The Ligandable Human Proteome

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Polyketide synthase, ketoreductase domain

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
1FASFatty acid synthaseP49327FASkuaHuman Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 226nna94.37no data
2FASFatty acid synthaseP49327FAS2w4Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and GSK21940694piv89.38no data
3FASFatty acid synthaseP49327FAS4xnStructure of the beta-ketoacyl reductase domain of human fatty acid synthase bound to a spiro-imidazolone inhibitor5c3783.4no data