| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | SUPT6H | Transcription elongation factor SPT6 | THYROID | -1.399 | 3 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | CERVIX | -1.581 | 3 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | PLEURA | -1.488 | 7 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | LIVER | -1.629 | 16 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | ENDOMETRIUM | -1.734 | 16 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | GANGLIA | -1.722 | 18 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | STOMACH | -1.616 | 20 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | KIDNEY | -1.633 | 20 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | BONE | -1.555 | 23 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | OESOPHAGUS | -1.583 | 24 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | INTESTINE | -1.595 | 25 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | PANCREAS | -1.542 | 26 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | BREAST | -1.598 | 28 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | SOFT_TISSUE | -1.574 | 31 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | SKIN | -1.616 | 36 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | OVARY | -1.641 | 36 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | SYSTEM | -1.497 | 44 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | TRACT | -1.581 | 53 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.67 | 58 |
| 1 | SUPT6H | Transcription elongation factor SPT6 | LUNG | -1.59 | 73 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | CERVIX | -1.134 | 3 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | THYROID | -1.529 | 3 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | PLEURA | -1.127 | 7 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | LIVER | -1.363 | 16 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | GANGLIA | -1.176 | 18 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | STOMACH | -1.249 | 20 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | KIDNEY | -1.352 | 20 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | OESOPHAGUS | -1.246 | 24 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | SOFT_TISSUE | -1.087 | 31 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | OVARY | -1.072 | 36 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | SYSTEM | -1.224 | 44 |
| 2 | GRB2 | Growth factor receptor-bound protein 2 | TRACT | -1.316 | 53 |