Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | krl | cFMS Tyrosine kinase in complex with 5-Cyano-furan-2-carboxylic acid [4-(4-methyl-piperazin-1-yl)-2-piperidin-1-yl-phenyl]-amide | 3krl | 0.8 |
2 | krj | cFMS tyrosine kinase in complex with 4-Cyano-1H-imidazole-2-carboxylic acid (2-cyclohex-1-enyl-4-piperidin-4-yl-phenyl)-amide | 3krj | 1.1 |
3 | 8c5 | cFMS tyrosine kinase in complex with a pyridopyrimidinone inhibitor | 3dpk | 4.1 |
4 | ixh | cFMS tyrosine kinase (tie2 KID) in complex with a pyrimidinopyridone inhibitor | 3bea | 7 |
5 | 5cn | cFMS tyrosine kinase (FGF KID) in complex with an arylamide inhibitor | 2i0y | 24 |
6 | bdy | Inhibitor Bound to A DFG-In structure of the Kinase Domain of CSF-1R | 3lcd | 40 |
7 | 64m | Crystal structure of FMS kinase domain with a small molecular inhibitor, PLX647-OME | 4hw7 | 62 |
8 | 6c3 | c-FMS tyrosine kinase in complex with a quinolone inhibitor | 2i0v | 160 |