The Ligandable Human Proteome

Index	Gene Name Primary	Protein Name	Uniprot ID	Gene Name Synonym	Ligand Name	Structure	PDB Code	ligand desolvation	Compound Affinity nM
1	GSTA1	Glutathione S-transferase A1	P08263		eaa	GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH ETHACRYNIC ACID	1gsf	88.97	10000.
2	GSTA2	Glutathione S-transferase A2	P09210	GST2	asd	Glutathione transferase A2-2 in complex with delta-4-andostrene-3-17- dione	2vct	65.16	no data
3	GSTA3	Glutathione S-transferase A3	Q16772		asd	Glutathione transferase A3-3 in complex with glutathione and delta-4- androstene-3-17-dione	2vcv	89.56	no data
4	GSTO1	Glutathione S-transferase omega-1	P78417	GSTTLP28	4gg	Glutathione S-transferase Omega 1 bound to covalent inhibitor C4-10	4yqv	83.39	1950.
5	GSTO1	Glutathione S-transferase omega-1	P78417	GSTTLP28	jr7	Glutathione S-Transferase Omega 1 bound to covalent inhibitor 18	6mhb	87.65	no data
6	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	hql	Crystal structure analysis of human hematopoietic prostaglandin D synthase complexed with HQL-79	2cvd	75.81	800.
7	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	d27	Complex structure of prostaglandin D2 synthase at 2.2A.	2vd0	86.6	11600.
8	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	d28	Complex structure of prostaglandin D2 synthase at 2.25A.	2vd1	86.54	138.
9	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	nzo	Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole	3ee2	78.83	65000.
10	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	kxo	An orally active inhibitor bound at the active site of HPGDS	3kxo	86.61	no data
11	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	7pq	Crystal structure of hH-PGDS with water displacing inhibitor	4ec0	73.14	845.
12	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	9pq	Crystal structure of hH-PGDS with water displacing inhibitor	4edy	81.57	1480.
13	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	0o5	Crystal structure of hH-PGDS with water displacing inhibitor	4edz	85.26	8.26
14	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	0o4	Crystal structure of hH-PGDS with water displacing inhibitor	4ee0	76.57	2.34
15	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	cwc	Complex of human hematopoietic prostagandin D2 synthase (hH-PGDS) in complex with an active site inhibitor.	5ais	82.19	570.
16	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	krx	Complex of human hematopoietic prostagandin D2 synthase (hH-PGDS) in complex with an active site inhibitor.	5aix	89.74	12.
17	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	93c	Crystal structure of hematopoietic prostaglandin D synthase in complex with F092	5ywx	84.15	no data
18	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	ux4	Crystal structure of hematopoietic prostaglandin D synthase in complex with U004	5yx1	83.59	no data
19	HPGDS	Hematopoietic prostaglandin D synthase	O60760	GSTS PGDS PTGDS2	kcd	hPGDS complexed with a quinoline-3-carboxamide	6n4e	85.23	no data

The Ligandable Human Proteome

Glutathione S-transferase, C-terminal