| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | THYROID | -1.122 | 3 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | PLEURA | -1.174 | 7 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | ENDOMETRIUM | -1.013 | 16 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | LIVER | -1.029 | 16 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | GANGLIA | -1.078 | 18 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | KIDNEY | -1.045 | 20 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | BONE | -1.118 | 23 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | INTESTINE | -1.027 | 25 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | PANCREAS | -1.067 | 26 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | SOFT_TISSUE | -1.022 | 31 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | OVARY | -1.091 | 36 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | SKIN | -1.119 | 36 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | SYSTEM | -1.061 | 44 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | TRACT | -1.048 | 53 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.044 | 59 |
| 1 | EIF4E | Eukaryotic translation initiation factor 4E | LUNG | -1.067 | 73 |