| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Skin | -4.072 | 4 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Bone | -3.458 | 12 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Head and Neck | -3.35 | 34 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Esophagus | -3.335 | 26 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Haematopoietic and Lymphoid | -3.221 | 14 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Large Intestine | -3.164 | 30 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Kidney | -2.975 | 3 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Peripheral Nervous System | -2.801 | 17 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Lung | -2.683 | 42 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Central Nervous System | -2.656 | 33 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Ovary | -2.418 | 31 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Endometrium | -2.338 | 8 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Pancreas | -2.202 | 23 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Stomach | -2.179 | 14 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Prostate | -1.877 | 3 |
| 1 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | Breast | -1.841 | 25 |