The Ligandable Human Proteome

Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2

Index	Ligand Name	Structure	PDB code	Compound Potency nM
1	2ru	Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea	4ocz	0.66
2	2rv	Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea	4od0	0.91
3	aub	Crystal structure of soluble epoxide hydrolase in complex with t-AUCB	3wke	1.3
4	s74	Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative	4x6x	2.3
5	1lf	Soluble Epoxide Hydrolase complexed with a carboxamide inhibitor	4jnc	3
6	i5t	ligand complex structure of soluble epoxide hydrolase	5am1	3
7	aub	ligand complex structure of soluble epoxide hydrolase	5am3	5
8	34n	Crystal Structure of soluble epoxide Hydrolase	3i28	6
9	33n	Crystal Structure of soluble epoxide Hydrolase	3i1y	7
10	i23	Crystal structure of human soluble epoxide hydrolase complexed with N-cycloheptyl-1-(mesitylsulfonyl)piperidine-4-carboxamide.	4hai	7.9
11	s82	Human soluble epoxide hydrolase in complex with a synthetic inhibitor	3ant	8.5
12	24d	Crystal Structure of soluble epoxide Hydrolase	3koo	15
13	szc	ligand complex structure of soluble epoxide hydrolase	5fp0	17
14	5dq	ligand complex structure of soluble epoxide hydrolase	5als	19
15	s94	Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative	4x6y	19.1
16	r4n	ligand complex structure of soluble epoxide hydrolase	5alg	30
17	zyi	Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor	3pdc	32
18	mzl	Soluble Epoxide Hydrolase in complex with pyrazole antagonist	3otq	41
19	q3b	ligand complex structure of soluble epoxide hydrolase	5ali	86
20	4ua	ligand complex structure of soluble epoxide hydrolase	5alh	86
21	v2z	ligand complex structure of soluble epoxide hydrolase	5ak5	86
22	6n8	ligand complex structure of soluble epoxide hydrolase	5akl	86
23	qyd	ligand complex structure of soluble epoxide hydrolase	5alp	86
24	mvj	ligand complex structure of soluble epoxide hydrolase	5am4	113
25	ciu	Human soluble Epoxide Hydrolase- N-cyclohexyl-N'-(4-iodophenyl)urea complex	1vj5	120
26	k78	ligand complex structure of soluble epoxide hydrolase	5ai9	244
27	7gm	ligand complex structure of soluble epoxide hydrolase	5alm	294
28	4a0	Structure of soluble epoxide hydrolase in complex with 2-({[2-(adamantan-1-yl)ethyl]amino}methyl)phenol	4y2x	510
29	a0j	ligand complex structure of soluble epoxide hydrolase	5alo	738
30	6nf	ligand complex structure of soluble epoxide hydrolase	5aki	754
31	fcw	ligand complex structure of soluble epoxide hydrolase	5ald	1080
32	6nz	ligand complex structure of soluble epoxide hydrolase	5am5	1820
33	kwb	ligand complex structure of soluble epoxide hydrolase	5aia	6268
34	s0b	Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor	3wk6	6300
35	jqn	ligand complex structure of soluble epoxide hydrolase	5alw	7050
36	nc7	Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-heptanoic acid complex	1zd5	1.34e+004
37	s0c	Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor	3wk5	1.5e+004
38	s0g	Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor	3wka	2.9e+004
39	s0i	Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor	3wkb	6.1e+004
40	nc6	Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-hexanoic acid complex	1zd4	2.53e+005
41	nc4	Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-butyric acid complex	1zd3	5e+005
42	49g	Structure of soluble epoxide hydrolase in complex with N-[(1-methyl-1H-pyrazol-3-yl)methyl]-2-phenylethanamine	4y2j	8e+005