The Ligandable Human Proteome

Small GTPase

Index	Gene Name Primary	Uniprot ID	Protein Name	Gene Name Synonym	PDB codes
1	AGAP2	Q99490	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2	CENTG1 KIAA0167	2bmj 2iwr
2	AGAP3	Q96P47	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3	CENTG3	3ihw
3	ARHGAP35	Q9NRY4	Rho GTPase-activating protein 35	GRF1 GRLF1 KIAA1722 P190A p190ARHOGAP	3c5h
4	CDC42	P60953	Cell division control protein 42 homolog		1a4r 1am4 1an0 1doa 1grn 1gzs 1ki1 1kz7 1kzg 1nf3 2dfk 2ngr 2odb 2qrz 2wm9 2wmn 2wmo 3gcg 3qbv 3vhl 4did 4itr 4js0 4yc7 5c2j 5cjp 5upk
5	DIRAS1	O95057	GTP-binding protein Di-Ras1	GBTS1 RIG	2gf0
6	DIRAS2	Q96HU8	GTP-binding protein Di-Ras2		2erx
7	GEM	P55040	GTP-binding protein GEM	KIR	2cjw 2g3y 2ht6
8	HRAS	P01112	GTPase HRas	HRAS1	121p 1agp 1bkd 1clu 1ctq 1gnp 1gnq 1gnr 1he8 1iaq 1ioz 1jah 1jai 1k8r 1lf0 1lf5 1lfd 1nvu 1nvv 1nvw 1p2s 1p2t 1p2u 1p2v 1plj 1pll 1q21 1qra 1rvd 1wq1 1xcm 1xd2 1xj0 1zvq 1zw6 221p 2c5l 2ce2 2cl0 2cl6 2cl7 2clc 2cld 2evw 2q21 2quz 2rga 2rgb 2rgc 2rgd 2rge 2rgg 2uzi 2vh5 2x1v 3ddc 3i3s 3k8y 3k9l 3k9n 3kkm 3kkn 3kud 3l8y 3l8z 3lbh 3lbi 3lbn 3lo5 3oiu 3oiv 3oiw 3rry 3rrz 3rs0 3rs2 3rs3 3rs4 3rs5 3rs7 3rsl 3rso 3tgp 421p 4dlr 4dls 4dlt 4dlu 4dlv 4dlw 4dlx 4dly 4dlz 4efl 4efm 4efn 4g0n 4k81 4l9s 4l9w 4nyi 4nyj 4q21 4rsg 4uru 4urv 4urw 4urx 4ury 4urz 4us0 4us1 4us2 4xvq 4xvr 521p 5b2z 5b30 5p21 5vbe 5vbz 5wdo 5wdp 5wdq 5wfo 5wfp 5wfq 5wfr 5wpl 5x9s 621p 6amb 6bvi 6bvj 6bvk 6bvl 6bvm 6cuo 6cup 6cur 6d55 6d56 6d59 6d5e 6d5g 6d5h 6d5j 6d5l 6d5m 6d5v 6d5w 6q21 721p 821p 5e95 6dzh 6e6c 6e6p
9	KRAS	P01116	GTPase KRas	KRAS2 RASK2	3gft 4epr 4ept 4epv 4epw 4l8g 4ldj 4lpk 4nmm 4obe 4q01 4ql3 4tq9 4tqa 4wa7 5kyk 5mla 5o2t 5ufe 5ufq 5uk9 5uqw 5us4 5usj 5v71 5v9l 5v9o 5w22 5wha 5whb 5whd 5whe 5wlb 5wpm 5xco 6asa 6ase 6bof 6bp1 6fa2 6god 6gqt 6h46 6h47 6cu6 6e6g 6gj5 6gj6 6gj7 6gj8 6m9w 6mbq 6mbt 6mbu 6mqg 6mqn 6ob2 6ob3 6p0z 6p8y 6quu 6quv 6quw 6qux 6p8w 6p8x 6p8z 6n2j 6n2k 5yy1 4lyh 4lyj 4luc 4lv6 4lyf 5f2e 5v6s 5v6v 5v9u 5yxz 6b0v 6b0y
10	NRAS	P01111	GTPase NRas	HRAS1	3con 5uhv 6e6h 6gqy 6gom 6fa3 4epx 4epy 5oco 6fa1 6fa4
11	RAB10	P61026	Ras-related protein Rab-10		5lpn 5szj
12	RAB11A	P62491	Ras-related protein Rab-11A	RAB11	1oiv 1oiw 1oix 1yzk 2d7c 2gzd 2gzh 2hv8 4c4p 4d0l 4lwz 4lx0 4uj3 4uj5 5c46 5ez5 5jcz
13	RAB11B	Q15907	Ras-related protein Rab-11B	YPT3	2f9l 2f9m 4ojk
14	RAB12	Q6IQ22	Ras-related protein Rab-12		2il1
15	RAB14	P61106	Ras-related protein Rab-14		1z0f 4d0g 4drz
16	RAB18	Q9NP72	Ras-related protein Rab-18		1x3s
17	RAB1A	P62820	Ras-related protein Rab-1A	RAB1	2fol 2wwx 3l0i 3sfv 3tkl 4fmc 4jvs
18	RAB1B	Q9H0U4	Ras-related protein Rab-1B		3jza 3nkv 4i1o 5o74 5szh 5szk
19	RAB21	Q9UL25	Ras-related protein Rab-21	KIAA0118	1yzt 1yzu 1z08 1z0i 2ot3
20	RAB22A	Q9UL26	Ras-related protein Rab-22A	RAB22	1z0j
21	RAB25	P57735	Ras-related protein Rab-25	CATX8	2oil 3tso
22	RAB26	Q9ULW5	Ras-related protein Rab-26		2g6b
23	RAB27A	P51159	Ras-related protein Rab-27A	RAB27	3bc1
24	RAB27B	O00194	Ras-related protein Rab-27B		2f7s
25	RAB28	P51157	Ras-related protein Rab-28		2hxs 3e5h
26	RAB29	O14966	Ras-related protein Rab-7L1	RAB7L1	6hh2
27	RAB2A	P61019	Ras-related protein Rab-2A	RAB2	1z0a
28	RAB30	Q15771	Ras-related protein Rab-30		2ew1
29	RAB31	Q13636	Ras-related protein Rab-31	RAB22B	2fg5
30	RAB32	Q13637	Ras-related protein Rab-32		4cym 4cz2 5oec 5oed 6ff8
31	RAB35	Q15286	Ras-related protein Rab-35	RAB1C RAY	3tw8 6ekk 6if2 6if3
32	RAB38	P57729	Ras-related protein Rab-38		6hdu
33	RAB3B	P20337	Ras-related protein Rab-3B		3dz8
34	RAB3D	O95716	Ras-related protein Rab-3D	GOV RAB16	2gf9
35	RAB43	Q86YS6	Ras-related protein Rab-43	RAB41	2hup
36	RAB4A	P20338	Ras-related protein Rab-4A	RAB4	1yu9 1z0k 2bmd 2bme
37	RAB4B	P61018	Ras-related protein Rab-4B		2o52
38	RAB5A	P20339	Ras-related protein Rab-5A	RAB5	1n6h 1n6i 1n6k 1n6l 1n6n 1n6o 1n6p 1n6r 1r2q 1tu3 1tu4 3mjh
39	RAB5B	P61020	Ras-related protein Rab-5B		2hei
40	RAB6A	P20340	Ras-related protein Rab-6A	RAB6	1yzq 2gil 3bbp 4dkx 5lef
41	RAB6B	Q9NRW1	Ras-related protein Rab-6B		2e9s 2fe4 2ffq
42	RAB7A	P51149	Ras-related protein Rab-7a	RAB7	1t91 1yhn 3law 6iyb
43	RAB8A	P61006	Ras-related protein Rab-8A	MEL RAB8	2fu5 3qbt 3tnf 4lhv 4lhw 5szi
44	RAB9A	P51151	Ras-related protein Rab-9A	RAB9	1wms
45	RAB9B	Q9NP90	Ras-related protein Rab-9B	RAB9L	2ocb
46	RAC1	P63000	Ras-related C3 botulinum toxin substrate 1	TC25	1foe 1g4u 1he1 1hh4 1i4d 1i4l 1i4t 1mh1 1ryf 1ryh 2fju 2h7v 2nz8 2p2l 2vrw 2yin 3bji 3sbd 3sbe 3th5 4gzl 4gzm 4yon 5n6o 5o33 6bc1 1e96
47	RAC2	P15153	Ras-related C3 botulinum toxin substrate 2		1ds6 2w2t 2w2v 2w2x
48	RAC3	P60763	Ras-related C3 botulinum toxin substrate 3		2c2h 2g0n 2ic5 2ov2 2qme
49	RALA	P11233	Ras-related protein Ral-A	RAL	1uad 1zc3 1zc4 2a78 2a9k 2bov
50	RAN	P62826	GTP-binding nuclear protein Ran	ARA24	1i2m 1ibr 1k5d 1qbk 1rrp 3a6p 3ch5 3ea5 3gj0 3gj3 3gj4 3gj5 3gj6 3gj7 3gj8 3gjx 3nbz 3nc0 4gmx 4gpt 4hat 4hau 4hav 4haw 4hax 4hay 4haz 4hb0 4hb2 4hb3 4hb4 4ol0 4wvf 5ciq 5cit 5ciw 5cj2 5cll 5dh9 5dha 5dhf 5di9 5dif 5dis 5jlj 5uwh 5uwi 5uwj 5uwo 5uwp 5uwq 5uwr 5uws 5uwt 5uwu 5uww 5yro 5yst 5ysu 5ytb 5yu6 5zpu 6cit 6q82 6a38 6a3a 6a3b 6a3c 6a3e
51	RAP1A	P62834	Ras-related protein Rap-1A	KREV1	1c1y 1gua 3kuc 4kvg
52	RAP1B	P61224	Ras-related protein Rap-1b		3cf6 4dxa 4hdo 4hdq 4mgi 4mgk 4mgy 4mgz 4mh0 5kho
53	RAP2A	P10114	Ras-related protein Rap-2a		1kao 2rap 3rap
54	RASEF	Q8IZ41	Ras and EF-hand domain-containing protein	RAB45	2p5s
55	RASL12	Q9NYN1	Ras-like protein family member 12	RIS	3c5c
56	REM1	O75628	GTP-binding protein REM 1	GES REM	2nzj
57	REM2	Q8IYK8	GTP-binding protein REM 2		3cbq
58	RERG	Q96A58	Ras-related and estrogen-regulated growth inhibitor		2atv
59	RHEB	Q15382	GTP-binding protein Rheb	RHEB2	1xtq 1xtr 1xts 3sea 3t5g 5yxh 6bsx 6bt0
60	RHEBL1	Q8TAI7	GTPase RhebL1		3oes
61	RHOA	P61586	Transforming protein RhoA	ARH12 ARHA RHO12	1a2b 1cxz 1dpf 1ftn 1kmq 1lb1 1ow3 1s1c 1tx4 1xcg 3kz1 3lw8 3lwn 3lxr 3msx 3t06 4d0n 4xh9 4xoi 4xsg 4xsh 5a0f 5bwm 5c2k 5c4m 5ez6 5fr1 5hpy 5irc 5jhg 5jhh 5m6x 5m70 6bc0 6bca 6bcb 6r3v
62	RHOB	P62745	Rho-related GTP-binding protein RhoB	ARH6 ARHB	2fv8 6hxu 6sge
63	RHOC	P08134	Rho-related GTP-binding protein RhoC	ARH9 ARHC	1z2c 2gcn 2gco 2gcp
64	RHOD	O00212	Rho-related GTP-binding protein RhoD	ARHD	2j1l
65	RHOQ	P17081	Rho-related GTP-binding protein RhoQ	ARHQ RASL7A TC10	2atx
66	RHOT1	Q8IXI2	Mitochondrial Rho GTPase 1	ARHT1	5kso 5ksp 5ksy 6d71
67	RHOU	Q7L0Q8	Rho-related GTP-binding protein RhoU	ARHU CDC42L1 G28K WRCH1	2q3h
68	RIT1	Q92963	GTP-binding protein Rit1	RIBB RIT ROC1	4klz
69	RND1	Q92730	Rho-related GTP-binding protein Rho6	RHO6	2cls 2rex 3q3j
70	RND3	P61587	Rho-related GTP-binding protein RhoE	ARHE RHO8 RHOE	1m7b
71	RRAD	P55042	GTP-binding protein RAD	RAD	2dpx 2gjs 3q72 3q7p 3q7q
72	RRAS	P10301	Ras-related protein R-Ras		2fn4
73	RRAS2	P62070	Ras-related protein R-Ras2	TC21	2ery