The Ligandable Human Proteome

Tubulin/FtsZ, 2-layer sandwich domain

Number	Gene Name	Protein Name	Primary Tissue	Median Essentiality Score	Number of Cell Lines
1	TUBG2	Tubulin gamma-2 chain	Bone	-1.463	12
1	TUBG2	Tubulin gamma-2 chain	Skin	-1.43	4
1	TUBG2	Tubulin gamma-2 chain	Head and Neck	-1.399	34
1	TUBG2	Tubulin gamma-2 chain	Haematopoietic and Lymphoid	-1.231	14
1	TUBG2	Tubulin gamma-2 chain	Large Intestine	-1.229	30
1	TUBG2	Tubulin gamma-2 chain	Esophagus	-1.21	26
1	TUBG2	Tubulin gamma-2 chain	Endometrium	-1.185	8
1	TUBG2	Tubulin gamma-2 chain	Kidney	-1.122	3
1	TUBG2	Tubulin gamma-2 chain	Central Nervous System	-1.118	33
1	TUBG2	Tubulin gamma-2 chain	Lung	-1.09	42
1	TUBG2	Tubulin gamma-2 chain	Ovary	-1.007	31
1	TUBG2	Tubulin gamma-2 chain	Prostate	-1.003	3
2	TUBA1C	Tubulin alpha-1C chain	Kidney	-3.178	3
2	TUBA1C	Tubulin alpha-1C chain	Large Intestine	-2.931	30
2	TUBA1C	Tubulin alpha-1C chain	Esophagus	-2.89	26
2	TUBA1C	Tubulin alpha-1C chain	Head and Neck	-2.81	34
2	TUBA1C	Tubulin alpha-1C chain	Skin	-2.795	4
2	TUBA1C	Tubulin alpha-1C chain	Bone	-2.661	12
2	TUBA1C	Tubulin alpha-1C chain	Pancreas	-2.517	23
2	TUBA1C	Tubulin alpha-1C chain	Lung	-2.38	42
2	TUBA1C	Tubulin alpha-1C chain	Breast	-2.227	25
2	TUBA1C	Tubulin alpha-1C chain	Endometrium	-2.169	8
2	TUBA1C	Tubulin alpha-1C chain	Central Nervous System	-2.144	33
2	TUBA1C	Tubulin alpha-1C chain	Peripheral Nervous System	-2.142	17
2	TUBA1C	Tubulin alpha-1C chain	Ovary	-2.083	31
2	TUBA1C	Tubulin alpha-1C chain	Haematopoietic and Lymphoid	-2.057	14
2	TUBA1C	Tubulin alpha-1C chain	Stomach	-2.013	14
2	TUBA1C	Tubulin alpha-1C chain	Prostate	-1.598	3
3	TUBA1B	Tubulin alpha-1B chain	Skin	-2.816	4
3	TUBA1B	Tubulin alpha-1B chain	Esophagus	-2.429	26
3	TUBA1B	Tubulin alpha-1B chain	Head and Neck	-2.217	34
3	TUBA1B	Tubulin alpha-1B chain	Kidney	-2.151	3
3	TUBA1B	Tubulin alpha-1B chain	Bone	-2.052	12
3	TUBA1B	Tubulin alpha-1B chain	Prostate	-2.029	3
3	TUBA1B	Tubulin alpha-1B chain	Haematopoietic and Lymphoid	-2.002	14
3	TUBA1B	Tubulin alpha-1B chain	Breast	-1.83	25
3	TUBA1B	Tubulin alpha-1B chain	Central Nervous System	-1.819	33
3	TUBA1B	Tubulin alpha-1B chain	Ovary	-1.704	31
3	TUBA1B	Tubulin alpha-1B chain	Stomach	-1.638	14
3	TUBA1B	Tubulin alpha-1B chain	Large Intestine	-1.519	30
3	TUBA1B	Tubulin alpha-1B chain	Lung	-1.391	42
3	TUBA1B	Tubulin alpha-1B chain	Endometrium	-1.323	8
3	TUBA1B	Tubulin alpha-1B chain	Peripheral Nervous System	-1.29	17
3	TUBA1B	Tubulin alpha-1B chain	Pancreas	-1.216	23
4	TUBG1	Tubulin gamma-1 chain	Bone	-3.374	12
4	TUBG1	Tubulin gamma-1 chain	Haematopoietic and Lymphoid	-2.591	14
4	TUBG1	Tubulin gamma-1 chain	Kidney	-2.569	3
4	TUBG1	Tubulin gamma-1 chain	Large Intestine	-2.552	30
4	TUBG1	Tubulin gamma-1 chain	Head and Neck	-2.428	34
4	TUBG1	Tubulin gamma-1 chain	Esophagus	-2.322	26
4	TUBG1	Tubulin gamma-1 chain	Peripheral Nervous System	-2.163	17
4	TUBG1	Tubulin gamma-1 chain	Skin	-2.059	4
4	TUBG1	Tubulin gamma-1 chain	Lung	-2.02	42
4	TUBG1	Tubulin gamma-1 chain	Prostate	-1.707	3
4	TUBG1	Tubulin gamma-1 chain	Central Nervous System	-1.671	33
4	TUBG1	Tubulin gamma-1 chain	Stomach	-1.668	14
4	TUBG1	Tubulin gamma-1 chain	Pancreas	-1.558	23
4	TUBG1	Tubulin gamma-1 chain	Ovary	-1.516	31
4	TUBG1	Tubulin gamma-1 chain	Breast	-1.493	25
4	TUBG1	Tubulin gamma-1 chain	Endometrium	-1.184	8
5	TUBB	Tubulin beta chain	Bone	-3.734	12
5	TUBB	Tubulin beta chain	Kidney	-3.405	3
5	TUBB	Tubulin beta chain	Haematopoietic and Lymphoid	-3.318	14
5	TUBB	Tubulin beta chain	Skin	-3.122	4
5	TUBB	Tubulin beta chain	Breast	-2.792	25
5	TUBB	Tubulin beta chain	Prostate	-2.421	3
5	TUBB	Tubulin beta chain	Central Nervous System	-2.215	33
5	TUBB	Tubulin beta chain	Esophagus	-2	26
5	TUBB	Tubulin beta chain	Ovary	-1.752	31
5	TUBB	Tubulin beta chain	Lung	-1.744	42
5	TUBB	Tubulin beta chain	Endometrium	-1.72	8
5	TUBB	Tubulin beta chain	Pancreas	-1.676	23
5	TUBB	Tubulin beta chain	Head and Neck	-1.516	34
5	TUBB	Tubulin beta chain	Stomach	-1.439	14
5	TUBB	Tubulin beta chain	Peripheral Nervous System	-1.269	17
5	TUBB	Tubulin beta chain	Large Intestine	-1.035	30