The Ligandable Human Proteome

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von Willebrand factor, type A

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
1ITALIntegrin alpha-LP20701CD11Ala1X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution1xuo89.269.
2ITALIntegrin alpha-LP20701CD11AbqnLFA-1 I domain bound to inhibitors3bqn88.52.5
3ITALIntegrin alpha-LP20701CD11AbqmLFA-1 I domain bound to inhibitors3bqm86.42no data
4ITALIntegrin alpha-LP20701CD11Aab8X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution1xdg66.8350.
5ITALIntegrin alpha-LP20701CD11A2icCD11a (LFA1) I-domain complexed with BMS-587101 aka 5-[(5S, 9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro [4.4]non-7-yl]methyl]-3-thiophenecarboxylicacid2ica74.9920.
6ITALIntegrin alpha-LP20701CD11A803CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION1cqp79.392400.
7ITAMIntegrin alpha-MP11215CD11B CR3AsimStructural basis for simvastatin competitive antagonism of complement receptor 34xw234.31no data