The Ligandable Human Proteome

Small GTPase

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	RAN	GTP-binding nuclear protein Ran	CERVIX	-2.238	3
1	RAN	GTP-binding nuclear protein Ran	THYROID	-2.456	3
1	RAN	GTP-binding nuclear protein Ran	PLEURA	-2.164	7
1	RAN	GTP-binding nuclear protein Ran	LIVER	-2.297	16
1	RAN	GTP-binding nuclear protein Ran	ENDOMETRIUM	-2.394	16
1	RAN	GTP-binding nuclear protein Ran	GANGLIA	-2.432	18
1	RAN	GTP-binding nuclear protein Ran	KIDNEY	-2.167	20
1	RAN	GTP-binding nuclear protein Ran	STOMACH	-2.3	20
1	RAN	GTP-binding nuclear protein Ran	BONE	-2.351	23
1	RAN	GTP-binding nuclear protein Ran	OESOPHAGUS	-2.334	24
1	RAN	GTP-binding nuclear protein Ran	INTESTINE	-2.218	25
1	RAN	GTP-binding nuclear protein Ran	PANCREAS	-2.304	26
1	RAN	GTP-binding nuclear protein Ran	BREAST	-2.399	28
1	RAN	GTP-binding nuclear protein Ran	SOFT_TISSUE	-2.322	31
1	RAN	GTP-binding nuclear protein Ran	OVARY	-2.34	36
1	RAN	GTP-binding nuclear protein Ran	SKIN	-2.45	36
1	RAN	GTP-binding nuclear protein Ran	SYSTEM	-2.17	44
1	RAN	GTP-binding nuclear protein Ran	TRACT	-2.265	53
1	RAN	GTP-binding nuclear protein Ran	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	-2.609	58
1	RAN	GTP-binding nuclear protein Ran	LUNG	-2.357	73
2	CDC42	Cell division control protein 42 homolog	THYROID	-1.072	3
2	CDC42	Cell division control protein 42 homolog	PLEURA	-1.327	7
2	CDC42	Cell division control protein 42 homolog	LIVER	-1.098	16
2	CDC42	Cell division control protein 42 homolog	ENDOMETRIUM	-1.258	16
2	CDC42	Cell division control protein 42 homolog	GANGLIA	-1.116	18
2	CDC42	Cell division control protein 42 homolog	STOMACH	-1.122	20
2	CDC42	Cell division control protein 42 homolog	KIDNEY	-1.267	20
2	CDC42	Cell division control protein 42 homolog	BONE	-1.106	23
2	CDC42	Cell division control protein 42 homolog	PANCREAS	-1.044	26
2	CDC42	Cell division control protein 42 homolog	BREAST	-1.089	28
2	CDC42	Cell division control protein 42 homolog	SOFT_TISSUE	-1.217	31
2	CDC42	Cell division control protein 42 homolog	SKIN	-1.26	36
2	CDC42	Cell division control protein 42 homolog	OVARY	-1.298	36
2	CDC42	Cell division control protein 42 homolog	SYSTEM	-1.237	44
2	CDC42	Cell division control protein 42 homolog	TRACT	-1.018	53
2	CDC42	Cell division control protein 42 homolog	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	-1.035	59
2	CDC42	Cell division control protein 42 homolog	LUNG	-1.084	73