Index | Ligand Name | Structure | PDB code | Compound Potency nM |
---|---|---|---|---|
1 | wfe | Crystal structure of Akt-1-inhibitor complexes | 3mvh | 0.5 |
2 | 0xz | PKB alpha in complex with AZD5363 | 4gv1 | 3 |
3 | smy | Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors | 3ow4 | 22 |
4 | sm9 | Spirocyclic sulfonamides as AKT inhibitors | 3qkm | 38 |
5 | xfe | Crystal structure of Akt-1-inhibitor complexes | 3mv5 | 180 |