The Ligandable Human Proteome

Peptidase C19, ubiquitin carboxyl-terminal hydrolase

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	USP7	Ubiquitin carboxyl-terminal hydrolase 7	Stomach	-1.218	14
1	USP7	Ubiquitin carboxyl-terminal hydrolase 7	Kidney	-1.127	3
1	USP7	Ubiquitin carboxyl-terminal hydrolase 7	Haematopoietic and Lymphoid	-1.081	14
1	USP7	Ubiquitin carboxyl-terminal hydrolase 7	Prostate	-1.055	3
2	USP37	Ubiquitin carboxyl-terminal hydrolase 37	Kidney	-1.79	3
2	USP37	Ubiquitin carboxyl-terminal hydrolase 37	Skin	-1.187	4
2	USP37	Ubiquitin carboxyl-terminal hydrolase 37	Esophagus	-1.173	26
2	USP37	Ubiquitin carboxyl-terminal hydrolase 37	Head and Neck	-1.143	34
2	USP37	Ubiquitin carboxyl-terminal hydrolase 37	Large Intestine	-1.07	30
2	USP37	Ubiquitin carboxyl-terminal hydrolase 37	Lung	-1.067	42
2	USP37	Ubiquitin carboxyl-terminal hydrolase 37	Prostate	-1.024	3
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Skin	-3.028	4
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Haematopoietic and Lymphoid	-3.005	14
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Endometrium	-2.965	8
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Esophagus	-2.964	26
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Large Intestine	-2.949	30
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Head and Neck	-2.862	34
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Pancreas	-2.845	23
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Breast	-2.827	25
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Kidney	-2.711	3
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Bone	-2.703	12
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Stomach	-2.695	14
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Peripheral Nervous System	-2.541	17
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Central Nervous System	-2.505	33
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Ovary	-2.415	31
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Lung	-2.092	42
3	USP39	U4/U6.U5 tri-snRNP-associated protein 2	Prostate	-1.572	3
4	USP10	Ubiquitin carboxyl-terminal hydrolase 10	Kidney	-1.334	3
4	USP10	Ubiquitin carboxyl-terminal hydrolase 10	Skin	-1.268	4
4	USP10	Ubiquitin carboxyl-terminal hydrolase 10	Prostate	-1.188	3
4	USP10	Ubiquitin carboxyl-terminal hydrolase 10	Bone	-1.18	12
4	USP10	Ubiquitin carboxyl-terminal hydrolase 10	Head and Neck	-1.145	34
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Skin	-2.463	4
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Kidney	-2.282	3
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Head and Neck	-2.078	34
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Bone	-2.028	12
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Esophagus	-1.693	26
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Central Nervous System	-1.668	33
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Peripheral Nervous System	-1.568	17
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Stomach	-1.493	14
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Endometrium	-1.454	8
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Lung	-1.412	42
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Haematopoietic and Lymphoid	-1.359	14
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Ovary	-1.239	31
5	USP5	Ubiquitin carboxyl-terminal hydrolase 5	Large Intestine	-1.225	30
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Prostate	-2.196	3
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Haematopoietic and Lymphoid	-1.883	14
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Peripheral Nervous System	-1.732	17
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Large Intestine	-1.716	30
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Kidney	-1.709	3
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Bone	-1.583	12
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Stomach	-1.319	14
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Head and Neck	-1.308	34
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Endometrium	-1.219	8
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Ovary	-1.213	31
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Central Nervous System	-1.183	33
6	USP17L5	Ubiquitin carboxyl-terminal hydrolase 17-like protein 5	Lung	-1.146	42