The Ligandable Human Proteome

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Protein kinase domain

IndexGene NameTarget Name
1AAK1Adaptor-associated kinase 1 (AAK1)
2AAPK1AMP-activated protein kinase (AMPK)
3ACVL1Activin receptor-like kinase-1 (ACVRL1)
4AKT1RAC-alpha serine/threonine-protein kinase (AKT1)
5AKT2Phosphorylated protein kinase B (pAKT)
6AKT3Phosphorylated protein kinase B (pAKT)
7ANPRBAtrial natriuretic peptide receptor B (NPR2)
8ARAFA-Raf messenger RNA (ARAF mRNA)
9AURKAAurora kinase A (AURKA)
10AURKBAurora B messenger RNA (AURKB mRNA)
11AURKCAurora kinase C (AURKC)
12AVR2AActivin receptor type IIA (ACVR2A)
13BRAFSerine/threonine-protein kinase Raf (RAF)
14CDC7CDC7-related kinase (CDC7)
15CDK1Cyclin-dependent kinase 1 (CDK1)
16CDK2Cyclin-dependent kinase 2 (CDK2)
17CDK3Cyclin-dependent kinase 3 (CDK3)
18CDK7Cyclin-dependent kinase 7 (CDK7)
19CDK9Cyclin-dependent kinase 9 (CDK9)
20CHK1Checkpoint kinase-1 (CHK1)
21CHK2Serine/threonine-protein kinase Chk2 (RAD53)
22CSF1RMacrophage colony-stimulating factor 1 receptor (CSF1R)
23CSK21Casein kinase II alpha (CSNK2A1)
24DMPKDMPK messenger RNA (DMPK mRNA)
25EGFREpidermal growth factor receptor variant III (EGFR vIII)
26EPHA2Ephrin type-A receptor 2 (EPHA2)
27EPHA3Ephrin type-A receptor 3 (EPHA3)
28EPHB2Ephrin type-B receptor 2 (EPHB2)
29EPHB4Ephrin type-B receptor 4 (EPHB4)
30ERBB2ERBB2 messenger RNA (HER2 mRNA)
31ERBB3Erbb3 tyrosine kinase receptor (Erbb-3)
32FAK1Focal adhesion kinase 1 (FAK)
33FGFR3Fibroblast growth factor receptor 3 (FGFR3)
34FGFR4Fibroblast growth factor receptor 4 (FGFR4)
35GSK3BGlycogen synthase kinase-3 beta (GSK-3B)
36IKKBInhibitor of nuclear factor kappa-B kinase beta (IKKB)
37IRAK4Renal carcinoma antigen NY-REN-64 (IRAK-4)
38ITKT-cell-specific kinase (ITK)
39KCC2ACaM-kinase II (CAMK2)
40KCC2BCaM-kinase II (CAMK2)
41KCC2DCaM-kinase II (CAMK2)
42KCC2GCaM-kinase II (CAMK2)
43KITMutated tyrosine-protein kinase Kit (mKIT)
44KPCBProtein kinase C beta (PRKCB)
45KPCDProtein kinase C delta (PRKCD)
46KPCTProtein kinase C theta (PRKCQ)
47KS6B1Ribosomal protein S6 kinase beta-1 (S6K1)
48KSYKSYK messenger RNA (SYK mRNA)
49LRRK2Leucine-rich repeat kinase 2 (LRRK2)
50LYNTyrosine-protein kinase Lyn (JTK8)
51M3K1MAPK/ERK kinase kinase 1 (MAP3K1)
52M3K2MAPK/ERK kinase kinase 2 (MAP3K2)
53M3K5Apoptosis signal-regulating kinase 1 (MAP3K5)
54M3K9Mixed lineage kinase 1 (MAP3K9)
55MAPK2MAPK-activated protein kinase 2 (MAPKAPK2)
56MARK3Microtubule affinity regulating kinase 3 (MARK3)
57MELKMaternal embryonic leucine zipper kinase (MELK)
58MERTKTyrosine-protein kinase Mer (MERTK)
59MK01Extracellular signal-regulated kinase 2 (ERK2)
60MK03Extracellular signal-regulated kinase 1 (ERK1)
61MK08Stress-activated protein kinase JNK1 (JNK1)
62MK09Jun N terminal kinase (JNK)
63MK10Jun N terminal kinase (JNK)
64MK11Stress-activated protein kinase 2b (p38 beta)
65MK14Stress-activated protein kinase 2a (p38 alpha)
66MKNK1MAPK signal-integrating kinase 1 (MKNK1)
67MKNK2MAP kinase signal-integrating kinase 2 (MKNK2)
68MP2K1ERK activator kinase 1 (MEK1)
69MP2K2ERK activator kinase 2 (MEK2)
70MYLKMyosin light kinase (MYLK)
71PAK4PAK-4 protein kinase (PAK4)
72PDPK1Phosphoinositide dependent protein kinase-1 (PDPK1)
73PIM1Serine/threonine-protein kinase pim-1 (PIM1)
74PIM2Serine/threonine-protein kinase pim-2 (PIM2)
75PKN3Protein kinase N3 (PKN3)
76PLK1PLK1 messenger RNA (PLK1 mRNA)
77PTK6Tyrosine-protein kinase BRK (PTK6)
78PTK7Inactive tyrosine-protein kinase 7 (PTK7)
79RAF1Serine/threonine-protein kinase Raf (RAF)
80RIPK1Receptor-interacting protein 1 (RIPK1)
81RIPK2RIP2 messenger RNA (RIP2 mRNA)
82ROCK2Rho-associated protein kinase 2 (ROCK2)
83RONMacrophage-stimulating protein receptor (RON)
84ROR1Neurotrophic tyrosine kinase ROR1 (ROR1)
85ROR2Neurotrophic tyrosine kinase ROR2 (ROR2)
86SGK1Serine/threonine-protein kinase Sgk1 (SGK1)
87TGFR1TGF-beta receptor type I (TGFBR1)
88TGFR2TGF-beta receptor type II (TGFBR2)
89TIE2Angiopoietin 1 receptor (TEK)
90TTKDual specificity protein kinase TTK (MPS1)
91TYK2TYK2 tyrosine kinase (TYK2)
92VGFR1Vascular endothelial growth factor receptor 1 (FLT-1)
93VGFR3Vascular endothelial growth factor receptor 3 (FLT-4)
94WEE1Wee1-like protein kinase (WEE1)
95YESYes tyrosine kinase (YES)