The Ligandable Human Proteome

Heat shock protein 70 family

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	HYOU1	Hypoxia up-regulated protein 1	CERVIX	-1.145	3
1	HYOU1	Hypoxia up-regulated protein 1	THYROID	-1.315	3
1	HYOU1	Hypoxia up-regulated protein 1	PLEURA	-1.35	7
1	HYOU1	Hypoxia up-regulated protein 1	ENDOMETRIUM	-1.395	16
1	HYOU1	Hypoxia up-regulated protein 1	LIVER	-1.456	16
1	HYOU1	Hypoxia up-regulated protein 1	GANGLIA	-1.408	18
1	HYOU1	Hypoxia up-regulated protein 1	STOMACH	-1.289	20
1	HYOU1	Hypoxia up-regulated protein 1	KIDNEY	-1.47	20
1	HYOU1	Hypoxia up-regulated protein 1	BONE	-1.476	23
1	HYOU1	Hypoxia up-regulated protein 1	OESOPHAGUS	-1.389	24
1	HYOU1	Hypoxia up-regulated protein 1	INTESTINE	-1.31	25
1	HYOU1	Hypoxia up-regulated protein 1	PANCREAS	-1.336	26
1	HYOU1	Hypoxia up-regulated protein 1	BREAST	-1.265	28
1	HYOU1	Hypoxia up-regulated protein 1	SOFT_TISSUE	-1.338	31
1	HYOU1	Hypoxia up-regulated protein 1	OVARY	-1.402	36
1	HYOU1	Hypoxia up-regulated protein 1	SKIN	-1.455	36
1	HYOU1	Hypoxia up-regulated protein 1	SYSTEM	-1.37	44
1	HYOU1	Hypoxia up-regulated protein 1	TRACT	-1.32	53
1	HYOU1	Hypoxia up-regulated protein 1	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	-1.326	58
1	HYOU1	Hypoxia up-regulated protein 1	LUNG	-1.319	73
2	HSPA9	Stress-70 protein, mitochondrial	THYROID	-1.492	3
2	HSPA9	Stress-70 protein, mitochondrial	CERVIX	-1.617	3
2	HSPA9	Stress-70 protein, mitochondrial	PLEURA	-1.555	7
2	HSPA9	Stress-70 protein, mitochondrial	LIVER	-1.547	16
2	HSPA9	Stress-70 protein, mitochondrial	ENDOMETRIUM	-1.586	16
2	HSPA9	Stress-70 protein, mitochondrial	GANGLIA	-1.592	18
2	HSPA9	Stress-70 protein, mitochondrial	KIDNEY	-1.491	20
2	HSPA9	Stress-70 protein, mitochondrial	STOMACH	-1.548	20
2	HSPA9	Stress-70 protein, mitochondrial	BONE	-1.515	23
2	HSPA9	Stress-70 protein, mitochondrial	OESOPHAGUS	-1.524	24
2	HSPA9	Stress-70 protein, mitochondrial	INTESTINE	-1.549	25
2	HSPA9	Stress-70 protein, mitochondrial	PANCREAS	-1.485	26
2	HSPA9	Stress-70 protein, mitochondrial	BREAST	-1.63	28
2	HSPA9	Stress-70 protein, mitochondrial	SOFT_TISSUE	-1.556	31
2	HSPA9	Stress-70 protein, mitochondrial	OVARY	-1.523	36
2	HSPA9	Stress-70 protein, mitochondrial	SKIN	-1.533	36
2	HSPA9	Stress-70 protein, mitochondrial	SYSTEM	-1.563	44
2	HSPA9	Stress-70 protein, mitochondrial	TRACT	-1.482	53
2	HSPA9	Stress-70 protein, mitochondrial	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	-1.582	58
2	HSPA9	Stress-70 protein, mitochondrial	LUNG	-1.53	73
3	HSPA5	Endoplasmic reticulum chaperone BiP	THYROID	-1.125	3
3	HSPA5	Endoplasmic reticulum chaperone BiP	CERVIX	-1.371	3
3	HSPA5	Endoplasmic reticulum chaperone BiP	PLEURA	-1.184	7
3	HSPA5	Endoplasmic reticulum chaperone BiP	ENDOMETRIUM	-1.238	16
3	HSPA5	Endoplasmic reticulum chaperone BiP	LIVER	-1.377	16
3	HSPA5	Endoplasmic reticulum chaperone BiP	GANGLIA	-1.365	18
3	HSPA5	Endoplasmic reticulum chaperone BiP	KIDNEY	-1.24	20
3	HSPA5	Endoplasmic reticulum chaperone BiP	STOMACH	-1.355	20
3	HSPA5	Endoplasmic reticulum chaperone BiP	BONE	-1.301	23
3	HSPA5	Endoplasmic reticulum chaperone BiP	OESOPHAGUS	-1.189	24
3	HSPA5	Endoplasmic reticulum chaperone BiP	INTESTINE	-1.255	25
3	HSPA5	Endoplasmic reticulum chaperone BiP	PANCREAS	-1.266	26
3	HSPA5	Endoplasmic reticulum chaperone BiP	BREAST	-1.294	28
3	HSPA5	Endoplasmic reticulum chaperone BiP	SOFT_TISSUE	-1.311	31
3	HSPA5	Endoplasmic reticulum chaperone BiP	OVARY	-1.334	36
3	HSPA5	Endoplasmic reticulum chaperone BiP	SKIN	-1.345	36
3	HSPA5	Endoplasmic reticulum chaperone BiP	SYSTEM	-1.256	44
3	HSPA5	Endoplasmic reticulum chaperone BiP	TRACT	-1.207	53
3	HSPA5	Endoplasmic reticulum chaperone BiP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	-1.569	58
3	HSPA5	Endoplasmic reticulum chaperone BiP	LUNG	-1.247	73