| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | PCNA | Proliferating cell nuclear antigen | THYROID | -1.702 | 3 |
| 1 | PCNA | Proliferating cell nuclear antigen | CERVIX | -1.99 | 3 |
| 1 | PCNA | Proliferating cell nuclear antigen | PLEURA | -1.801 | 7 |
| 1 | PCNA | Proliferating cell nuclear antigen | LIVER | -1.783 | 16 |
| 1 | PCNA | Proliferating cell nuclear antigen | ENDOMETRIUM | -1.957 | 16 |
| 1 | PCNA | Proliferating cell nuclear antigen | GANGLIA | -1.894 | 18 |
| 1 | PCNA | Proliferating cell nuclear antigen | KIDNEY | -1.762 | 20 |
| 1 | PCNA | Proliferating cell nuclear antigen | STOMACH | -1.878 | 20 |
| 1 | PCNA | Proliferating cell nuclear antigen | BONE | -1.881 | 23 |
| 1 | PCNA | Proliferating cell nuclear antigen | OESOPHAGUS | -1.865 | 24 |
| 1 | PCNA | Proliferating cell nuclear antigen | INTESTINE | -1.855 | 25 |
| 1 | PCNA | Proliferating cell nuclear antigen | PANCREAS | -1.883 | 26 |
| 1 | PCNA | Proliferating cell nuclear antigen | BREAST | -1.939 | 28 |
| 1 | PCNA | Proliferating cell nuclear antigen | SOFT_TISSUE | -1.884 | 31 |
| 1 | PCNA | Proliferating cell nuclear antigen | SKIN | -1.788 | 36 |
| 1 | PCNA | Proliferating cell nuclear antigen | OVARY | -1.848 | 36 |
| 1 | PCNA | Proliferating cell nuclear antigen | SYSTEM | -1.775 | 44 |
| 1 | PCNA | Proliferating cell nuclear antigen | TRACT | -1.802 | 53 |
| 1 | PCNA | Proliferating cell nuclear antigen | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -2.019 | 58 |
| 1 | PCNA | Proliferating cell nuclear antigen | LUNG | -1.878 | 73 |