The Ligandable Human Proteome

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Tubulin/FtsZ, GTPase domain

NumberGene NameProtein NamePrimary TissueMedian Essentiality ScoreNumber of Cell Lines
1TUBG2Tubulin gamma-2 chainBone-1.46312
1TUBG2Tubulin gamma-2 chainSkin-1.434
1TUBG2Tubulin gamma-2 chainHead and Neck-1.39934
1TUBG2Tubulin gamma-2 chainHaematopoietic and Lymphoid-1.23114
1TUBG2Tubulin gamma-2 chainLarge Intestine-1.22930
1TUBG2Tubulin gamma-2 chainEsophagus-1.2126
1TUBG2Tubulin gamma-2 chainEndometrium-1.1858
1TUBG2Tubulin gamma-2 chainKidney-1.1223
1TUBG2Tubulin gamma-2 chainCentral Nervous System-1.11833
1TUBG2Tubulin gamma-2 chainLung-1.0942
1TUBG2Tubulin gamma-2 chainOvary-1.00731
1TUBG2Tubulin gamma-2 chainProstate-1.0033
2TUBA1CTubulin alpha-1C chainKidney-3.1783
2TUBA1CTubulin alpha-1C chainLarge Intestine-2.93130
2TUBA1CTubulin alpha-1C chainEsophagus-2.8926
2TUBA1CTubulin alpha-1C chainHead and Neck-2.8134
2TUBA1CTubulin alpha-1C chainSkin-2.7954
2TUBA1CTubulin alpha-1C chainBone-2.66112
2TUBA1CTubulin alpha-1C chainPancreas-2.51723
2TUBA1CTubulin alpha-1C chainLung-2.3842
2TUBA1CTubulin alpha-1C chainBreast-2.22725
2TUBA1CTubulin alpha-1C chainEndometrium-2.1698
2TUBA1CTubulin alpha-1C chainCentral Nervous System-2.14433
2TUBA1CTubulin alpha-1C chainPeripheral Nervous System-2.14217
2TUBA1CTubulin alpha-1C chainOvary-2.08331
2TUBA1CTubulin alpha-1C chainHaematopoietic and Lymphoid-2.05714
2TUBA1CTubulin alpha-1C chainStomach-2.01314
2TUBA1CTubulin alpha-1C chainProstate-1.5983
3TUBA1BTubulin alpha-1B chainSkin-2.8164
3TUBA1BTubulin alpha-1B chainEsophagus-2.42926
3TUBA1BTubulin alpha-1B chainHead and Neck-2.21734
3TUBA1BTubulin alpha-1B chainKidney-2.1513
3TUBA1BTubulin alpha-1B chainBone-2.05212
3TUBA1BTubulin alpha-1B chainProstate-2.0293
3TUBA1BTubulin alpha-1B chainHaematopoietic and Lymphoid-2.00214
3TUBA1BTubulin alpha-1B chainBreast-1.8325
3TUBA1BTubulin alpha-1B chainCentral Nervous System-1.81933
3TUBA1BTubulin alpha-1B chainOvary-1.70431
3TUBA1BTubulin alpha-1B chainStomach-1.63814
3TUBA1BTubulin alpha-1B chainLarge Intestine-1.51930
3TUBA1BTubulin alpha-1B chainLung-1.39142
3TUBA1BTubulin alpha-1B chainEndometrium-1.3238
3TUBA1BTubulin alpha-1B chainPeripheral Nervous System-1.2917
3TUBA1BTubulin alpha-1B chainPancreas-1.21623
4TUBG1Tubulin gamma-1 chainBone-3.37412
4TUBG1Tubulin gamma-1 chainHaematopoietic and Lymphoid-2.59114
4TUBG1Tubulin gamma-1 chainKidney-2.5693
4TUBG1Tubulin gamma-1 chainLarge Intestine-2.55230
4TUBG1Tubulin gamma-1 chainHead and Neck-2.42834
4TUBG1Tubulin gamma-1 chainEsophagus-2.32226
4TUBG1Tubulin gamma-1 chainPeripheral Nervous System-2.16317
4TUBG1Tubulin gamma-1 chainSkin-2.0594
4TUBG1Tubulin gamma-1 chainLung-2.0242
4TUBG1Tubulin gamma-1 chainProstate-1.7073
4TUBG1Tubulin gamma-1 chainCentral Nervous System-1.67133
4TUBG1Tubulin gamma-1 chainStomach-1.66814
4TUBG1Tubulin gamma-1 chainPancreas-1.55823
4TUBG1Tubulin gamma-1 chainOvary-1.51631
4TUBG1Tubulin gamma-1 chainBreast-1.49325
4TUBG1Tubulin gamma-1 chainEndometrium-1.1848
5TUBBTubulin beta chainBone-3.73412
5TUBBTubulin beta chainKidney-3.4053
5TUBBTubulin beta chainHaematopoietic and Lymphoid-3.31814
5TUBBTubulin beta chainSkin-3.1224
5TUBBTubulin beta chainBreast-2.79225
5TUBBTubulin beta chainProstate-2.4213
5TUBBTubulin beta chainCentral Nervous System-2.21533
5TUBBTubulin beta chainEsophagus-226
5TUBBTubulin beta chainOvary-1.75231
5TUBBTubulin beta chainLung-1.74442
5TUBBTubulin beta chainEndometrium-1.728
5TUBBTubulin beta chainPancreas-1.67623
5TUBBTubulin beta chainHead and Neck-1.51634
5TUBBTubulin beta chainStomach-1.43914
5TUBBTubulin beta chainPeripheral Nervous System-1.26917
5TUBBTubulin beta chainLarge Intestine-1.03530