| Index | Gene Name Primary | Protein Name | Uniprot ID | Gene Name Synonym | Ligand Name | Structure | PDB Code | ligand desolvation | Ligand Structure | Compound Affinity nM |
| 1 | CGAS | Cyclic GMP-AMP synthase | Q8N884 | C6orf150 MB21D1 | lls | human cGAS core domain (K427E/K428E) bound with RU-521 | 6o47 | 88.85 | | no data |
| 2 | CGAS | Cyclic GMP-AMP synthase | Q8N884 | C6orf150 MB21D1 | kkp | CYCLIC GMP-AMP SYNTHASE in complex with compound 16 inhibitor: 7-hydroxy-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide | 6nfg | 73.14 | | no data |
| 3 | CGAS | Cyclic GMP-AMP synthase | Q8N884 | C6orf150 MB21D1 | kkm | CYCLIC GMP-AMP SYNTHASE in complex with compound 20 inhibitor: 7-hydroxy-N-[(2S)-1-hydroxypropan-2-yl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide | 6nfo | 71.54 | | no data |
| 4 | CGAS | Cyclic GMP-AMP synthase | Q8N884 | C6orf150 MB21D1 | jum | human cGAS catalytic domain bound with the inhibitor G108 | 6mju | 73.52 | | no data |
| 5 | CGAS | Cyclic GMP-AMP synthase | Q8N884 | C6orf150 MB21D1 | juj | human cGAS catalytic domain bound with the inhibitor G150 | 6mjw | 74.03 | | no data |