The Ligandable Human Proteome

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Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2

Alpha/beta hydrolase fold-1

IndexLigand NameStructurePDB codeligand desolvation
1mvjligand complex structure of soluble epoxide hydrolase5am497.48
2kwbligand complex structure of soluble epoxide hydrolase5aia95.34
3s0cCrystal structure of soluble epoxide hydrolase in complex with fragment inhibitor3wk594.28
4jqnligand complex structure of soluble epoxide hydrolase5alw93.44
5s0bCrystal structure of soluble epoxide hydrolase in complex with fragment inhibitor3wk693.16
66nzligand complex structure of soluble epoxide hydrolase5am593.06
7w9mCrystal structure of human bifunctional epoxide hydroxylase 2 complexed with C94c4x92.81
82rvCrystal structure of human soluble epoxide hydrolase complexed with 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea4od092.72
96nfligand complex structure of soluble epoxide hydrolase5aki92.72
10r4nligand complex structure of soluble epoxide hydrolase5alg92.24
11s0gCrystal structure of soluble epoxide hydrolase in complex with fragment inhibitor3wka92.22
126n8ligand complex structure of soluble epoxide hydrolase5akl92.21
134a0Structure of soluble epoxide hydrolase in complex with 2-({[2-(adamantan-1-yl)ethyl]amino}methyl)phenol4y2x92.2
14ciuHuman soluble Epoxide Hydrolase- N-cyclohexyl-N'-(4-iodophenyl)urea complex1vj591.94
1524dCrystal Structure of soluble epoxide Hydrolase3koo91.9
16mzlSoluble Epoxide Hydrolase in complex with pyrazole antagonist3otq91.9
17bxvCrystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid.6aum91.88
18fcwligand complex structure of soluble epoxide hydrolase5ald91.71
19zyiCrystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor3pdc91.7
20szcligand complex structure of soluble epoxide hydrolase5fp091.61
21qydligand complex structure of soluble epoxide hydrolase5alp91.52
22aubCrystal structure of soluble epoxide hydrolase in complex with t-AUCB3wke91.04
2334nCrystal Structure of soluble epoxide Hydrolase3i2890.71
24k78ligand complex structure of soluble epoxide hydrolase5ai990.66
25i5tligand complex structure of soluble epoxide hydrolase5am190.51
2649gStructure of soluble epoxide hydrolase in complex with N-[(1-methyl-1H-pyrazol-3-yl)methyl]-2-phenylethanamine4y2j90.38
2733nCrystal Structure of soluble epoxide Hydrolase3i1y90.2
287gmligand complex structure of soluble epoxide hydrolase5alm90.08
295dqligand complex structure of soluble epoxide hydrolase5als90
30aubligand complex structure of soluble epoxide hydrolase5am389.69
312ruCrystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea4ocz89.25
32q3bligand complex structure of soluble epoxide hydrolase5ali89.11
33nc4Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-butyric acid complex1zd388.96
34v2zligand complex structure of soluble epoxide hydrolase5ak588.56
35s82Human soluble epoxide hydrolase in complex with a synthetic inhibitor3ant88.22
364ualigand complex structure of soluble epoxide hydrolase5alh88.21
37i23Crystal structure of human soluble epoxide hydrolase complexed with N-cycloheptyl-1-(mesitylsulfonyl)piperidine-4-carboxamide.4hai88.14
38s94Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative4x6y86.93
39g3qSoluble epoxide hydrolase in complex with talinolol6hgv86.72
40g3tSoluble epoxide hydrolase in complex with 1-(4-((4-(tert-butyl)morpholin-2-yl)methoxy)phenyl)-3-cyclohexylurea6hgx86.28
41a0jligand complex structure of soluble epoxide hydrolase5alo85.41
42e3nSoluble epoxide hydrolase in complex with LK8646fr285.31
431lfSoluble Epoxide Hydrolase complexed with a carboxamide inhibitor4jnc85.17
44nc6Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-hexanoic acid complex1zd484.63
45s74Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative4x6x82.59
46nc7Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-heptanoic acid complex1zd582.35
47s0iCrystal structure of soluble epoxide hydrolase in complex with fragment inhibitor3wkb81.61