SGC's E3Hub. An online tool to explore human E3 ligases

comments/feature requests: matthieu.schapira@utoronto.ca

Target Class E1 E2 Multi-subunit E3 ligases Simple E3 ligases NON USP USP Involved in UPS
Any     confidence >=1     confidence >=2     confidence >=3


Options
Sub-Families Essentially in cancer

     Essentiality score lower than
    

Tissue:

Cell Type

Protein Level: High    Medium    Low    Not detected
Reliability: Approved    Enhanced    Supported    Uncertain
High    Medium    Low
in    of normal tissues
Reliability: Approved    Enhanced    Supported    Uncertain

Cancer Type

Protein Level: High    Medium    Low    Not detected
High    Medium    Low
in    of tumors




Most symbols on the trees are clickable.
Trees are generated with this script.
| Full Length FASTA File | Full Length Alignment File | Domain Alignment File
The phylogeny outlined in the tree is derived from a CLUSTALW multiple sequence alignment of the full-length sequence of the default Swiss-Prot variant.