The Ligandable Human Proteome

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14-3-3 domain

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
11433S14-3-3 protein sigmaP31947HME1gf8Ternary complex of Estrogen Receptor alpha peptide and 14-3-3 sigma C42 mutant bound to disulfide fragment PPI stabilizer 56hn270.18no data
21433S14-3-3 protein sigmaP31947HME10dvCrystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer Fusicoccin H3ux061.65no data
31433S14-3-3 protein sigmaP31947HME1fw1Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin A aglycone3sml67.11no data
41433S14-3-3 protein sigmaP31947HME10v4Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H4fr365.32no data
51433Z14-3-3 protein zeta/deltaP631045soSmall-molecule stabilization of the 14-3-3/Gab2 PPI interface5exa70.46no data