| Index | Gene Name Primary | Protein Name | Uniprot ID | Gene Name Synonym | Ligand Name | Structure | PDB Code | ligand desolvation | Ligand Structure | Compound Affinity nM |
| 1 | TPH1 | Tryptophan 5-hydroxylase 1 | P17752 | TPH TPRH TRPH | ml0 | Crystal structure of human tryoptophan hydroxylase type 1 with bound LP-533401 and Fe | 3hf8 | 72.85 | | 310. |
| 2 | TPH1 | Tryptophan 5-hydroxylase 1 | P17752 | TPH TPRH TRPH | lx0 | Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE | 3hf6 | 78.27 | | 26. |
| 3 | TPH1 | Tryptophan 5-hydroxylase 1 | P17752 | TPH TPRH TRPH | 6z4 | Tryptophan 5-hydroxylase in complex with inhibitor (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid | 5l01 | 85.2 | | 33. |
| 4 | TPH1 | Tryptophan 5-hydroxylase 1 | P17752 | TPH TPRH TRPH | 6h5 | Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors | 5j6d | 92.87 | | 6. |
| 5 | TPH1 | Tryptophan 5-hydroxylase 1 | P17752 | TPH TPRH TRPH | ml4 | Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193 | 3hfb | 76.54 | | 30. |