The Ligandable Human Proteome

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Glutamate receptor 2

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain

IndexLigand NameStructurePDB codeligand desolvation
1cpwX-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION.1syh99.66
2cpwX-RAY STRUCTURE OF THE Y702F MUTANT OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 2.1 A RESOLUTION.1syi99.54
34zkCrystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (S)-2-amino-3-(3,4-dichloro-5-(5-hydroxypyridin-3-yl)phenyl)propanoic acid at 2.0A resolution5cbr98.34
4m1lThe structure of a mixed glur2 ligand-binding core dimer in complex with (s)-glutamate and the antagonist (s)-ns12092cmo73.96
508wCrystal Structure Analysis of a 6-Amino Quinazolinedione Sulfonamide bound to human GluR23ua866.77
6qsnCrystal Structure Analysis of a Quinazolinedione sulfonamide bound to human GluR2: A Novel Class of Competitive AMPA Receptor Antagonists with Oral Activity3r7x65.25