| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | NXF1 | Nuclear RNA export factor 1 | CERVIX | -1.078 | 3 |
| 1 | NXF1 | Nuclear RNA export factor 1 | THYROID | -1.082 | 3 |
| 1 | NXF1 | Nuclear RNA export factor 1 | PLEURA | -1.193 | 7 |
| 1 | NXF1 | Nuclear RNA export factor 1 | LIVER | -1.12 | 16 |
| 1 | NXF1 | Nuclear RNA export factor 1 | ENDOMETRIUM | -1.132 | 16 |
| 1 | NXF1 | Nuclear RNA export factor 1 | GANGLIA | -1.084 | 18 |
| 1 | NXF1 | Nuclear RNA export factor 1 | KIDNEY | -1.013 | 20 |
| 1 | NXF1 | Nuclear RNA export factor 1 | STOMACH | -1.116 | 20 |
| 1 | NXF1 | Nuclear RNA export factor 1 | BONE | -1.022 | 23 |
| 1 | NXF1 | Nuclear RNA export factor 1 | OESOPHAGUS | -1.092 | 24 |
| 1 | NXF1 | Nuclear RNA export factor 1 | INTESTINE | -1.122 | 25 |
| 1 | NXF1 | Nuclear RNA export factor 1 | PANCREAS | -1.096 | 26 |
| 1 | NXF1 | Nuclear RNA export factor 1 | BREAST | -1.075 | 28 |
| 1 | NXF1 | Nuclear RNA export factor 1 | SOFT_TISSUE | -1.067 | 31 |
| 1 | NXF1 | Nuclear RNA export factor 1 | SKIN | -1.089 | 36 |
| 1 | NXF1 | Nuclear RNA export factor 1 | OVARY | -1.103 | 36 |
| 1 | NXF1 | Nuclear RNA export factor 1 | SYSTEM | -1.12 | 44 |
| 1 | NXF1 | Nuclear RNA export factor 1 | TRACT | -1.079 | 53 |
| 1 | NXF1 | Nuclear RNA export factor 1 | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.177 | 58 |
| 1 | NXF1 | Nuclear RNA export factor 1 | LUNG | -1.063 | 73 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | CERVIX | -1.573 | 3 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | THYROID | -1.877 | 3 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | PLEURA | -1.617 | 7 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | ENDOMETRIUM | -1.633 | 16 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | LIVER | -1.709 | 16 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | GANGLIA | -1.759 | 18 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | STOMACH | -1.656 | 20 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | KIDNEY | -1.785 | 20 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | BONE | -1.596 | 23 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | OESOPHAGUS | -1.604 | 24 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | INTESTINE | -1.682 | 25 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | PANCREAS | -1.616 | 26 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | BREAST | -1.679 | 28 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | SOFT_TISSUE | -1.647 | 31 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | OVARY | -1.582 | 36 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | SKIN | -1.722 | 36 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | SYSTEM | -1.629 | 44 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | TRACT | -1.592 | 53 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.797 | 58 |
| 2 | LRR1 | Leucine-rich repeat protein 1 | LUNG | -1.649 | 73 |
| 3 | TONSL | Tonsoku-like protein | THYROID | -1.386 | 3 |
| 3 | TONSL | Tonsoku-like protein | CERVIX | -1.408 | 3 |
| 3 | TONSL | Tonsoku-like protein | PLEURA | -1.47 | 7 |
| 3 | TONSL | Tonsoku-like protein | LIVER | -1.311 | 16 |
| 3 | TONSL | Tonsoku-like protein | ENDOMETRIUM | -1.351 | 16 |
| 3 | TONSL | Tonsoku-like protein | GANGLIA | -1.383 | 18 |
| 3 | TONSL | Tonsoku-like protein | STOMACH | -1.261 | 20 |
| 3 | TONSL | Tonsoku-like protein | KIDNEY | -1.35 | 20 |
| 3 | TONSL | Tonsoku-like protein | BONE | -1.409 | 23 |
| 3 | TONSL | Tonsoku-like protein | OESOPHAGUS | -1.297 | 24 |
| 3 | TONSL | Tonsoku-like protein | INTESTINE | -1.337 | 25 |
| 3 | TONSL | Tonsoku-like protein | PANCREAS | -1.345 | 26 |
| 3 | TONSL | Tonsoku-like protein | BREAST | -1.385 | 28 |
| 3 | TONSL | Tonsoku-like protein | SOFT_TISSUE | -1.324 | 31 |
| 3 | TONSL | Tonsoku-like protein | OVARY | -1.292 | 36 |
| 3 | TONSL | Tonsoku-like protein | SKIN | -1.336 | 36 |
| 3 | TONSL | Tonsoku-like protein | SYSTEM | -1.406 | 44 |
| 3 | TONSL | Tonsoku-like protein | TRACT | -1.238 | 53 |
| 3 | TONSL | Tonsoku-like protein | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.351 | 58 |
| 3 | TONSL | Tonsoku-like protein | LUNG | -1.33 | 73 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | CERVIX | -1.384 | 3 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | THYROID | -1.404 | 3 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | PLEURA | -1.45 | 7 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | ENDOMETRIUM | -1.349 | 16 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | LIVER | -1.466 | 16 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | GANGLIA | -1.436 | 18 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | STOMACH | -1.434 | 20 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | KIDNEY | -1.489 | 20 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | BONE | -1.544 | 23 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | OESOPHAGUS | -1.461 | 24 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | INTESTINE | -1.399 | 25 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | PANCREAS | -1.423 | 26 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | BREAST | -1.376 | 28 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | SOFT_TISSUE | -1.423 | 31 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | SKIN | -1.375 | 36 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | OVARY | -1.405 | 36 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | SYSTEM | -1.414 | 44 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | TRACT | -1.376 | 53 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.449 | 58 |
| 4 | RABGGTA | Geranylgeranyl transferase type-2 subunit alpha | LUNG | -1.389 | 73 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | PLEURA | -1.058 | 7 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | ENDOMETRIUM | -1.024 | 16 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | STOMACH | -1.064 | 20 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | OESOPHAGUS | -1.056 | 24 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | INTESTINE | -1.025 | 25 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | PANCREAS | -1.038 | 26 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | BREAST | -1.089 | 28 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | SYSTEM | -1.016 | 44 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.11 | 58 |
| 5 | RANGAP1 | Ran GTPase-activating protein 1 | LUNG | -1.034 | 73 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | CERVIX | -1.609 | 3 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | THYROID | -1.844 | 3 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | PLEURA | -1.591 | 7 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | LIVER | -1.8 | 16 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | ENDOMETRIUM | -1.842 | 16 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | GANGLIA | -1.665 | 18 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | KIDNEY | -1.709 | 20 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | STOMACH | -1.746 | 20 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | BONE | -1.632 | 23 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | OESOPHAGUS | -1.71 | 24 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | INTESTINE | -1.667 | 25 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | PANCREAS | -1.693 | 26 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | BREAST | -1.804 | 28 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | SOFT_TISSUE | -1.841 | 31 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | SKIN | -1.671 | 36 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | OVARY | -1.781 | 36 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | SYSTEM | -1.686 | 44 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | TRACT | -1.669 | 53 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.805 | 58 |
| 6 | SNRPA1 | U2 small nuclear ribonucleoprotein A' | LUNG | -1.619 | 73 |