The Ligandable Human Proteome

Index	Gene Name Primary	Protein Name	Uniprot ID	Gene Name Synonym	Ligand Name	Structure	PDB Code	ligand desolvation	Compound Affinity nM
1	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	yze	Crystal structure of human glutamate carboxypeptidase II (GCPII) in a complex with DBIBzL, a urea-based inhibitor	3iww	97.64	11.
2	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	okd	Human glutamate carboxypeptidase II in complex with ARM-M4, urea- based inhibitor	2xej	64.53	1.34
3	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	jrg	X-ray structure of human glutamate carboxypeptidase II in complex with a urea-based inhibitor (A25)	3sjf	98.42	23.
4	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	jb7	Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor	4ngm	86.57	0.0449
5	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	fvw	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor RNA 2-65-1	6h7z	90.89	no data
6	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	2r7	X-ray structure of of human glutamate carboxypeptidase II (GCPII) in a complex with CCIBzL, a urea-based inhibitor N~2~-[(1-carboxycyclopropyl)carbamoyl]-N~6~-(4-iodobenzoyl)-L-lysine	4oc0	97.51	318.
7	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	2qq	X-ray structure of of human glutamate carboxypeptidase II (GCPII) in a complex with CEIBzL, a urea-based inhibitor N~2~-{[(1S)-1-carboxybut-3-yn-1-yl]carbamoyl}-N~6~-(4-iodobenzoyl)-L-lysine	4oc2	98.89	5.3
8	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	2qn	X-ray structure of of human glutamate carboxypeptidase II (GCPII) in a complex with CPIBzL, a urea-based inhibitor N~2~-{[(1S)-1-carboxy-2-(pyridin-4-yl)ethyl]carbamoyl}-N~6~-(4-iodobenzoyl)-L-lysine	4oc4	98.11	105.
9	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	5pu	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a hydroxamate inhibitor JHU242	5ely	81.63	44.
10	FOLH1	Glutamate carboxypeptidase 2	Q04609	FOLH NAALAD1 PSM PSMA	5q1	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a hydroxamate inhibitor JHU241	5d29	88.46	97.

The Ligandable Human Proteome

Peptidase M28