| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | CERVIX | -1.439 | 3 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | THYROID | -1.809 | 3 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | PLEURA | -1.515 | 7 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | ENDOMETRIUM | -1.625 | 16 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | LIVER | -1.655 | 16 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | GANGLIA | -1.538 | 18 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | KIDNEY | -1.633 | 20 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | STOMACH | -1.64 | 20 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | BONE | -1.714 | 23 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | OESOPHAGUS | -1.553 | 24 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | INTESTINE | -1.534 | 25 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | PANCREAS | -1.551 | 26 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | BREAST | -1.687 | 28 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | SOFT_TISSUE | -1.647 | 31 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | SKIN | -1.654 | 36 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | OVARY | -1.688 | 36 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | SYSTEM | -1.634 | 44 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | TRACT | -1.601 | 53 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.763 | 58 |
| 1 | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 | LUNG | -1.563 | 73 |