| Index | Gene Name | Protein Name | Drugs | PDB Code |
|---|---|---|---|---|
| 1 | PDE5A | cGMP-specific 3',5'-cyclic phosphodiesterase | Vardenafil,Tadalafil | 3b2r, 1uho, 1udu |
| 2 | PDE4B | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Vardenafil,Roflumilast | 1xot, 1xmu |
| 3 | PDE4D | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Roflumilast,Papaverine | 1xoq, 3g4l, 3iak |
| 4 | PDE10 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Papaverine | 2wey |
| 5 | PDE4A | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Pentoxifylline | 3tvx |