The Ligandable Human Proteome

von Willebrand factor, type A

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	INTS6	Integrator complex subunit 6	Large Intestine	-2.992	30
1	INTS6	Integrator complex subunit 6	Skin	-1.689	4
1	INTS6	Integrator complex subunit 6	Breast	-1.176	25
1	INTS6	Integrator complex subunit 6	Pancreas	-1.075	23
2	MDN1	Midasin	Head and Neck	-2.684	34
2	MDN1	Midasin	Bone	-2.458	12
2	MDN1	Midasin	Skin	-2.385	4
2	MDN1	Midasin	Kidney	-2.38	3
2	MDN1	Midasin	Haematopoietic and Lymphoid	-2.183	14
2	MDN1	Midasin	Esophagus	-2.164	26
2	MDN1	Midasin	Central Nervous System	-2.133	33
2	MDN1	Midasin	Prostate	-2.049	3
2	MDN1	Midasin	Stomach	-2.015	14
2	MDN1	Midasin	Endometrium	-1.865	8
2	MDN1	Midasin	Lung	-1.858	42
2	MDN1	Midasin	Peripheral Nervous System	-1.797	17
2	MDN1	Midasin	Large Intestine	-1.785	30
2	MDN1	Midasin	Ovary	-1.774	31
2	MDN1	Midasin	Pancreas	-1.724	23
2	MDN1	Midasin	Breast	-1.355	25
3	GTF2H2C	General transcription factor IIH subunit 2-like protein	Haematopoietic and Lymphoid	-1.697	14
3	GTF2H2C	General transcription factor IIH subunit 2-like protein	Head and Neck	-1.608	34
3	GTF2H2C	General transcription factor IIH subunit 2-like protein	Bone	-1.377	12
3	GTF2H2C	General transcription factor IIH subunit 2-like protein	Large Intestine	-1.311	30
3	GTF2H2C	General transcription factor IIH subunit 2-like protein	Esophagus	-1.263	26
3	GTF2H2C	General transcription factor IIH subunit 2-like protein	Endometrium	-1.089	8
3	GTF2H2C	General transcription factor IIH subunit 2-like protein	Stomach	-1.039	14
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Large Intestine	-1.348	30
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Central Nervous System	-1.265	33
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Head and Neck	-1.252	34
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Pancreas	-1.203	23
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Haematopoietic and Lymphoid	-1.145	14
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Peripheral Nervous System	-1.112	17
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Ovary	-1.109	31
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Breast	-1.081	25
4	PSMD4	26S proteasome non-ATPase regulatory subunit 4	Esophagus	-1.05	26
5	XRCC5	X-ray repair cross-complementing protein 5	Skin	-2.651	4
5	XRCC5	X-ray repair cross-complementing protein 5	Head and Neck	-2.123	34
5	XRCC5	X-ray repair cross-complementing protein 5	Bone	-2.077	12
5	XRCC5	X-ray repair cross-complementing protein 5	Haematopoietic and Lymphoid	-1.983	14
5	XRCC5	X-ray repair cross-complementing protein 5	Esophagus	-1.864	26
5	XRCC5	X-ray repair cross-complementing protein 5	Kidney	-1.83	3
5	XRCC5	X-ray repair cross-complementing protein 5	Central Nervous System	-1.549	33
5	XRCC5	X-ray repair cross-complementing protein 5	Peripheral Nervous System	-1.484	17
5	XRCC5	X-ray repair cross-complementing protein 5	Ovary	-1.468	31
5	XRCC5	X-ray repair cross-complementing protein 5	Lung	-1.441	42
5	XRCC5	X-ray repair cross-complementing protein 5	Stomach	-1.416	14
5	XRCC5	X-ray repair cross-complementing protein 5	Large Intestine	-1.4	30
5	XRCC5	X-ray repair cross-complementing protein 5	Prostate	-1.302	3
5	XRCC5	X-ray repair cross-complementing protein 5	Pancreas	-1.219	23
5	XRCC5	X-ray repair cross-complementing protein 5	Endometrium	-1.136	8
5	XRCC5	X-ray repair cross-complementing protein 5	Breast	-1.027	25