Crystal structure of PPARgamma with compound BR102375K	6icj	94.8	no data
487	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	7mv	Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selectively PPAR gamma-modulating ligand VSP-51	5two	96.02	8.06
488	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	5bc	Crystal structure of human PPAR-gamma ligand binding domain complex with a potency improved agonist	3noa	95.17	no data
489	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	570	Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the RXRalpha/PPARgamma heterodimer	1rdt	92.89	no data
490	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	570	THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES.	1fm9	93.99	1.
491	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	544	The 2.3 Angstrom resolution crystal structure of the heterodimer of the human PPARgamma and RXRalpha ligand binding domains respectively bound with GW409544 and 9-cis retinoic acid and co-activator peptides.	1k74	96.52	no data
492	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	538	The X-ray Crystal Structure of PPAR-gamma in Complex with an Indole Derivative Modulator, GSK538, and an SRC-1 Peptide	3kmg	94.12	no data
493	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	486	Revealing a steroid receptor ligand as a unique PPARgamma agonist	3qt0	94.23	no data
494	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	3k2	Crystal structure of PPARgammma in complex with SR1663	4r6s	86.95	no data
495	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	3ea	Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist	2ath	92.18	152.
496	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	3e7	Crystal Structure of SR2067 bound to PPARgamma	4r06	95	513.
497	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	2pq	Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with a Potent and Selective Agonist	3gbk	95.19	no data
498	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	24l	Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator	3v9y	89.94	no data
499	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	240	Crystal Structure of PPARgamma LBD bound to full agonist MRL20	2q59	94.51	no data
500	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	14r	Crystal structure of PPARgamma in complex with compound 13	4hee	85.25	no data
501	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	LIGAND-BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA	2prg	90.01	no data
502	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	Structural and Biochemical Basis for Selective Repression of the Orphan Nuclear Receptor LRH-1 by SHP	1zgy	92.81	no data
503	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	Human PPARgamma ligand binding domain complexed with Rosiglitazone	5ycp	92.19	no data
504	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	Crystal Structure of the complex between PPARgamma mutant R357A and rosiglitazone	4o8f	94.79	no data
505	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid	5ji0	94.05	no data
506	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	Human peroxisome proliferator-activated receptor gamma in complex with rosiglitazone	4ema	93.29	no data
507	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a	3cs8	91	no data
508	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	Crystal structure of the human PPARg-LBD/rosiglitazone complex obtained by dry co-crystallization and in situ diffraction	4xld	91.46	no data
509	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	brl	THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES.	1fm6	92.75	no data
510	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	az2	CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST AZ 242	1i7i	89.03	200.
511	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ypa	LIGAND BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA IN COMPLEX WITH A SYNTHETIC AGONIST	1knu	92.93	no data
512	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	208	Structure-based Design of Indole Propionic Acids as Novel PPARag CO-Agonists	2gtk	88.79	251.
513	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	p1b	LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST PIOGLITAZONE	2xkw	90.12	no data
514	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	zaa	X-ray crystal structure of human ppar gamma with 2-(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-2-phenyl-2h-1,2,3-triazol-4-yl)acetic acid	3bc5	93.76	5.
515	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	yrg	Crystal structure of PPAR-gamma LBD complexed with a partial agonist, analogue of clofibric acid	3cdp	93.49	no data
516	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	ro7	Aleglitaar. a new. potent, and balanced dual ppara/g agonist for the treatment of type II diabetes	3g9e	87.94	19.
517	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	imn	PPARgamma ligand binding domain in complex with indomethacin	4xum	98.94	21300.
518	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	imn	Human PPARgamma ligand-binding domain in complex with indomethacin and nitro-233	3adx	99.71	no data
519	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	imn	Human PPARgamma ligand-binding domain in complex with indomethacin	3ads	80.7	9730.
520	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	7va	X-ray Crystal Structure of the PPARgamma Ligand Binding Domain in Complex with Rivoglitazone	5u5l	88.47	14000.
521	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	8a7	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Edaglitazone	5ugm	97.06	no data
522	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	8n6	Structure of PPARgamma ligand binding domain-pioglitazone complex	5y2o	90.9	no data
523	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	8lx	Human PPARgamma ligand binding domain complexed with Lobeglitazone	5ycn	88.14	no data
524	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	8lx	Structure of PPARgamma ligand binding domain - lobeglitazone complex	5y2t	91.46	no data
525	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	bxg	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with SR16832	6aug	92.1	no data
526	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	unt	X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist	3ia6	89.63	3.
527	PPARG	Peroxisome proliferator-activated receptor gamma	P37231	NR1C3	3jx	Crystal Structure of PPARgamma in complex with SR1664	4r2u	89.25	no data
528	PRGR	Progesterone receptor	P06401	NR3C3	mof	Progesterone Receptor Hormone Binding Domain with Bound Mometasone Furoate	1sr7	99.87	0.08
529	PRGR	Progesterone receptor	P06401	NR3C3	gkk	Progesterone Receptor bound to an Alkylpyrrolidine ligand.	3hq5	99.91	16.
530	PRGR	Progesterone receptor	P06401	NR3C3	486	RU486 bound to the progesterone receptor in a destabilized agonistic conformation	2w8y	99.49	0.82
531	PRGR	Progesterone receptor	P06401	NR3C3	ndr	Progesterone Receptor Ligand Binding Domain with bound Norethindrone	1sqn	98.82	0.4
532	PRGR	Progesterone receptor	P06401	NR3C3	str	HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN	1a28	99.89	5.1
533	PRGR	Progesterone receptor	P06401	NR3C3	r18	Human Progesteron Receptor Ligand Binding Domain in complex with the ligand metribolone (R1881)	1e3k	99.56	no data
534	PRGR	Progesterone receptor	P06401	NR3C3	as0	PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids	4a2j	99.69	no data
535	PRGR	Progesterone receptor	P06401	NR3C3	as0	Progesterone Receptor with Bound Asoprisnil and a Peptide from the Co-Repressor NCoR	2ovm	93.7	no data
536	PRGR	Progesterone receptor	P06401	NR3C3	nog	Crystal structure of the human progesterone receptor ligand-binding domain bound to levonorgestrel	3d90	99.02	no data
537	PRGR	Progesterone receptor	P06401	NR3C3	wow	Progesterone receptor bound to sulfonamide pyrrolidine partial agonist	3kba	99.9	16.
538	PRGR	Progesterone receptor	P06401	NR3C3	orb	Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators	3zra	100	no data
539	PRGR	Progesterone receptor	P06401	NR3C3	or8	PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids	4apu	100	no data
540	PRGR	Progesterone receptor	P06401	NR3C3	or8	Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators	3zr7	100	no data
541	PRGR	Progesterone receptor	P06401	NR3C3	or8	Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators	3zrb	100	no data
542	PRGR	Progesterone receptor	P06401	NR3C3	2s0	Progesterone receptor with bound ulipristal acetate and a peptide from the co-repressor SMRT	4oar	90.77	0.038
543	RARA	Retinoic acid receptor alpha	P10276	NR1B1	rea	Crystal structure of a mixed agonist-bound RAR-alpha and antagonist-bound RXR-alpha heterodimer ligand binding domains	3a9e	97.82	no data
544	RARA	Retinoic acid receptor alpha	P10276	NR1B1	luf	Revealing a marine natural product as a novel agonist for retinoic acid receptors with a unique binding mode and antitumor activity	4dqm	94.45	no data
545	RARA	Retinoic acid receptor alpha	P10276	NR1B1	eqo	Crystal structure of RARalpha ligand binding domain in complex with the inverse agonist BMS493 and a corepressor fragment	3kmz	99.34	no data
546	RARA	Retinoic acid receptor alpha	P10276	NR1B1	eqn	Crystal structure of RARalpha ligand binding domain in complex with an agonist ligand (Am580) and a coactivator fragment	3kmr	99.68	no data
547	RARA	Retinoic acid receptor alpha	P10276	NR1B1	bms	CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR AND RXR LIGAND-BINDING DOMAINS	1dkf	96.21	no data
548	RARB	Retinoic acid receptor beta	P10826	HAP NR1B2	ttb	Structure of the ligand binding domain of the Retinoic Acid Receptor beta	1xap	99.6	2.
549	RARB	Retinoic acid receptor beta	P10826	HAP NR1B2	ttb	Crystal structure of RARb LBD homodimer in complex with TTNPB	4dm6	99.02	no data
550	RARB	Retinoic acid receptor beta	P10826	HAP NR1B2	rea	Crystal structure of RARb LBD in complex with 9cis retinoic acid	4dm8	98.83	no data
551	RARB	Retinoic acid receptor beta	P10826	HAP NR1B2	jyi	Crystal structure of RARbeta LBD in complex with selective partial agonist BMS641 [3-chloro-4-[(E)-2-(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)ethenyl]benzoic acid]	4jyi	99.4	no data
552	RARB	Retinoic acid receptor beta	P10826	HAP NR1B2	1ny	Crystal structure of RARbeta LBD in complex with agonist BMS411 [4-{[(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)carbonyl]amino}benzoic acid]	4jyg	99.16	no data
553	RARB	Retinoic acid receptor beta	P10826	HAP NR1B2	9cr	Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator	1xdk	99.14	no data
554	RARG	Retinoic acid receptor gamma	P13631	NR1B3	rea	LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO ALL-TRANS RETINOIC ACID	2lbd	99.72	no data
555	RARG	Retinoic acid receptor gamma	P13631	NR1B3	e9t	Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne	6fx0	99.08	no data
556	RARG	Retinoic acid receptor gamma	P13631	NR1B3	9cr	RARg mutant-S371E	5m24	100	no data
557	RARG	Retinoic acid receptor gamma	P13631	NR1B3	9cr	LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO 9-CIS RETINOIC ACID	3lbd	99.77	no data
558	RARG	Retinoic acid receptor gamma	P13631	NR1B3	564	ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564	1fcy	99.57	3.
559	RARG	Retinoic acid receptor gamma	P13631	NR1B3	254	ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID SR11254	1fd0	99.35	4.
560	RARG	Retinoic acid receptor gamma	P13631	NR1B3	184	ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394	1fcx	99.19	64.
561	RARG	Retinoic acid receptor gamma	P13631	NR1B3	156	ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE PANAGONIST RETINOID BMS181156	1fcz	99.64	0.6
562	RARG	Retinoic acid receptor gamma	P13631	NR1B3	394	ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.	1exa	99.61	no data
563	RARG	Retinoic acid receptor gamma	P13631	NR1B3	961	ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395.	1exx	99.79	no data
564	RARG	Retinoic acid receptor gamma	P13631	NR1B3	961	LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961	4lbd	99.63	no data
565	RORA	Nuclear receptor ROR-alpha	P35398	NR1F1 RZRA	clr	Crystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol	1n83	89.79	no data
566	RORA	Nuclear receptor ROR-alpha	P35398	NR1F1 RZRA	c3s	Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A	1s0x	96.92	no data
567	RORA	Nuclear receptor ROR-alpha	P35398	NR1F1 RZRA	4d8	Crystal structure of the orphan nuclear receptor RORalpha ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8)	4s15	96.31	no data
568	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	zbd	X-ray co-structure of nuclear receptor ROR-GAMMAT + SRC2 peptide with a benzothiadiazole dioxide inverse agonist	4ymq	93.07	1600.
569	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	xgh	IDENTIFICATION OF BICYCLIC HEXAFLUOROISOPROPYL ALCOHOL SULFONAMIDES AS RORGT/RORC INVERSE AGONISTS	6bn6	94.31	no data
570	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	l8a	Crystal structure of RAR-related orphan receptor C in complex with a phenyl (3-phenylpyrrolidin-3-yl)sulfone inhibitor	6o98	97.93	no data
571	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	l7p	RORgamma Ligand Binding Domain	6nwt	98.4	no data
572	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	l77	RORgamma Ligand Binding Domain	6nws	93.94	no data
573	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	hoj	Structure of RORgt in complex with a novel agonist.	6e3g	93.48	no data
574	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	hc9	Crystal structure of orphan nuclear receptor RORgamma in complex with natural ligand	3l0j	95.98	no data
575	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	hc3	Crystal structure of orphan nuclear receptor RORgamma in complex with natural ligand	3l0l	95.35	no data
576	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	hc2	Crystal structure of orphan nuclear receptor RORgamma in complex with natural ligand	3kyt	95.94	no data
577	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	hbw	Crystal structure of human ROR gamma LBD in complex with a quinoline sulfonamide inverse agonist	6q2w	95.96	no data
578	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	cf7	Structure of RORgt in complex with a novel inverse agonist 3	6b33	94.08	no data
579	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	c3s	Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds	5nti	96.3	no data
580	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	b6l	Crystal Structure Analysis of the ROR gamma(C455E)	6j1l	94.62	no data
581	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	98n	Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds	5ntw	96.53	0.6
582	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	98h	Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds	5ntn	94.53	no data
583	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	92a	X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an inverse agonist and SRC2 peptide	5vb5	97.49	350.
584	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	927	X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an inverse agonist and SRC2 peptide	5vb6	95.81	430.
585	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	921	X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an agonist and SRC2 peptide	5vb7	95.25	190.
586	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	8y5	Ligand complex of RORg LBD	5nib	95.3	no data
587	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	8y2	Ligand complex of RORg LBD	5ni8	95.44	no data
588	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	79u	Discovery of phenoxyindazoles and phenylthioindazoles as RORg inverse agonists	5lwp	96.04	no data
589	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	76e	Ligand complex of RORg LBD	5apk	93.73	no data
590	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	76e	Ligand complex of RORg LBD	5apj	92.59	40.
591	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	4y6	Identification of a Novel Allosteric Binding Site for RORgt Inhibitors	5c4t	99.87	21.8
592	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	4y5	Identification of a Novel Allosteric Binding Site for RORgt Inhibitors	5c4s	99.78	3.8
593	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	4q3	RORgamma in complex with inverse agonist 4j.	4zom	90.08	3.
594	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	4p1	RORgamma in complex with inverse agonist 16	4zjw	90.28	220.
595	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	4cz	Crystal structure of RORgamma complexed with SRC2 and compound 5d	5yp5	96.1	no data
596	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	3qq	Crystal structure of RORc in complex with a partial inverse agonist compound	4wlb	95.63	180.
597	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	39k	Crystal structure of RORc in complex with a tertiary sulfonamide inverse agonist	4qm0	99.18	no data
598	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	nbh	Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with small molecule ligand	4nie	94.9	20.
599	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	3sx	Crystal structure of RORc in complex with a benzyl sulfonamide inverse agonist	4wqp	98.84	no data
600	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	vyi	Ligand complex of RORg LBD	5aph	97.31	60.
601	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	4y7	Identification of a Novel Allosteric Binding Site for RORgt Inhibitors	5c4u	99.78	1.9
602	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	6qp	Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with SBI0654919	5k6e	92.44	no data
603	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	q6y	Synthesis and biological evaluation of new triazolo and imidazolopyridine RORgt inverse agonists	5m96	95.29	no data
604	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	98e	Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds	5ntp	93.85	0.7
605	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	f7m	HUMAN RETENOID-RELATED ORPHAN RECEPTOR-GAMMA LIGAND- BINDING DOMAIN IN COMPLEX WITH INDOLE LIGAND CP9b IN INVERSE AGONIST CONFORMATION	6cn5	95.48	no data
606	RORG	Nuclear receptor ROR-gamma	P51449	NR1F3 RORG RZRG	f7j	RORC2 LBD complexed with compound 34	6cn6	95.82	no data
607	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	rea	Liver X-Receptor alpha Ligand Binding Domain with SB313987	2acl	97.98	no data
608	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	rea	humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186	3fal	90.03	no data
609	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	rea	hRXRalpha & mLXRalpha with an indole Pharmacophore, SB786875	3fc6	91.03	no data
610	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	r4m	CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (R)4-METHYL 9cUAB30 AND COACTIVATOR PEPTIDE GRIP-1	4m8h	99	25.
611	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	i5w	Crystal structure of the Retinoid X Receptor alpha in complex with synthetic honokiol derivative 7 and a fragment of the TIF2 co-activator.	5mk4	98.49	no data
612	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9ra	Crystal Structure of Peroxisome Proliferator-Activated Receptor Gamma (PPARg) and Retinoic Acid Receptor Alpha (RXRa) in Complex with 9-cis Retinoic Acid, Co-activator Peptide, and a Partial Agonist	3h0a	97.12	no data
613	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9ra	Crystal structure of human retinoid X receptor alpha-ligand binding domain complex with Targretin and the coactivator peptide GRIP-1	4k6i	99.6	629.
614	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	CRYSTAL STRUCTURE OF THE HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO 9-CIS RETINOIC ACID	1fby	98.78	no data
615	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC180 and 9cRA and SRC1	6a5z	98.59	no data
616	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC143 and 9cRA and SRC1	6a5y	97.56	no data
617	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	Crystal structure of the mouse CAR/RXR LBD heterodimer bound to TCPOBOP and 9cRA and a TIF2 peptide containg the third LXXLL motifs	1xls	99.01	no data
618	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	The 2.3 Angstrom resolution crystal structure of the heterodimer of the human PPARgamma and RXRalpha ligand binding domains respectively bound with GW409544 and 9-cis retinoic acid and co-activator peptides.	1k74	98.31	no data
619	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid	5ji0	98.14	no data
620	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 9-cis retinoic acid and the coactivator peptide GRIP-1	3oap	97.79	no data
621	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	Crystal Structure of the ligand binding domains of the thyroid receptor:retinoid X receptor complexed with 3,3',5 triiodo-L-thyronine and 9-cis retinoic acid	3uvv	97.48	no data
622	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES.	1fm9	98.37	no data
623	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES.	1fm6	97.89	no data
624	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	7o0	Crystal structure of the Retinoid X Receptor alpha in complex with synthetichonokiol derivative 3 and a fragment of the TIF2 co-activator.	5mj5	99.77	no data
625	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	7be	Crystal structure of the Retinoic Acid Receptor alpha in complex with a synthetic spiroketal agonist and a fragment of the TIF2 co-activator.	5lyq	99.74	no data
626	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	7a4	Crystal Structure of RXR-alpha ligand binding domain complexed with synthetic modulator K8003	5tbp	91.86	6670.
627	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	754	Crystal structure of a mixed agonist-bound RAR-alpha and antagonist-bound RXR-alpha heterodimer ligand binding domains	3a9e	95.19	no data
628	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	5tn	Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-propoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2	2p1v	99.48	no data
629	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	5lo	Retinoic acid receptor alpha in complex with chiral dihydrobenzofuran benzoic acid 9a and a fragment of the coactivator TIF2	5ec9	99.78	no data
630	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	4tn	Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-ethoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2	2p1u	99.28	no data
631	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	4cu	Crystal structure of the Retinoid X Receptor alpha in complex with synthetic honokiol derivative 9 and a fragment of the TIF2 co-activator.	5mkj	98.53	48500.
632	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	3tn	Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-methoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2	2p1t	99.25	no data
633	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	3t2	Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB111 and coactivator peptide GRIP-1	4rme	99.3	no data
634	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	3sw	Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB110 and coactivator peptide GRIP-1	4rmd	99.38	no data
635	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	3sv	Crystal Structure of human retinoid X receptor alpha-ligand binding domain complex with 9cUAB76 and the coactivator peptide GRIP-1	4rmc	99.02	no data
636	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	3rb	Crystal structure of human retinoid X Receptor alpha-ligand binding domain complex with 9cUAB70 and the coactivator peptide GRIP-1	4rfw	98.82	no data
637	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	2vz	Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 6-methyl UAB30 and the coactivator peptide GRIP-1	4pp3	98.17	15.
638	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	2vr	Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 8-methyl UAB30 and the coactivator peptide GRIP-1	4poh	98.88	10.
639	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	2vp	Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 7-methyl UAB30 and the coactivator peptide GRIP-1	4poj	99.22	8.
640	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	2e3	Crystal Structure of the Retinoid X Receptor Ligand Binding Domain Bound to the Synthetic Agonist 3-[4-Hydroxy-3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-phenyl]acrylic Acid	3fug	99.64	no data
641	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	29v	CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (S) 4-Methyl 9cUAB30 COACTIVATOR PEPTIDE GRIP-1	4m8e	99.01	13.
642	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	1o8	Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 9cUAB30 and the coactivator peptide GRIP-1	4k4j	98.67	752.
643	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	j57	Crystal structure of the Retinoid X Receptor alpha in complex with synthetic honokiol derivative 4 and a fragment of the TIF2 co-activator.	5mku	99.55	no data
644	RXRA	Retinoic acid receptor RXR-alpha	P19793	NR2B1	9cr	Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator	1xdk	99.14	no data
645	RXRB	Retinoic acid receptor RXR-beta	P28702	NR2B2	lg2	The structure of the human retinoid-X-receptor beta ligand binding domain in complex with the specific synthetic agonist LG100268	1h9u	98.65	no data
646	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	t3	Crystal Structure of T3-Bound Thyroid Hormone Receptor	3gws	100	0.081
647	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	t3	Thyroxine-Thyroid Hormone Receptor Interactions	1xzx	99.89	0.06
648	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	oef	Human Thyroid hormone receptor beta ligand binding domain in complex with KB131084	2j4a	99.85	0.025
649	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	g24	Crystal Structure of Human Thyroid Hormone Receptor beta LBD in complex with specific agonist GC-24	1q4x	98.41	0.33
650	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	8ho	THRb mutation with a novel agonist	6knw	99.35	no data
651	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	8ho	A novel agonist of THRb	6kkb	99.02	no data
652	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	8ho	THRb mutation with a novel agonist	6kke	98.86	no data
653	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	8ho	THRb mutation with a novel agonist	6knv	99.47	no data
654	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	4hy	Thyroid receptor beta in complex with inhibitor	2pin	98.77	no data
655	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	4hy	TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD	1nq1	99.21	no data
656	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	4hy	TR Variant D355R	3d57	98.66	no data
657	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	4hy	TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD	1nq0	98.27	0.048
658	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	4hy	Two RTH Mutants with Impaired Hormone Binding	1nq2	97.59	no data
659	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	4hy	Crystal Structure of TR-beta bound to the selective thyromimetic TRIAC	3jzc	98.93	2.94
660	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	442	Crystal structure of the thyroid hormone receptor beta ligand binding domain in complex with a beta selective compound	1r6g	99.84	0.62
661	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	pfa	CRYSTAL STRUCTURE OF HUMAN TR BETA LIGAND-BINDING DOMAIN COMPLEXED WITH A POTENT SUBTYPE-SELECTIVE THYROMIMETIC	1n46	100	0.03
662	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	ih5	Thyroid receptor beta1 in complex with a beta-selective ligand	1nax	99.85	370.
663	THB	Thyroid hormone receptor beta	P10828	ERBA2 NR1A2 THR1	b72	Structure of TR-beta bound to selective thyromimetic GC-1	3imy	99.91	0.2
664	VDR	Vitamin D3 receptor	P11473	NR1I1	zyd	Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1alpha,25-Dihydroxyvitamin D3 with Substituents at C-18	3p8x	98.63	no data
665	VDR	Vitamin D3 receptor	P11473	NR1I1	zne	Crystal structure of a novel vitamin D3 analogue, ZK203278 showing dissociated profile	3kpz	98.93	no data
666	VDR	Vitamin D3 receptor	P11473	NR1I1	vhw	Crystal structure of the human vitamin D receptor ligand binding domain complexed with 4-MP	3vhw	99.58	no data
667	VDR	Vitamin D3 receptor	P11473	NR1I1	vdx	Crystal structure of VDR H305Q mutant	3m7r	98.48	no data
668	VDR	Vitamin D3 receptor	P11473	NR1I1	vdx	CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D COMPLEXED TO VITAMIN D	1db1	98.92	0.55
669	VDR	Vitamin D3 receptor	P11473	NR1I1	vdx	Crystal Structure Of The Nuclear Receptor For Vitamin D Ligand Binding Domain Bound to MC1288	1ie9	99.29	0.065
670	VDR	Vitamin D3 receptor	P11473	NR1I1	tfy	Crystal structure of the human vitamin D receptor ligand binding domain complexed with 1alpha,25-Dihydroxy-2alpha-[2-(1H-tetrazole-1-yl)ethyl]vitamin D3	4itf	99.54	no data
671	VDR	Vitamin D3 receptor	P11473	NR1I1	tey	Crystal structure of the human vitamin D receptor ligand binding domain complexed with 1alpha,25-Dihydroxy-2alpha-[2-(2H-tetrazol-2-yl)ethyl]vitamin D3	4ite	99.61	no data
672	VDR	Vitamin D3 receptor	P11473	NR1I1	occ	Crystal structure of VDR LBD in complex with 2 alpha-(3-hydroxy-1-propoxy) calcitriol	2har	99.48	no data
673	VDR	Vitamin D3 receptor	P11473	NR1I1	o1c	Crystal structure of VDR LBD in complex with 2alpha(3-hydroxy-1-propyl) calcitriol	2hb7	99.74	no data
674	VDR	Vitamin D3 receptor	P11473	NR1I1	mvd	Crystal structure of VDR LBD in complex with 2alpha-methyl calcitriol	2hb8	99.12	no data
675	VDR	Vitamin D3 receptor	P11473	NR1I1	mc9	Crystal structure of VDR ligand binding domain complexed to calcipotriol.	1s19	98.78	0.31
676	VDR	Vitamin D3 receptor	P11473	NR1I1	kh1	Crystal Structure Of The Nuclear Receptor For Vitamin D Ligand Binding Domain Bound to KH1060	1ie8	99.2	no data
677	VDR	Vitamin D3 receptor	P11473	NR1I1	fmv	Design, Synthesis, Evaluation and Structure of Vitamin D Analogues with Furan Side Chains	3tkc	99.07	no data
678	VDR	Vitamin D3 receptor	P11473	NR1I1	fmv	Design, Chemical synthesis, Functional characterization and Crystal structure of the sidechain analogue of 1,25-dihydroxyvitamin D3.	3ogt	99.09	no data
679	VDR	Vitamin D3 receptor	P11473	NR1I1	eim	Crystal structure of the human vitamin D receptor ligand binding domain complexed with 15alpha-methoxy-1alpha,25-dihydroxyvitamin D3	3ax8	98.8	no data
680	VDR	Vitamin D3 receptor	P11473	NR1I1	ed9	Crystal Structure Analysis of Vitamin D receptor	3wgp	99.33	no data
681	VDR	Vitamin D3 receptor	P11473	NR1I1	eb1	Crystal structure of the VDR LBD complexed to seocalcitol.	1s0z	99.15	no data
682	VDR	Vitamin D3 receptor	P11473	NR1I1	ds5	Crystal Structure Analysis of Vitamin D receptor	3w0a	99.68	no data
683	VDR	Vitamin D3 receptor	P11473	NR1I1	ds4	Crystal Structure Analysis of Vitamin D receptor	3w0y	99.46	no data
684	VDR	Vitamin D3 receptor	P11473	NR1I1	ds3	Crystal Structure Analysis of Vitamin D receptor	3az2	98.98	no data
685	VDR	Vitamin D3 receptor	P11473	NR1I1	ds2	Crystal Structure Analysis of Vitamin D receptor	3az1	99.29	no data
686	VDR	Vitamin D3 receptor	P11473	NR1I1	cov	Structure-based design of a superagonist ligand for the vitamin D nuclear receptor	3cs4	99.15	no data
687	VDR	Vitamin D3 receptor	P11473	NR1I1	ca9	Crystal structure of the human vitamin D receptor ligand binding domain complexed with Yne-diene type analog of active 14-epi-2alpha-methyl-19-norvitamin D3	3auq	98.93	no data
688	VDR	Vitamin D3 receptor	P11473	NR1I1	ca9	Crystal structure of the human vitamin D receptor ligand binding domain complexed with Yne-diene type analog of active 14-epi-2beta-methyl-19-norvitamin D3	3aur	98.41	no data
689	VDR	Vitamin D3 receptor	P11473	NR1I1	c3o	Crystal structure of VDR LBD in complex with 2alpha-(1-propoxy) calcitriol	2has	99.39	no data
690	VDR	Vitamin D3 receptor	P11473	NR1I1	c33	Crystal structure of VDR LBD complexed to 2alpha-propyl-calcitriol	2ham	99.45	no data
691	VDR	Vitamin D3 receptor	P11473	NR1I1	90o	Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R)-5-[(E)-2-{(1R,3aS,7aR)-1-[(R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl}vinyl]-2-(3-hydroxypropyl)cyclohex-4-ene-1,3-diol	5yt2	99.44	no data
692	VDR	Vitamin D3 receptor	P11473	NR1I1	90l	Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2R,3R)-5-[(E)-2-{(1R,3aS,7aR)-1-[(R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl}vinyl]-2-(3-hydroxypropyl)cyclohex-4-ene-1,3-diol	5ysy	99.58	no data
693	VDR	Vitamin D3 receptor	P11473	NR1I1	8vm	Crystal structure of human vitamin D receptor ligand binding domain in complex with a VDRM	5v39	99.04	no data
694	VDR	Vitamin D3 receptor	P11473	NR1I1	6ds	Crystal Structure Analysis of Vitamin D receptor	3w0c	99.68	no data
695	VDR	Vitamin D3 receptor	P11473	NR1I1	41w	Crystal structure of the human vitamin D receptor ligand binding domain complexed with 7,8-cis-1a,25-Dihydroxy-19-norvitamin D3	3x36	99.13	no data
696	VDR	Vitamin D3 receptor	P11473	NR1I1	41v	Crystal structure of the human vitamin D receptor ligand binding domain complexed with 7,8-cis-14-epi-1a,25-Dihydroxy-19-norvitamin D3	3x31	99.07	no data
697	VDR	Vitamin D3 receptor	P11473	NR1I1	3ev	Crystal structure of the human VDR ligand binding domain bound to the natural metabolite 1alpha,25-dihydroxy-3-epi-vitamin D3	3a78	99.34	no data
698	VDR	Vitamin D3 receptor	P11473	NR1I1	2mv	Crystal structure of the human VDR ligand binding domain bound to the synthetic agonist compound 2alpha-methyl-AMCR277A(C23S)	3a3z	99.32	no data
699	VDR	Vitamin D3 receptor	P11473	NR1I1	2kb	Crystal structure of the human vitamin D receptor ligand binding domain complexed with (1R,2S,3R,5Z,7E,14beta,17alpha)-2-cyanopropoxy-9,10-secocholesta-5,7,10-triene-1,3,25-triol	5gt4	99.34	no data
700	VDR	Vitamin D3 receptor	P11473	NR1I1	23r	Crystal structure of the human VDR ligand binding domain bound to the synthetic agonist compound 2alpha-methyl-AMCR277B(C23R)	3a40	99.25	no data
701	VDR	Vitamin D3 receptor	P11473	NR1I1	0co	Structure-based design of a superagonist ligand for the vitamin D nuclear receptor	3cs6	99.15	no data
702	VDR	Vitamin D3 receptor	P11473	NR1I1	tx5	Crystal structure of the vdr ligand binding domain complexed to TX522	1txi	98.17	no data
703	VDR	Vitamin D3 receptor	P11473	NR1I1	tej	Crystal structure of the human vitamin D receptor (H305F/H397F) ligand binding domain complexed with TEI-9647	3a2j	98.89	no data
704	VDR	Vitamin D3 receptor	P11473	NR1I1	mcz	Human VDR ligand binding domain in complex with maxacalcitol	3b0t	99.14	no data

The Ligandable Human Proteome

Nuclear hormone receptor, ligand-binding domain