The Ligandable Human Proteome

Ubiquitin-conjugating enzyme E2

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	UBE2L3	Ubiquitin-conjugating enzyme E2 L3	CERVIX	-1.005	3
1	UBE2L3	Ubiquitin-conjugating enzyme E2 L3	BONE	-1.027	23
1	UBE2L3	Ubiquitin-conjugating enzyme E2 L3	OESOPHAGUS	-1.013	24
2	UBE2I	SUMO-conjugating enzyme UBC9	CERVIX	-1.164	3
2	UBE2I	SUMO-conjugating enzyme UBC9	PLEURA	-1.171	7
2	UBE2I	SUMO-conjugating enzyme UBC9	LIVER	-1.02	16
2	UBE2I	SUMO-conjugating enzyme UBC9	ENDOMETRIUM	-1.075	16
2	UBE2I	SUMO-conjugating enzyme UBC9	GANGLIA	-1.086	18
2	UBE2I	SUMO-conjugating enzyme UBC9	STOMACH	-1.059	20
2	UBE2I	SUMO-conjugating enzyme UBC9	KIDNEY	-1.109	20
2	UBE2I	SUMO-conjugating enzyme UBC9	BONE	-1.171	23
2	UBE2I	SUMO-conjugating enzyme UBC9	INTESTINE	-1.081	25
2	UBE2I	SUMO-conjugating enzyme UBC9	PANCREAS	-1.076	26
2	UBE2I	SUMO-conjugating enzyme UBC9	BREAST	-1.028	28
2	UBE2I	SUMO-conjugating enzyme UBC9	SOFT_TISSUE	-1.104	31
2	UBE2I	SUMO-conjugating enzyme UBC9	OVARY	-1.04	36
2	UBE2I	SUMO-conjugating enzyme UBC9	SKIN	-1.091	36
2	UBE2I	SUMO-conjugating enzyme UBC9	SYSTEM	-1.046	44
2	UBE2I	SUMO-conjugating enzyme UBC9	TRACT	-1.014	53
2	UBE2I	SUMO-conjugating enzyme UBC9	LUNG	-1.093	73
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	CERVIX	-1.21	3
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	THYROID	-1.423	3
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	PLEURA	-1.201	7
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	ENDOMETRIUM	-1.07	16
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	STOMACH	-1.259	20
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	BONE	-1.39	23
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	OESOPHAGUS	-1.306	24
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	INTESTINE	-1.181	25
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	PANCREAS	-1.156	26
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	BREAST	-1.194	28
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	SOFT_TISSUE	-1.117	31
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	SKIN	-1.187	36
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	OVARY	-1.236	36
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	SYSTEM	-1.182	44
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	TRACT	-1.343	53
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	-1.256	58
3	UBE2N	Ubiquitin-conjugating enzyme E2 N	LUNG	-1.175	73
4	UBE2M	NEDD8-conjugating enzyme Ubc12	THYROID	-1.056	3
4	UBE2M	NEDD8-conjugating enzyme Ubc12	CERVIX	-1.395	3
4	UBE2M	NEDD8-conjugating enzyme Ubc12	LIVER	-1.228	16
4	UBE2M	NEDD8-conjugating enzyme Ubc12	ENDOMETRIUM	-1.511	16
4	UBE2M	NEDD8-conjugating enzyme Ubc12	GANGLIA	-1.218	18
4	UBE2M	NEDD8-conjugating enzyme Ubc12	STOMACH	-1.243	20
4	UBE2M	NEDD8-conjugating enzyme Ubc12	KIDNEY	-1.282	20
4	UBE2M	NEDD8-conjugating enzyme Ubc12	BONE	-1.324	23
4	UBE2M	NEDD8-conjugating enzyme Ubc12	OESOPHAGUS	-1.321	24
4	UBE2M	NEDD8-conjugating enzyme Ubc12	INTESTINE	-1.361	25
4	UBE2M	NEDD8-conjugating enzyme Ubc12	PANCREAS	-1.445	26
4	UBE2M	NEDD8-conjugating enzyme Ubc12	BREAST	-1.289	28
4	UBE2M	NEDD8-conjugating enzyme Ubc12	SOFT_TISSUE	-1.39	31
4	UBE2M	NEDD8-conjugating enzyme Ubc12	SKIN	-1.341	36
4	UBE2M	NEDD8-conjugating enzyme Ubc12	OVARY	-1.352	36
4	UBE2M	NEDD8-conjugating enzyme Ubc12	SYSTEM	-1.246	44
4	UBE2M	NEDD8-conjugating enzyme Ubc12	TRACT	-1.307	53
4	UBE2M	NEDD8-conjugating enzyme Ubc12	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	-1.363	58
4	UBE2M	NEDD8-conjugating enzyme Ubc12	LUNG	-1.389	73