The Ligandable Human Proteome

Heat shock protein 70 family

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	HSPA9	Stress-70 protein, mitochondrial	Bone	-3.671	12
1	HSPA9	Stress-70 protein, mitochondrial	Esophagus	-3.261	26
1	HSPA9	Stress-70 protein, mitochondrial	Head and Neck	-3.195	34
1	HSPA9	Stress-70 protein, mitochondrial	Breast	-3.172	25
1	HSPA9	Stress-70 protein, mitochondrial	Large Intestine	-3.09	30
1	HSPA9	Stress-70 protein, mitochondrial	Central Nervous System	-2.97	33
1	HSPA9	Stress-70 protein, mitochondrial	Skin	-2.964	4
1	HSPA9	Stress-70 protein, mitochondrial	Ovary	-2.934	31
1	HSPA9	Stress-70 protein, mitochondrial	Lung	-2.612	42
1	HSPA9	Stress-70 protein, mitochondrial	Pancreas	-2.558	23
1	HSPA9	Stress-70 protein, mitochondrial	Peripheral Nervous System	-2.448	17
1	HSPA9	Stress-70 protein, mitochondrial	Haematopoietic and Lymphoid	-2.365	14
1	HSPA9	Stress-70 protein, mitochondrial	Endometrium	-2.36	8
1	HSPA9	Stress-70 protein, mitochondrial	Kidney	-2.174	3
1	HSPA9	Stress-70 protein, mitochondrial	Stomach	-2.141	14
1	HSPA9	Stress-70 protein, mitochondrial	Prostate	-1.461	3
2	HSPA8	Heat shock cognate 71 kDa protein	Large Intestine	-3.134	30
2	HSPA8	Heat shock cognate 71 kDa protein	Haematopoietic and Lymphoid	-2.588	14
2	HSPA8	Heat shock cognate 71 kDa protein	Bone	-1.908	12
2	HSPA8	Heat shock cognate 71 kDa protein	Peripheral Nervous System	-1.873	17
2	HSPA8	Heat shock cognate 71 kDa protein	Endometrium	-1.856	8
2	HSPA8	Heat shock cognate 71 kDa protein	Skin	-1.756	4
2	HSPA8	Heat shock cognate 71 kDa protein	Esophagus	-1.563	26
2	HSPA8	Heat shock cognate 71 kDa protein	Stomach	-1.488	14
2	HSPA8	Heat shock cognate 71 kDa protein	Head and Neck	-1.483	34
2	HSPA8	Heat shock cognate 71 kDa protein	Prostate	-1.37	3
2	HSPA8	Heat shock cognate 71 kDa protein	Central Nervous System	-1.36	33
2	HSPA8	Heat shock cognate 71 kDa protein	Ovary	-1.248	31
2	HSPA8	Heat shock cognate 71 kDa protein	Breast	-1.2	25
3	HSPA5	Endoplasmic reticulum chaperone BiP	Haematopoietic and Lymphoid	-1.165	14
3	HSPA5	Endoplasmic reticulum chaperone BiP	Endometrium	-1.059	8
3	HSPA5	Endoplasmic reticulum chaperone BiP	Esophagus	-1.026	26
3	HSPA5	Endoplasmic reticulum chaperone BiP	Head and Neck	-1.025	34