The Ligandable Human Proteome

Bromodomain

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	TAF1	Transcription initiation factor TFIID subunit 1	Bone	-1.419	12
1	TAF1	Transcription initiation factor TFIID subunit 1	Ovary	-1.418	31
1	TAF1	Transcription initiation factor TFIID subunit 1	Kidney	-1.38	3
1	TAF1	Transcription initiation factor TFIID subunit 1	Haematopoietic and Lymphoid	-1.306	14
1	TAF1	Transcription initiation factor TFIID subunit 1	Large Intestine	-1.255	30
1	TAF1	Transcription initiation factor TFIID subunit 1	Skin	-1.222	4
1	TAF1	Transcription initiation factor TFIID subunit 1	Esophagus	-1.18	26
1	TAF1	Transcription initiation factor TFIID subunit 1	Prostate	-1.176	3
1	TAF1	Transcription initiation factor TFIID subunit 1	Peripheral Nervous System	-1.117	17
1	TAF1	Transcription initiation factor TFIID subunit 1	Head and Neck	-1.115	34
1	TAF1	Transcription initiation factor TFIID subunit 1	Endometrium	-1.11	8
1	TAF1	Transcription initiation factor TFIID subunit 1	Lung	-1.11	42
1	TAF1	Transcription initiation factor TFIID subunit 1	Pancreas	-1.108	23
1	TAF1	Transcription initiation factor TFIID subunit 1	Breast	-1.096	25
2	BRD4	Bromodomain-containing protein 4	Haematopoietic and Lymphoid	-1.432	14
2	BRD4	Bromodomain-containing protein 4	Esophagus	-1.272	26
2	BRD4	Bromodomain-containing protein 4	Kidney	-1.261	3
2	BRD4	Bromodomain-containing protein 4	Head and Neck	-1.177	34
2	BRD4	Bromodomain-containing protein 4	Large Intestine	-1.168	30
2	BRD4	Bromodomain-containing protein 4	Lung	-1.085	42
2	BRD4	Bromodomain-containing protein 4	Central Nervous System	-1.034	33
2	BRD4	Bromodomain-containing protein 4	Pancreas	-1.027	23
2	BRD4	Bromodomain-containing protein 4	Ovary	-1.025	31