The Ligandable Human Proteome

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SNF2-related, N-terminal domain

NumberGene NameProtein NamePrimary TissueMedian Essentiality ScoreNumber of Cell Lines
1INO80Chromatin-remodeling ATPase INO80Head and Neck-1.15534
1INO80Chromatin-remodeling ATPase INO80Haematopoietic and Lymphoid-1.12714
1INO80Chromatin-remodeling ATPase INO80Bone-1.10312
1INO80Chromatin-remodeling ATPase INO80Large Intestine-1.05430
1INO80Chromatin-remodeling ATPase INO80Esophagus-1.0126
2SRCAPHelicase SRCAPSkin-1.7994
2SRCAPHelicase SRCAPBone-1.79912
2SRCAPHelicase SRCAPKidney-1.5883
2SRCAPHelicase SRCAPHead and Neck-1.57634
2SRCAPHelicase SRCAPHaematopoietic and Lymphoid-1.46714
2SRCAPHelicase SRCAPCentral Nervous System-1.37633
2SRCAPHelicase SRCAPPeripheral Nervous System-1.27917
2SRCAPHelicase SRCAPStomach-1.21514
2SRCAPHelicase SRCAPOvary-1.16531
2SRCAPHelicase SRCAPLarge Intestine-1.08130
2SRCAPHelicase SRCAPEsophagus-1.04526
3SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5Haematopoietic and Lymphoid-1.83414
3SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5Stomach-1.40314
3SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5Large Intestine-1.3230
3SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5Skin-1.1034