The Ligandable Human Proteome

Home

Nuclear hormone receptor, ligand-binding domain

IndexGene NameProtein NameDrugsPDB Code
1VDRVitamin D3 receptorCalcitriol3m7r, 1db1, 1ie9, 3a78
2PPARGPeroxisome proliferator-activated receptor gammaTelmisartan,Rosiglitazone,Mifepristone,Pioglitazone,Indometacin3vn2, 6md4, 3qt0, 2prg, 1zgy, 5ycp, 4o8f, 5ji0, 4ema, 3cs8, 4xld, 1fm6, 2xkw, 4xum, 3adx, 3ads, 5y2o
3ANDRAndrogen receptorLiothyronine,Levothyroxine,Fludrocortisone,Betamethasone,Dexamethasone,Testosterone2piw, 1gs4, 3zqt, 2yhd, 4hlw, 2am9, 2ylp, 2ylq, 2ylo, 2q7l, 2q7i, 2q7k, 2q7j
4THBThyroid hormone receptor betaLiothyronine,Levothyroxine3gws, 1xzx
5RXRARetinoic acid receptor RXR-alphaTretinoin,Isotretinoin,Bexarotene,Alitretinoin2acl, 3fal, 3fc6, 3h0a, 4k6i, 1fby, 6a5z, 6a5y, 1xls, 1k74, 5ji0, 3oap, 1xdk, 3uvv, 1fm9, 1fm6
6RARGRetinoic acid receptor gammaTretinoin,Isotretinoin,Alitretinoin2lbd, 5m24, 3lbd
7RARBRetinoic acid receptor betaTretinoin,Isotretinoin,Alitretinoin4dm8, 1xdk
8RARARetinoic acid receptor alphaTretinoin,Isotretinoin3a9e
9ESR1Estrogen receptorRaloxifene,Estradiol,Diethylstilbestrol,Lasofoxifene,Bazedoxifene,Estrone,Estriol2qxs, 1err, 6pit, 4zn7, 3erd, 2ouz, 4xi3, 3hm1, 3q95, 4pxm, 6cbz, 2ocf, 1gwr, 5hyr, 1a52, 1pcg, 3uud, 5wgq, 5gs4, 5gtr, 1qkt, 5dx3, 5dxb, 5dxe, 5dxg, 1g50, 2yja, 5wgd
10PRGRProgesterone receptorMometasone furoate,Mifepristone,Levonorgestrel,Norethisterone,Progesterone,Etonogestrel,Norgestrel1sr7, 2w8y, 1sqn, 1a28, 3d90
11GCRGlucocorticoid receptorMometasone furoate,Fluticasone furoate,Mifepristone,Dexamethasone,Betamethasone,Fluorometholone,Triamcinolone,Fludrocortisone,Hydrocortisone,Methylprednisolone,Tixocortol4p6w, 3cld, 5uc3, 3h52, 1nhz, 4udc, 1p93, 1m2z, 4p6x
12NR1H4Bile acid receptorChenodeoxycholic acid,Ursodeoxycholic acid,Obeticholic acid,chenodeoxycholic acid6hl1, 1ot7, 1osv, 4qe6
13ERR3Estrogen-related receptor gammaDiethylstilbestrol,Cholic Acid,Deoxycholic acid,Ursodeoxycholic acid,Obeticholic acid,Chenodeoxycholic acid1s9p, 1s9q
14RORANuclear receptor ROR-alphaCholesterol1n83
15MCRMineralocorticoid receptorProgesterone,Spironolactone,Dexamethasone,Betamethasone,Fluorometholone,Triamcinolone,Fludrocortisone2aa6, 2aa5, 1ya3, 3vhu, 2ab2, 2oax, 4uda
16ESR2Estrogen receptor betaEstriol,Estradiol2j7y, 4j26, 2j7x, 3ols, 3oll, 4j24, 5toa
17PPARDPeroxisome proliferator-activated receptor deltaIloprost3sp9
18PPARAPeroxisome proliferator-activated receptor alphaIloprost3sp6
19NR1I2Nuclear receptor subfamily 1 group I member 2Ethinylestradiol4x1g, 4x1f