Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | sm5 | Pyrazole-based inhibitors of B-Raf kinase | 3d4q | 0.03 |
2 | 215 | Structure of the B-Raf kinase domain bound to SB-590885 | 2fb8 | 0.16 |
3 | 8en | Crystals Structure of B-Raf kinase domain in complex with an Imidazopyridinyl benzamide inhibitor | 6b8u | 0.2 |
4 | fni | Human B-Raf Kinase in Complex with a Non-Oxime Furopyridine Inhibitor | 3ppk | 1.4 |
5 | fp3 | Crystal Structure of Human B-Raf Kinase Domain in Complex with a Non-Oxime Furopyridine Inhibitor | 3prf | 1.4 |
6 | l1e | B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor | 3idp | 1.6 |
7 | 1su | Crystal Structure of Human B-raf bound to a DFG-out Inhibitor TAK-632 | 4ksp | 1.6 |
8 | p06 | B-RAF in complex with Dabrafenib | 5csw | 4 |
9 | 904 | B-Raf Kinase V600E oncogenic mutant in complex with PLX7904 | 4xv1 | 4.2 |
10 | p06 | B-Raf Kinase V600E oncogenic mutant in complex with Dabrafenib | 4xv2 | 5.4 |
11 | 54j | CRYSTAL STRUCTURE OF B-RAF IN COMPLEX WITH BI 882370 | 5csx | 6 |
12 | p02 | B-Raf Kinase V600E oncogenic mutant in complex with PLX7922 | 4xv3 | 12 |
13 | bax | The complex of wild type B-RAF and BAY439006. | 1uwh | 22 |
14 | 831 | The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor | 3ii5 | 24 |
15 | 032 | B-Raf Kinase V600E oncogenic mutant in complex with PLX4032 | 3og7 | 31 |
16 | 0t2 | Crystal Structure of Human Kinase Domain of B-raf with a DFG-out Inhibitor | 4fc0 | 69 |
17 | 5xj | B-Raf wild-type kinase domain in complex with a purinylpyridinylamino-based inhibitor | 5fd2 | 90 |
18 | 324 | B-Raf Kinase in Complex with PLX4720 | 3c4c | 160 |
19 | 6n9 | BRAFV600E Kinase Domain In Complex with Chemically Linked Vemurafenib Inhibitor VEM-6-VEM | 5jrq | 169 |
20 | 1oo | B-Raf Kinase domain in complex with PLX5568 | 4xv9 | 190 |