The Ligandable Human Proteome

Index	Gene Name Primary	Protein Name	Uniprot ID	Gene Name Synonym	Ligand Name	Structure	PDB Code	ligand desolvation	Compound Affinity nM
1	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		yd3	Crystal structure of human ATAD2 bromodomain in complex with 4-((3R, 4R)-4-3-methyl-5-(5-methylpyridin-3-yl)-2-oxo-1,2-dihydroquinolin-8- yl-aminopiperidin-3-yloxymethyl)-1-thiane-1,1-dione	5a83	64.75	158.
2	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		kw5	Crystal structure of human ATAD2 bromodomain in complex with N-(4-bromo-3-((3-methylpiperidin-1-yl)sulfonyl)phenyl)-2-(2,5-dioxoimidazolidin-1-yl)acetamide	6s55	84.76	no data
3	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		kvz	Crystal structure of human ATAD2 bromodomain in complex with N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)-2-(2,5-dioxo-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalen]-1-yl)acetamide	6s56	62.33	no data
4	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		kvt	Crystal structure of human ATAD2 bromodomain in complex withN-(3-(azepan-1-ylsulfonyl)-4-methylphenyl)-2-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)acetamide	6s57	75.61	no data
5	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g7q	The ATAD2 bromodomain in complex with compound 17	6hie	62.78	no data
6	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g7n	The ATAD2 bromodomain in complex with compound 13	6hia	67.91	no data
7	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g7h	The ATAD2 bromodomain in complex with compound 15	6hic	80.12	no data
8	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g6z	The ATAD2 bromodomain in complex with compound 14	6hib	62.87	no data
9	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g6w	The ATAD2 bromodomain in complex with compound 11	6hi8	67.85	no data
10	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g6e	The ATAD2 bromodomain in complex with compound 8	6hi5	57.04	no data
11	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g6b	The ATAD2 bromodomain in complex with compound 10	6hi7	61.7	no data
12	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g5z	The ATAD2 bromodomain in complex with compound 9	6hi6	65.23	no data
13	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g5w	The ATAD2 bromodomain in complex with compound 7	6hi4	69.47	no data
14	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		g1e	The ATAD2 bromodomain in complex with compound 12	6ept	65.44	no data
15	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		fzh	Crystal structure of human ATAD2 bromodomain in complex with 8-(((1R,2R,3R,5S)-2-(2-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)quinolin-2(1H)-one	6hdo	60.24	no data
16	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		bqt	The ATAD2 bromodomain in complex with compound 5	6epv	66.43	no data
17	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		bqk	The ATAD2 bromodomain in complex with compound UZH-DQ41	6eps	62.58	no data
18	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		bqh	The ATAD2 bromodomain in complex with compound 2	6epu	67.48	no data
19	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		bqe	The ATAD2 bromodomain in complex with compound UZH-DS15	6epr	66.17	no data
20	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		bq8	The ATAD2 bromodomain in complex with compound UZH-DU32	6epw	64.54	no data
21	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		boh	The ATAD2 bromodomain in complex with compound 6	6epj	67.25	no data
22	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		6xx	Crystal structure of human ATAD2 bromodomain in complex with 8-(((3R,4R,5S)-3-((4,4-difluorocyclohexyl)methoxy)-5-methoxypiperidin-4-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one	5lj0	65.25	10.
23	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		thm	Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymidine	4qsv	68.32	1e+007
24	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		38t	Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 5-methyl uridine	4qsw	71.15	2.1e+007
25	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		38s	Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 3'-deoxy thymidine	4qsx	64.01	1.8e+007
26	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		jtf	Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one	5a5p	62.36	100000.
27	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		6xc	Crystal structure of human ATAD2 bromodomain in complex with 3-methyl- 8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one hydrochloride	5a5q	62.86	21000.
28	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		np8	Crystal structure of human ATAD2 bromodomain in complex with 5-5- methoxypyridin-3-yl-3-methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7- naphthyridin-2-one	5a5r	62.81	1260.
29	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		78j	Crystal structure of human ATAD2 bromodomain in complex with 8-(3R,4R) -3-(cyclohexylmethoxy)piperidin-4-yl-amino-3-methyl-1,2-dihydro-1,7- naphthyridin-2-one	5a81	67.63	2900.
30	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		yej	Crystal structure of human ATAD2 bromodomain in complex with 4-(3R,4R) -4-(3-methyl-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl)aminopiperidin-3- yloxymethyl)-1-thiane-1,1-dione	5a82	71.76	2510.
31	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		5qw	Crystal structure of the bromodomain of human ATAD2 in complex with Compound 49	5epb	64.69	no data
32	ATAD2	ATPase family AAA domain-containing protein 2	Q6PL18		fzb	Crystal structure of human ATAD2 bromodomain in complex with 3-methyl-8-((8-methyl-8-azabicyclooctan-3-yl)amino)-1,7-naphthyridin-2(1H)-one	6hdn	65.06	no data
33	BAZ2A	Bromodomain adjacent to zinc finger domain protein 2A	Q9UIF9	KIAA0314 TIP5	jr4	Crystal Structure of BAZ2A bromodomain in complex with 1,3-dimethyl-benzimidazolone compound 1	5or8	56.64	no data
34	BAZ2A	Bromodomain adjacent to zinc finger domain protein 2A	Q9UIF9	KIAA0314 TIP5	d9b	Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 5	6fgg	47.88	no data
35	BAZ2A	Bromodomain adjacent to zinc finger domain protein 2A	Q9UIF9	KIAA0314 TIP5	6rz	Crystal Structure of BAZ2A bromodomain in complex with 3-amino-2-methylpyridine derivative 1	6fgh	72.91	no data
36	BAZ2A	Bromodomain adjacent to zinc finger domain protein 2A	Q9UIF9	KIAA0314 TIP5	d9k	Crystal Structure of BAZ2A bromodomain in complex with 3-amino-2-methylpyridine derivative 2	6fgi	73.02	no data
37	BAZ2A	Bromodomain adjacent to zinc finger domain protein 2A	Q9UIF9	KIAA0314 TIP5	d9t	Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 3	6fgv	60.41	no data
38	BAZ2A	Bromodomain adjacent to zinc finger domain protein 2A	Q9UIF9	KIAA0314 TIP5	d9q	Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 4	6fgw	55.22	no data
39	BAZ2A	Bromodomain adjacent to zinc finger domain protein 2A	Q9UIF9	KIAA0314 TIP5	en2	Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 2	6fgf	53.85	no data
40	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	2lw	Crystal Structure of the bromodomain of human BAZ2B in complex with compound-6 E11322	4nra	61.62	65000.
41	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	2lx	Crystal Structure of the bromodomain of human BAZ2B in complex with compound-1 N01197	4nrb	67.62	38000.
42	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	54v	Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 314268-40-1 (SGC - Diamond I04-1 fragment screening)	5cub	50.53	no data
43	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	6rr	Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 2	5l8t	76.51	279000.
44	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	6rs	Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 5	5l8u	75.17	no data
45	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	6rw	Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 3	5l97	73.77	1e+006
46	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	6ry	Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 4	5l98	74.34	490000.
47	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	jr5	Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 13	5or9	59.75	88000.
48	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	jr6	Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 30	5orb	55.17	51000.
49	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	6rz	Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 1	5l96	83.1	500000.
50	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	d9t	Crystal Structure of BAZ2B bromodomain in complex with 1-methylpyridinone compound 3	6fgt	52.27	no data
51	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	d9q	Crystal Structure of BAZ2B bromodomain in complex with 1-methylpyridinone compound 4	6fgu	57.07	no data
52	BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	KIAA1476	en2	Crystal Structure of BAZ2B bromodomain in complex with 1-methylpyridinone compound 2	6fh7	58.92	no data
53	BRD1	Bromodomain-containing protein 1	O95696	BRL BRPF2	8rv	PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10941a	5poj	67.89	no data
54	BRD1	Bromodomain-containing protein 1	O95696	BRL BRPF2	8rv	PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10941a	5pof	64.12	no data
55	BRD1	Bromodomain-containing protein 1	O95696	BRL BRPF2	8uj	PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N11039a	5poz	67.44	no data
56	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	s5b	N-Terminal Bromodomain of Human BRD2 With tbutyl-phenyl-amino- dimethyl-oxazolyl-quinoline-carboxylic acid	4akn	64.17	790.
57	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	jwa	N-terminal bromodomain of human BRD2 with N-((4-(3-(N-cyclopentylsulfamoyl)-4-methylphenyl)-3-methylisoxazol-5-yl)methyl)acetamide inhibitor	6mo7	75.6	no data
58	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	jvy	N-terminal bromodomain of human BRD2 in complex with N-cyclopentyl-7-(3,5-dimethylisoxazol-4-yl)quinoline-5-sulfonamide inhibitor	6mo9	87.84	no data
59	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	hwv	BRD2_Bromodomain2 complex with inhibitor 744	6e6j	82.72	no data
60	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	d7q	Human BRD2 C-terminal bromodomain with 2-((4-acetyl-3-cyclopropyl-3,4-dihydroquinoxalin-1(2H)-yl)methyl)benzoic acid	6ffe	66.63	no data
61	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	d7h	Human BRD2 C-terminal bromodomain with (S)-5-(1-acetyl-2-cyclopropyl-4-(2-(hydroxymethyl)benzyl)-1,2,3,4-tetrahydroquinoxalin-6-yl)pyrimidine-2-carboxamide	6fff	61.77	no data
62	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	d7b	Human BRD2 C-terminal bromodomain with (S)-1-(2-cyclopropyl-4-(2-(hydroxymethyl)benzyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone	6ffg	62.85	no data
63	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	cqf	Crystal structure of BRD2(BD2)with ligand BY27 bound	6k04	65.31	no data
64	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	cqf	Crystal structure of BRD2(BD1)with ligand BY27 bound	6k05	65.39	no data
65	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9s3	N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1-((2R,4S)-2-methyl-4-(phenylamino)-6-(4-(piperidin-1-ylmethyl)phenyl)-3,4-dihydroquinolin-1(2H)-yl)ethanone	4uyh	57.08	500.
66	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	73b	C-Terminal bromodomain of Human BRD2 with I-BET726 (GSK1324726A)	4uyg	61.54	25.
67	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	73b	N-Terminal bromodomain of Human BRD2 with I-BET726 (GSK1324726A)	4uyf	60.43	25.
68	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	2lo	Crystal structure of BRD2 second bromodomain in complex with SGC-CBP30 chemical probe	5bt5	55.09	no data
69	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	wsh	Crystal Structure of the First Bromodomain of Human Brd2 with the inhibitor GW841819X	2ydw	62.95	46.
70	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	eam	Crystal structure of BRD2(BD2) W370F mutant with ligand I-BET 762 bound	5dfc	62.22	no data
71	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	eam	Crystal Structure of the First Bromodomain of Human Brd2 with the inhibitor GSK525762 (IBET)	2yek	65.59	61.3
72	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	1gh	N-Terminal Bromodomain of Human BRD2 With IBET-151	4alg	69.23	500.
73	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	p9m	N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-cyclopentyl-5-(3,5- dimethyl-1,2-oxazol-4-yl)-2-methylbenzene-1-sulfonamide	4a9m	72.11	500.
74	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	jq1	Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor JQ1	3oni	67.13	no data
75	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	1k0	X-ray crystal structure of bromodomain 2 of human brd2 in complex with rvx208 to 1.08 A resolution	4j1p	63.03	90.
76	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	1k0	Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-OH)	4mr5	72.72	251.
77	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	1k0	Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-208)	4mr6	65.91	251.
78	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	5gd	X-ray crystal structure of human BRD2(BD2) in complex with RVX297 to 1.55 A resolution	5dw1	56.87	80.
79	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	5p4	Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline inhibitor	5ek9	69.4	47.
80	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	8j2	Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue	5n2l	86.64	no data
81	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	31o	Crystal structure of BRD2(BD2) mutant with ligand ME bound (METHYL (2R)- 2-[(4S)-6-(4-CHLOROPHENYL)-8-METHOXY-1-METHYL-4H-[1,2,4]TRIAZOLO[4,3-A][1, 4]BENZODIAZEPIN-4-YL]PROPANOATE)	4qev	66.39	22.
82	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	31o	Human Brd2(BD2) mutant in complex with ME	5o39	65.74	no data
83	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	31p	Crystal structure of BRD2(BD2) mutant with ligand ET bound (METHYL (2R)- 2-[(4S)-6-(4-CHLOROPHENYL)-8-METHOXY-1-METHYL-4H-[1,2,4]TRIAZOLO[4,3-A][1, 4]BENZODIAZEPIN-4-YL]BUTANOATE)	4qew	67.42	86.
84	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	31p	Human Brd2(BD2) mutant in complex with ET	5o3a	74.29	no data
85	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9hz	Human Brd2(BD2) mutant in complex with AL	5o3b	72.02	no data
86	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9j2	Human Brd2(BD2) mutant in complex with 9-Me	5o3c	67.15	no data
87	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9j5	Human Brd2(BD2) mutant in complex with 9-ET	5o3d	70.96	no data
88	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9hw	Human Brd2(BD2) mutant in complex with Me-Am1	5o3e	69.48	no data
89	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9ht	Human Brd2(BD2) mutant in complex with ET-Am1	5o3f	67.2	no data
90	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9j8	Human Brd2(BD2) mutant in complex with AL-Am1	5o3g	66.98	no data
91	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9hq	Human Brd2(BD2) mutant in complex with 9-ME-Am1	5o3h	69.29	no data
92	BRD2	Bromodomain-containing protein 2	P25440	KIAA9001 RING3	9hn	Human Brd2(BD2) mutant in complex with AL-tBu	5o3i	66.57	no data
93	BRD3	Bromodomain-containing protein 3	Q15059	KIAA0043 RING3L	jq1	Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1	3s92	67.73	no data
94	BRD3	Bromodomain-containing protein 3	Q15059	KIAA0043 RING3L	jq1	Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1	3s91	65.29	no data
95	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	x30	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG048	5w55	48.2	no data
96	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	x27	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG056	6cj2	60.19	no data
97	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	uth	The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand	4bw2	62.36	6310.
98	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	s5b	The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand	4bw1	62.3	1260.
99	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	r78	Crystal structure of the first bromodomain of human BRD4 in complex with BI 2536	4o74	45.7	25.
100	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	r78	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor BI-2536	4ogi	70.76	37.
101	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	n1d	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4-dimethoxyphenyl)-2-(4-methanesulfonylpiperazine-1-carbonyl)-5-methyl-4H,5H-thieno-3,2-c- pyridin-4-one	4uiz	58.89	19950.
102	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	loc	Joint nentron and X-ray structure of BRD4 in complex with colchicin	6ajz	62.67	no data
103	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	loc	Crystal structure of the first bromodomain of BRD4 in complex with 18-Crown-6	6in1	63.15	no data
104	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	ksz	Crystal Structure of the first bromodomain of BRD4 in complex with a benzodiazepine ligand	6s25	55.44	no data
105	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	jqy	Crystal structure of the first bromodomain of human BRD4 in complex with SKT-68, a 1,4,5-trisubstituted imidazole analogue	6mh7	70.27	no data
106	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	jqp	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH HU-10, A 1,4,5-Trisubstituted Imidazole Analogue	6mh1	70.25	no data
107	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	jbs	Crystal structure of human BRD4(1) in complex with CN210 (compound 19)	6mau	54.67	no data
108	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	ies	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH I-BET295	4cl9	60.54	50.
109	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	hry	Crystal structure of human BRD4(1) in complex with CN750	6e4a	52.67	no data
110	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	hg8	Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 16k	6q3z	59.53	no data
111	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	hg5	Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 16i	6q3y	56.01	no data
112	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	hcc	Crystal structure of BRD4 in complex with isoliquiritigenin and DMSO (Cocktail No. 3)	6ajv	76.66	no data
113	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	hcc	Crystal structure of BRD4 in complex with isoliquiritigenin in the absence of DMSO	6ajx	69.42	no data
114	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	guj	BRD4 bromodomain 1 in complex with HYB157	6dl2	74.78	no data
115	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	fze	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH : 8-(((1R,2R,3R,5S)-2-(2-(4,4-difluorocyclohexyl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one	6hdq	60.32	no data
116	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	ex1	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG046	6cd4	48.44	no data
117	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	e0k	Crystal Structure Analysis of the BRD4	5yqx	74.08	no data
118	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	dzh	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR #17	6fo5	61.75	no data
119	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	d7t	Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone	6ffd	74.76	no data
120	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	b0q	Crystal structure of human BRD4(1) bromodomain in complex with UT22B	5oww	85.03	no data
121	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	ay2	Crystal structure of human BRD4(1) bromodomain in complex with DR46	5ovb	58.17	no data
122	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	a0r	Crystal structure of BRD4 in complex with 2',4'-dihydroxy-2-methoxychalcone	6ajy	73.08	no data
123	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	9u4	BRD4-BD1 in complex with Cpd19 (3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide)	5vzs	49.58	no data
124	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	9s3	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1-(2R,4S)-2-methyl-4-(phenylamino)-6-4-(piperidin-1-ylmethyl)phenyl-1,2,3,4- tetrahydroquinolin-1-yl-ethan-1-one	5acy	59.13	6.4
125	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	9e3	Crystal Structure of the first bromodomain of human BRD4 in complex with 5-((4-fluoro-1H-imidazol-1-yl)methyl)quinolin-8-ol	6afr	78.29	no data
126	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	9bm	A multiconformer ligand model of 3,5 dimethylisoxaxole bound to the bromodomain of human BRD4	6dml	62.83	no data
127	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	96x	The first bromodomain of BRD4 with compound BDF-1253	5z5v	71.04	no data
128	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8xx	Crystal structure of BRD4-BD1 bound with hjp64	5you	70.27	no data
129	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8xr	Crystal structure of BRD4-BD1 bound with hjp126	5yov	70.14	no data
130	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8q9	Crystal Structure Analysis of the BRD4	5y93	57.45	no data
131	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	79c	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH RO3280	5vbp	77.06	no data
132	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	73b	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH GSK1324726A (I-BET726)	4bjx	63.08	22.
133	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	6xx	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 8-(((3R,4R,5S)-3-((4,4-difluorocyclohexyl)methoxy)-5-methoxypiperidin-4-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one	5lj1	59.71	31600.
134	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	6xw	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-(5-aminopyridin-3-yl)-8-(((3R,4R)-3-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy)piperidin-4-yl)amino)-3-methyl-1,7-naphthyridin-2(1H)-one	5lj2	53.64	10000.
135	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	6tb	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH DB-1-264-2	5kj0	54.68	130.
136	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5w1	Crystal structure of the first bromodomain of human BRD4 in complex with MA4-022-2	5f62	59.56	6.8
137	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5w0	Crystal structure of the first bromodomain of human BRD4 in complex with MA4-022-1	5f61	70.48	35.
138	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5vz	Crystal structure of the first bromodomain of human BRD4 in complex with SG3-014	5f60	58.95	43.
139	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5vy	Crystal structure of the first bromodomain of human BRD4 in complex with MA2-014	5f5z	70.18	86.
140	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	57g	First bromodomain of BRD4 bound to inhibitor XD29	5d3h	64.52	7900.
141	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	53w	A multiconformer ligand model of inhibitor 53W bound to CREB binding protein bromodomain	6dmj	62.7	no data
142	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	4k4	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH LRRK2-IN-1	5vbo	53.53	no data
143	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	4k4	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor XMD11-50	5wa5	47.47	no data
144	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2ta	Crystal structure of the first bromodomain of human BRD4 in complex with TG101348	4ps5	56.6	290.
145	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2ta	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor TG-101348	4ogj	82.1	164.
146	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2lo	Crystal structure of BRD4 first bromodomain in complex with SGC-CBP30 chemical probe	5bt4	48.4	no data
147	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1m3	Crystal structure of the first bromodomain of human BRD4 in complex with TG101209	4o76	84.96	130.
148	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1a9	Brd4 Bromodomain 1 complex with 3-CYCLOHEXYL-N-{3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)-5-[(THIOPHEN-2-YLSULFONYL)AMINO]PHENYL}PROPANAMIDE inhibitor	4hxl	59.02	2200.
149	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	0s6	Crystal structure of the second bromodomain of human BRD4 in complex with MS417 inhibitor	6duv	80.73	no data
150	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	wsh	Crystal Structure of the Second Bromodomain of Human Brd4 with the inhibitor GW841819X	2yem	67.3	15.5
151	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	wsh	Crystal Structure of the First Bromodomain of Human Brd4 with the inhibitor GW841819X	2yel	67.43	52.5
152	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	cpb	Crystal structure of the first bromodomain of human BRD4 in complex with FLAVOPIRIDOL	4o71	88.16	18000.
153	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	eam	Crystal Structure of the First Bromodomain of Human Brd4 in complex with IBET inhibitor	3p5o	68.55	55.2
154	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	wdr	Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand	3svf	69.57	no data
155	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	08h	Crystal Structure of the first bromodomain of human BRD4 in complex with Alprazolam	3u5j	74.8	2460.
156	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	08k	Crystal Structure of the first bromodomain of human BRD4 in complex with a benzo-triazepine ligand (BzT-7)	3u5l	74.59	640.
157	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1gh	Crystal Structure of the first bromodomain of human BRD4 in complex with I-BET151(GSK1210151A)	3zyu	69.2	100.
158	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	p9l	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1,3-DIMETHYL-6-(MORPHOLINE- 4-SULFONYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-2-ONE	4a9l	75.8	no data
159	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	9bm	The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand	4bw3	64.05	500.
160	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	h4c	Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains	4c66	73.32	79400.
161	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	83t	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH IBET-295	4clb	59.79	280.
162	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	jq1	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1	3mxf	66.54	49.
163	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	0q1	Crystal Structure of the first bromodomain of human BRD4 in complex with a isoxazolylbenzimidazole ligand	4gpj	72.04	no data
164	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	14z	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazoline ligand	4hbw	77.81	4800.
165	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	14x	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand	4hbx	75.34	1900.
166	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	13f	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand	4hby	71.19	4400.
167	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1h2	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	4j0r	78.84	386.
168	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1h3	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	4j0s	79.18	382.
169	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1xb	Structure of BRD4 bromodomain 1 with a dimethyl thiophene isoxazole azepine carboxamide	4lrg	68.9	no data
170	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2sj	Crystal Structure of BRD4(1) bound to Colchiceine	4lys	72.8	46000.
171	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	21q	Crystal Structure of BRD4(1) bound to inhibitor XD14	4lyw	62.7	237.
172	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	25k	Crystal Structure of the first bromodomain of human BRD4 in complex with a 5-methyl-triazolopyrimidine ligand	4men	78.15	125000.
173	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1k0	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-OH)	4mr3	61.79	1142.
174	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1k0	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-208)	4mr4	59.19	1142.
175	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1k0	X-ray crystal structure of bromodomain complex to 1.24 A resolution	4j3i	61.36	1800.
176	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2ll	Crystal structure of the first bromodomain of human BRD4 in complex with an isoxazolyl-benzimidazole ligand	4nr8	58.78	no data
177	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	nue	Crystal structure of the first bromodomain of human BRD4 in complex with MS267 inhibitor	4nue	61.9	150.
178	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2re	Crystal structure of the first bromodomain of human BRD4 in complex with SB 202190	4o77	61.42	2500.
179	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	sav	Crystal structure of the first bromodomain of human BRD4 in complex with GW612286X	4o78	71.13	4600.
180	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2rf	Crystal structure of the first bromodomain of human BRD4 in complex with SB-409514	4o7a	74.99	19000.
181	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2rj	Crystal structure of the first bromodomain of human BRD4 in complex with SB-284847-BT	4o7b	74.21	20000.
182	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2rk	Crystal structure of the first bromodomain of human BRD4 in complex with SB-614067-R	4o7c	59.2	10000.
183	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2rq	Crystal structure of the first bromodomain of human BRD4 in complex with SB-251527	4o7f	70.6	13000.
184	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	2n0	Crystal Structure of the first bromodomain of human BRD4 in complex with compound B13	4pce	75.19	7000.
185	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	30m	Crystal structure of the first bromodomain of human BRD4 in complex with Olinone	4qb3	77.21	3400.
186	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	bnj	Brd4 Bromodomain 1 complex with its novel inhibitors	4qr3	66.64	1400.
187	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	bnk	Brd4 Bromodomain 1 complex with its novel inhibitors	4qr4	63.74	250.
188	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	bnm	Brd4 Bromodomain 1 complex with its novel inhibitors	4qr5	64.66	60.
189	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	tvu	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4-dimethoxyphenyl)-N-(1,1-dioxo-1-thian-4-yl)-5-methyl-4-oxo-4H,5H-thieno-3,2-c-pyridine-2- carboxamide	4uix	71.06	50.1
190	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5v2	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide	4uiy	71.39	2510.
191	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	3ot	Direct photocapture of bromodomains using tropolone chemical probes	4whw	61.51	no data
192	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	3p2	Crystal Structure of the first bromodomain of human BRD4 in complex with a novel inhibitor UMB32 (N-TERT-BUTYL-2-[4-(3,5-DIMETHYL-1,2-OXAZOL-4-YL) PHENYL]IMIDAZO[1,2-A]PYRAZIN-3-AMINE)	4wiv	63.1	550.
193	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	3x0	Discovery of benzotriazolo diazepines as orally-active inhibitors of BET bromodomains: Crystal structure of BRD4 with CPI-13	4x2i	75.67	350.
194	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	y80	Crystal structure of human BRD4(1) in complex with 4-[(2E)-3-(4-methoxyphenyl)-2-phenylprop-2-enoyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19a)	4yh3	66.44	26000.
195	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	y81	Crystal structure of human BRD4(1) in complex with 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19d)	4yh4	71.42	26000.
196	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	4ld	BRD4 bromodomain 2 in complex with gamma-carboline-containing compound, number 18.	4z93	68.46	44.6
197	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	4v1	Crystal structure of hBRD4 in complex with BL-BI06 reveals a novel synthesized inhibitor that induces Beclin1-independent/ATG5-dependent autophagic cell death in breast cancer	4zw1	69.22	no data
198	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	np8	NN-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-5-methoxypyridin-3-yl-3- methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one	5a5s	66.19	1260.
199	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	78j	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 8-(3R,4R)-3-(cyclohexylmethoxy)piperidin-4-ylamino-3-methyl-1,2-dihydro-1,7- naphthyridin-2-one	5a85	67.8	5010.
200	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	etu	Bivalent binding to BET bromodomains	5ad2	92.22	no data
201	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	4wg	BRD4 in complex with ERK5 inhibitor XMD8-92	5lrq	52.42	no data
202	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	53w	Selective pharmacological inhibition of the CREB binding protein bromodomain regulates inflammatory cytokines in macrophages and RGS4 in neurons	5cfw	62.11	no data
203	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	e0b	Crystal Structure of the first bromodomain of human BRD4 in complex with benzo[cd]indol-2(1H)-one ligand	5d0c	70.52	2340.
204	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	l26	First bromodomain of BRD4 bound to inhibitor XD26	5d24	77.64	5800.
205	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	56m	First bromodomain of BRD4 bound to inhibitor XD27	5d25	67.37	500.
206	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	l28	First bromodomain of BRD4 bound to inhibitor XD28	5d26	62.58	810.
207	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	l33	First bromodomain of BRD4 bound to inhibitor XD33	5d3j	63.76	5700.
208	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	57f	First bromodomain of BRD4 bound to inhibitor XD35	5d3l	58.52	880.
209	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	l40	First bromodomain of BRD4 bound to inhibitor XD40	5d3n	69.53	9200.
210	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	57e	First bromodomain of BRD4 bound to inhibitor XD41	5d3p	70.56	7400.
211	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	57c	First bromodomain of BRD4 bound to inhibitor XD42	5d3r	62.75	no data
212	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	579	First bromodomain of BRD4 bound to inhibitor XD44	5d3s	68.86	1300.
213	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	56y	First bromodomain of BRD4 bound to inhibitor XD47	5d3t	75.53	12000.
214	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5d2	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR N-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carboxamide	5dlx	63.95	2000.
215	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5d1	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-({1-[(3-methylphe methyl]piperidin-4-yl}methyl)butanamide	5dlz	52	1800.
216	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5gd	X-ray crystal structure of human BRD4(BD1) in complex with RVX297 to 1.12 A resolution	5dw2	51.78	1440.
217	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5nq	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 3-Butyl-8-(6-butyl-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylsulfanylmethyl)-7-ethyl-3,7-dihydropurine-2,6-dione	5egu	62.31	1400.
218	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5nv	First domain of human bromodomain BRD4 in complex with inhibitor 8-(5-Amino-1H-[1,2,4]triazol-3-ylsulfanylmethyl)-3-(4-chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione	5ei4	77.34	26400.
219	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5ou	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 3-(4-Chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione	5eis	78.21	1800.
220	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	loc	Crystal Structure of BRD4(1) bound to Colchicine	4lzr	63.01	20000.
221	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5w4	Crystal structure of the first bromodomain of human BRD4 in complex with PNZ5 isoxazole inhibitor	5fbx	72.38	no data
222	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	rmr	Trimethoxy-ring inhibitor in complex with the first bromodomain of BRD4	5h21	73.17	6400.
223	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	62g	Crystal structure of the first bromodomain of human BRD4 bound to CPI-0610	5hls	70.95	39.
224	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	62v	Crystal structure of the first bromodomain of human BRD4 bound to benzoisoxazoloazepine 3	5hm0	75.24	440.
225	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	64s	Crystal structure of fragment bound with Brd4	5hq7	76.35	no data
226	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	69g	BRD4 in complex with Cpd4 ((E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide)	5i88	75.22	250.
227	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	bmf	Crystal structure of the first bromodomain of human BRD4 in complex with bromosporine (BSP)	5igk	72.05	41.8
228	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	6rx	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH A DIHYDROPYRIDOPYRIMIDINE SCAFFOLD INHIBITOR	5kdh	70.32	no data
229	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	6xh	BRD4 bromodomain in complex with Cpd59 ((S)-1-(3-((2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-1-(tetrahydrofuran-3-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone)	5ku3	58.11	13000.
230	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	1qk	Crystal structure of the first bromodomain of human BRD4 in complex with DINACICLIB	4o70	78.29	19000.
231	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	77x	Structure of the first bromodomain of BRD4 with a pyrazolo[4,3-c]pyridin fragment	5luu	76.71	8630.
232	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	7e7	Crystal structure of BRD4 BROMODOMAIN 1 IN COMPLEX WITH LIGAND 2	5m3a	71.48	2000.
233	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	rnk	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 4-chloro-2-methyl-5-(((3-methylthiophen-2-yl)methyl)amino)pyridazin-3(2H)-one	5mkz	78.29	no data
234	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8j2	Crystal structure of the first bromodomain of human BRD4 in complex with a tetrahydroquinoline analogue	5n2m	67.04	no data
235	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	08j	Crystal Structure of the first bromodomain of human BRD4 in complex with Midazolam	3u5k	71.48	no data
236	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	837	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535	5u2e	62.11	277.
237	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	82y	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2558HA	5u2f	61.45	193.
238	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	87g	BRD4_BD2_A-1395017	5ueo	81.18	no data
239	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	87m	BRD4_BD2_A-1390146	5ueq	81.98	no data
240	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	87p	BRD4_BD2_A-1359930	5uer	82.33	no data
241	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	87s	BRD4_BD2_A-1344772	5ues	70.39	no data
242	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	0s6	Crystal structure of the first bromodomain of human BRD4 in complex with MS417 inhibitor	4f3i	67.09	36.1
243	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	0s6	BRD4_BD2_A-1107604	5ueu	66.38	16.7
244	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	89d	BRD4_BD2_A-1497627	5uex	78.47	1.5
245	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	88m	BRD4_BD2_A-1412838	5uey	77.88	5.1
246	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	89g	BRD4_BD2_A-1342843	5uez	73.45	970.
247	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	89j	BRD4_BD2-A-35165	5uf0	75.75	160000.
248	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	5mj	Crystal Structure of the First Bromodomain of Human BRD4 in Complex With Cyclic Vinylogous Amide Inhibitor MS402	5ula	56.2	77.
249	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8nv	BRD4_BD2_A-1454056	5uvt	77.26	no data
250	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8o4	BRD4_BD2_A-1461028	5uvu	76.81	no data
251	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8ns	BRD4 Bromodomain 2 with A-1457066	5uvv	77.1	no data
252	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8ng	BRD4_Bromodomain1-A1376855	5uvw	87.95	no data
253	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8nj	BRD4 Bromodomain 2 with A-1349391	5uvy	71.46	no data
254	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	9gy	Benzopiperazine BET bromodomain inhibitor in complex with BD1 of Brd4	5vom	65.48	790.
255	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	6je	N-terminal bromodomain of BRD4 in complex with OTX-015	5wmd	58.19	no data
256	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	6jf	N-terminal bromodomain of BRD4 in complex with OTX-015	5wmg	71.6	no data
257	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	7uu	Complex structure of the first bromodomain of BRD4 with an inhibitor that containing a 2H-chromen-2-one ring	5wuu	73.85	810.
258	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8f9	BRD4 bound with compound Bdi2	5xi2	70.56	no data
259	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8f6	BRD4 bound with compound Bdi3	5xi3	72.71	no data
260	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	8f0	BRD4 bound with compound Bdi4	5xi4	70.34	no data
261	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	eo1	BRD4 BD2 in complex with compound CE277	6c7q	65.23	no data
262	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	eo4	BRD4 BD1 in complex with compound CF53	6c7r	66.76	no data
263	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	fp7	BRD4(BD1) complexed with 3219	6czu	73.5	no data
264	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	foy	BRD4(BD1) complexed with 2759	6czv	75.41	no data
265	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	dyz	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR F1	6fnx	78.19	no data
266	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	e5q	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	6fsy	77.45	no data
267	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	e5t	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	6ft3	77.76	no data
268	BRD4	Bromodomain-containing protein 4	O60885	HUNK1	e5w	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	6ft4	72.84	no data
269	BRD7	Bromodomain-containing protein 7	Q9NPI1	BP75 CELTIX1	5u6	Crystal structure of the BRD7 bromodomain in complex with BI-9564	5mq1	75.53	no data
270	BRD9	Bromodomain-containing protein 9	Q9H8M2		n1d	BROMODOMAIN OF HUMAN BRD9 WITH 7-(3,4-dimethoxyphenyl)-2-(4- methanesulfonylpiperazine-1-carbonyl)-5-methyl-4H,5H-thieno-3,2-c- pyridin-4-one	4uit	65.09	200.
271	BRD9	Bromodomain-containing protein 9	Q9H8M2		6b2	Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe	5ign	65.54	no data
272	BRD9	Bromodomain-containing protein 9	Q9H8M2		67c	BRD9 bromodomain in complex with 3-(6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide	6bqa	71.21	no data
273	BRD9	Bromodomain-containing protein 9	Q9H8M2		xzb	BROMODOMAIN OF HUMAN BRD9 WITH N-(1,1-dioxo-1-thian-4-yl)-5-methyl-4- oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c-pyridine-2- carboximidamide	4uiv	66.41	15.8
274	BRD9	Bromodomain-containing protein 9	Q9H8M2		h1b	BROMODOMAIN OF HUMAN BRD9 WITH N-(1,1-dioxo-1-thian-4-yl)-5-ethyl-4- oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c-pyridine-2- carboximidamide	4uiw	67.27	50.
275	BRD9	Bromodomain-containing protein 9	Q9H8M2		tvu	BROMODOMAIN OF HUMAN BRD9 WITH 7-(3,4-dimethoxyphenyl)-N-(1,1-dioxo-1- thian-4-yl)-5-methyl-4-oxo-4H,5H-thieno-3,2-c-pyridine-2-carboxamide	4uiu	67.94	12.6
276	BRD9	Bromodomain-containing protein 9	Q9H8M2		5sw	CRYSTAL STRUCTURE OF BRD9 IN COMPLEX WITH BI-7273	5eu1	70.43	15.4
277	BRD9	Bromodomain-containing protein 9	Q9H8M2		5u2	Crystal structure of the bromodomain of BRD9 in complex with compound 9.	5f1l	74.89	21.
278	BRD9	Bromodomain-containing protein 9	Q9H8M2		5ty	Crystal structure of the BRD9 bromodomain in complex with compound 3.	5f2p	79.06	37500.
279	BRD9	Bromodomain-containing protein 9	Q9H8M2		69g	BRD9 in complex with Cpd4 ((E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide)	5i7y	69.86	52.
280	BRD9	Bromodomain-containing protein 9	Q9H8M2		bmf	Crystal structure of the bromodomain of human BRD9 in complex with bromosporine (BSP)	5igm	71.61	41.7
281	BRD9	Bromodomain-containing protein 9	Q9H8M2		i0d	BROMODOMAIN OF HUMAN BRD9 WITH 4-chloro-2-methyl-5-((2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)amino)pyridazin-3(2H)-one	5mky	77.66	no data
282	BRD9	Bromodomain-containing protein 9	Q9H8M2		5u6	Crystal structure of the BRD9 bromodamian in complex with BI-9564.	5f1h	73.03	14.1
283	BRDT	Bromodomain testis-specific protein	Q58F21		r78	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRDT IN COMPLEX WITH BI2536	5vbq	54.75	no data
284	BRDT	Bromodomain testis-specific protein	Q58F21		jq1	Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor JQ1	4flp	65.44	190.1
285	BRDT	Bromodomain testis-specific protein	Q58F21		1qk	BRDT in complex with Dinaciclib	4kcx	62.86	37000.
286	BRPF1	Peregrin	P55201	BR140	9f9	BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-dimethyl-2-oxo-6-(piperidin-1- yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl-2-methoxybenzamide	4uye	67.66	9.54
287	BRPF1	Peregrin	P55201	BR140	5gv	Crystal structure of the human BRPF1 bromodomain in complex with SEED5	5dya	81.83	200000.
288	BRPF1	Peregrin	P55201	BR140	5sb	Crystal structure of the human BRPF1 bromodomain in complex with SEED15	5ev9	67.77	no data
289	BRPF1	Peregrin	P55201	BR140	5s9	Crystal structure of the human BRPF1 bromodomain in complex with SEED16	5eva	71.8	200000.
290	BRPF1	Peregrin	P55201	BR140	5sk	Crystal structure of the human BRPF1 bromodomain in complex with SEED21	5eww	66.1	no data
291	BRPF1	Peregrin	P55201	BR140	5xf	Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe	5fg5	68.42	no data
292	BRPF1	Peregrin	P55201	BR140	lf1	BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-dimethyl-6-2R-2- methylpiperazin-1-yl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl-2- methoxybenzamide	5g4r	66.19	no data
293	BRPF1	Peregrin	P55201	BR140	8vi	BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-dimethyl-6-2R-2- methylpiperazin-1-yl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl-N- ethyl-2-methoxybenzamide	5g4s	60.66	no data
294	BRPF1	Peregrin	P55201	BR140	bmf	Crystal structure of the human BRPF1 bromodomain in complex with Bromosporine	5c7n	63.59	270.
295	BRPF1	Peregrin	P55201	BR140	uwx	Crystal structure of the human BRPF1 bromodomain in complex with BZ089	5mwh	61.74	no data
296	BRPF1	Peregrin	P55201	BR140	kgu	Crystal structure of the human BRPF1 bromodomain in complex with BZ073	5mwz	57.17	no data
297	BRPF1	Peregrin	P55201	BR140	9l5	Crystal structure of the human BRPF1 bromodomain in complex with BZ047	5o55	62.42	no data
298	BRPF1	Peregrin	P55201	BR140	9ln	Crystal structure of the human BRPF1 bromodomain in complex with BZ032	5o5a	63.71	no data
299	BRPF1	Peregrin	P55201	BR140	9lt	Crystal structure of the human BRPF1 bromodomain in complex with BZ038	5o5f	57.02	no data
300	BRPF1	Peregrin	P55201	BR140	9lk	Crystal structure of the human BRPF1 bromodomain in complex with BZ053	5o5h	70.22	no data
301	BRPF1	Peregrin	P55201	BR140	axn	Crystal structure of the human BRPF1 bromodomain in complex with BZ097	5ov8	60.98	no data
302	BRPF1	Peregrin	P55201	BR140	b0h	Crystal structure of the human BRPF1 bromodomain complexed with BZ054 in space group C2	6ekq	65.92	no data
303	BRPF1	Peregrin	P55201	BR140	b0h	Crystal structure of the human BRPF1 bromodomain in complex with BZ054	5owa	72.16	no data
304	CBP	CREB-binding protein	Q92793	CBP	bkj	CREBBP bromodomain in complex with Cpd 30 (1-(3-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one)	6alb	63.82	no data
305	CBP	CREB-binding protein	Q92793	CBP	ay2	Crystal structure of CREBBP bromodomain complexd with DR46	6fqt	82.4	no data
306	CBP	CREB-binding protein	Q92793	CBP	9ud	CREBBP Bromodomain in complex with Cpd10 (1-(3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one)	5w0l	63	no data
307	CBP	CREB-binding protein	Q92793	CBP	9u4	CREBBP bromodomain in complex with Cpd19 (3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide)	5w0e	63.66	no data
308	CBP	CREB-binding protein	Q92793	CBP	69b	Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02857790	5i89	74.71	33.
309	CBP	CREB-binding protein	Q92793	CBP	69a	Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02778174	5i86	78.99	530.
310	CBP	CREB-binding protein	Q92793	CBP	5qn	Crystal structure of the bromodomain of human CREBBP in complex with UP39	5eng	57.49	no data
311	CBP	CREB-binding protein	Q92793	CBP	2lo	Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand	4nr7	64.65	no data
312	CBP	CREB-binding protein	Q92793	CBP	2ll	A multiconformer ligand model of an isoxazolyl-benzimidazole ligand bound to the bromodomain of human CREBBP	6dmk	60.96	no data
313	CBP	CREB-binding protein	Q92793	CBP	2lk	Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand	4nr4	87.77	no data
314	CBP	CREB-binding protein	Q92793	CBP	2ln	Crystal structure of the bromodomain of human CREBBP in complex with an oxazepin ligand	4nr6	58.09	no data
315	CBP	CREB-binding protein	Q92793	CBP	2ll	Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand	4nr5	62.65	no data
316	CBP	CREB-binding protein	Q92793	CBP	2o3	Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand	4nyw	74.99	no data
317	CBP	CREB-binding protein	Q92793	CBP	2o4	Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand	4nyx	68.83	no data
318	CBP	CREB-binding protein	Q92793	CBP	ul4	Crystal structure of the bromodomain of human CREBBP in complex with UL04	4tqn	77.53	770.
319	CBP	CREB-binding protein	Q92793	CBP	3ot	BROMO domain of CREB binding protein	4whu	66.13	no data
320	CBP	CREB-binding protein	Q92793	CBP	53w	Selective pharmacological inhibition of the CREB binding protein bromodomain regulates inflammatory cytokines in macrophages and RGS4 in neurons	5cgp	67.7	no data
321	CBP	CREB-binding protein	Q92793	CBP	5qr	Crystal structure of the bromodomain of human CREBBP in complex with UN32	5ep7	68.9	no data
322	CBP	CREB-binding protein	Q92793	CBP	5xs	Crystal structure of the bromodomain of human CREBBP in complex with UO37D	5h85	67.44	no data
323	CBP	CREB-binding protein	Q92793	CBP	68y	Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02773986	5i83	74.6	4100.
324	CBP	CREB-binding protein	Q92793	CBP	6f9	Crystal structure of the bromodomain of human CREBBP in complex with a benzoxazepine compound	5j0d	59.34	134.
325	CBP	CREB-binding protein	Q92793	CBP	6xb	Crystal structure of the bromodomain of human CREBBP bound to pyrazolopiperidine scaffold	5ktu	85.88	620.
326	CBP	CREB-binding protein	Q92793	CBP	6xg	CREBBP bromodomain in complex with Cpd 44 (3-((5-acetyl-1-(cyclopropylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)amino)-N-isopropylbenzamide)	5ktw	65.24	30.
327	CBP	CREB-binding protein	Q92793	CBP	6xh	CREBBP bromodomain in complex with Cpd59 ((S)-1-(3-((2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-1-(tetrahydrofuran-3-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone)	5ktx	67.96	20.
328	CBP	CREB-binding protein	Q92793	CBP	xdm	Crystal structure of the bromodomain of human CREBBP bound to the inhibitor XDM1	5lpj	74.3	10100.
329	CBP	CREB-binding protein	Q92793	CBP	71x	Crystal structure of the bromodomain of human CREBBP bound to the inhibitor XDM3c	5lpl	73.34	12000.
330	CBP	CREB-binding protein	Q92793	CBP	77x	Structure of bromodomain of CREBBP with a pyrazolo[4,3-c]pyridin fragment	5tb6	76.37	1530.
331	CBP	CREB-binding protein	Q92793	CBP	96n	Crystal structure of the human bromodomain of CREBBP bound to the inhibitor XDM4	5nrw	73.86	no data
332	CBP	CREB-binding protein	Q92793	CBP	99e	Crystal structure of the human bromodomain of CREBBP bound to the inhibitor XDM-CBP	5nu3	82.34	230.
333	CBP	CREB-binding protein	Q92793	CBP	9u7	CREBBP Bromodomain in complex with Cpd3 ((S)-1-(3-(6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydrofuran-3-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one)	5w0f	66.09	no data
334	CBP	CREB-binding protein	Q92793	CBP	9ua	CREBBP Bromodomain in complex with Cpd8 (1-(3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydrofuran-3-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one)	5w0i	63.43	no data
335	CBP	CREB-binding protein	Q92793	CBP	9ug	CREBBP Bromodomain in complex with Cpd17 (N,2,7-trimethyl-2,3-dihydro-4H-benzo[b][1,4]oxazine-4-carboxamide)	5w0q	73.75	no data
336	CBP	CREB-binding protein	Q92793	CBP	e0d	Crystal Structure Analysis of the CBP	5xxh	65.54	no data
337	CBP	CREB-binding protein	Q92793	CBP	e3t	Crystal structure of CREBBP bromodomain complexd with PA10	6frf	83.74	no data
338	EP300	Histone acetyltransferase p300	Q09472	P300	2lo	Crystal structure of EP300 bromodomain in complex with SGC-CBP30 chemical probe	5bt3	61.95	no data
339	EP300	Histone acetyltransferase p300	Q09472	P300	xdm	Crystal structure of the bromodomain of human EP300 bound to the inhibitor XDM1	5lpk	86.44	3060.
340	EP300	Histone acetyltransferase p300	Q09472	P300	71y	Crystal structure of the bromodomain of human Ep300 bound to the inhibitor XDM3d	5lpm	81.27	2770.
341	EP300	Histone acetyltransferase p300	Q09472	P300	99e	Crystal structure of the human bromodomain of EP300 bound to the inhibitor XDM-CBP	5nu5	75.3	470.
342	KAT2A	Histone acetyltransferase KAT2A	Q92830	GCN5 GCN5L2	b8o	Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n	6j3p	66.79	no data
343	KAT2A	Histone acetyltransferase KAT2A	Q92830	GCN5 GCN5L2	9st	Bromodomain of Human GCN5 with 4-bromo-2-methyl-5-(((3R,5R)-1-methyl-5-phenylpiperidin-3-yl)amino)pyridazin-3(2H)-one	5mlj	72.49	no data
344	KAT2B	Histone acetyltransferase KAT2B	Q92831	PCAF	b4l	Crystal structure of the human PCAF bromodomain in complex with compound 12	6j3o	82.31	no data
345	KAT2B	Histone acetyltransferase KAT2B	Q92831	PCAF	2lx	Crystal structure of human PCAF bromodomain in complex with compound-D (CPD-D), N-methyl-2-(tetrahydro-2H-pyran-4-yloxy)benzamide	5lvq	81.04	73000.
346	KAT2B	Histone acetyltransferase KAT2B	Q92831	PCAF	5x0	Crystal structure of human PCAF bromodomain in complex with compound BDOMB00091a (compound 14)	5fdz	69.06	6800.
347	KAT2B	Histone acetyltransferase KAT2B	Q92831	PCAF	p2l	Bromodomain of Mouse PCAF with (R)-4-chloro-2-methyl-5-((1-methylpiperidin-3-yl)amino)pyridazin-3(2H)-one	5ml0	85.7	no data
348	PB1	Protein polybromo-1	Q86U86	BAF180 PB1	5xk	Crystal structure of the fifth bromodomain of human PB1 in complex with compound 28	5fh8	80.44	170.
349	PB1	Protein polybromo-1	Q86U86	BAF180 PB1	2xd	Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand	4q0n	82.23	no data
350	PB1	Protein polybromo-1	Q86U86	BAF180 PB1	2xc	Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand	4q0o	68.17	no data
351	PB1	Protein polybromo-1	Q86U86	BAF180 PB1	lu2	Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one	5ii2	90.36	12900.
352	PB1	Protein polybromo-1	Q86U86	BAF180 PB1	5xm	Crystal structure of the fifth bromodomain of human PB1 in complex with compound 10	5fh6	73.69	1200.
353	PB1	Protein polybromo-1	Q86U86	BAF180 PB1	5xl	Crystal structure of the fifth bromodomain of human PB1 in complex with compound 18	5fh7	84.13	137.
354	PB1	Protein polybromo-1	Q86U86	BAF180 PB1	6bk	Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with 2-(3,4-dihydroxyphenyl)-5-hydroxy-4H-chromen-4-one	5iid	88.97	no data
355	PHIP	PH-interacting protein	Q8WWQ0	DCAF14 WDR11	5qd	Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with N-(2,6-Dichlorobenzyl)acetamide (SGC - Diamond I04-1 fragment screening)	5enc	68.53	5e+006
356	SMCA2	Probable global transcription activator SNF2L2	P51531	BAF190B BRM SNF2A SNF2L2	5bw	Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with PFI-3 chemical probe	5dkc	73.68	no data
357	SMCA2	Probable global transcription activator SNF2L2	P51531	BAF190B BRM SNF2A SNF2L2	5c0	Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a hydroxyphenyl propenone inhibitor 17	5dkh	69.74	no data
358	SMCA4	Transcription activator BRG1	P51532	BAF190A BRG1 SNF2B SNF2L4	5bw	Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe	5dkd	70.44	no data
359	TAF1	Transcription initiation factor TFIID subunit 1	P21675	BA2R CCG1 CCGS TAF2A	g9y	TAF1-BD2 in complex with Cpd8 (6-(but-3-en-1-yl)-4-(3-(morpholine-4-carbonyl)phenyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)	6df4	82.21	no data
360	TAF1	Transcription initiation factor TFIID subunit 1	P21675	BA2R CCG1 CCGS TAF2A	g9v	TAF1-BD2 in complex with Cpd27 (6-(but-3-en-1-yl)-4-(1-methyl-6-(morpholine-4-carbonyl)-1H-benzo[d]imidazol-4-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)	6df7	75.56	no data
361	TAF1	Transcription initiation factor TFIID subunit 1	P21675	BA2R CCG1 CCGS TAF2A	69g	TAF1-BD2 bromodomain in complex with (E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide	6bqd	83.93	no data
362	TAF1	Transcription initiation factor TFIID subunit 1	P21675	BA2R CCG1 CCGS TAF2A	67c	Second bromodomain of TAF1 bound to a pyrrolopyridone compound	5i1q	81.35	12.
363	TAF1L	Transcription initiation factor TFIID subunit 1-like	Q8IZX4		bmf	Crystal structure of the second bromodomain of human TAF1L in complex with bromosporine (BSP)	5igl	66.69	42.7
364	TIF1A	Transcription intermediary factor 1-alpha	O15164	RNF82 TIF1 TIF1A	4bv	Crystal structure of TRIM24 PHD-bromodomain complexed with N-{1,3-dimethyl-2-oxo-6-[3-(oxolan-3-ylmethoxy)phenoxy]-2,3-dihydro-1H-1,3-benzodiazol-5-yl}-1-methyl-1H-imidazole-4-sulfonamide (7l)	4ybt	63.96	100.
365	TIF1A	Transcription intermediary factor 1-alpha	O15164	RNF82 TIF1 TIF1A	4bk	Crystal structure of TRIM24 PHD-bromodomain complexed with N-{1,3-dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl}-1,2-dimethyl-1H-imidazole-4-sulfonamide (7g)	4ybs	61.32	57.

The Ligandable Human Proteome

Bromodomain