The Ligandable Human Proteome

Index	Ligand Name	Structure	PDB code	Compound Potency nM
1	8cg	Crystal structure of IRAK4 in complex with compound 30	5uiu	0.2
2	xpy	Crystal structure of IRAK4 kinase domain with inhibitor	4y73	0.3
3	8cd	Crystal structure of IRAK4 in complex with compound 14	5uit	4.6
4	6r1	IRAK4 in complex with Compound 28	5k76	5
5	9ys	CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 9)	5w85	10
6	4gf	Irak4-inhibitor co-structure	4yp8	13
7	4s3	Irak4-inhibitor co-structure	4ztn	19
8	4s2	Irak4-inhibitor co-structure	4ztm	25
9	6ye	Irak4-inhibitor co-structure	5kx8	38
10	8by	Crystal structure of IRAK4 in complex with compound 11	5uir	71.9
11	76q	Irak4 kinase - compound 1 co-structure	5t1s	84
12	8c1	Crystal structure of IRAK4 in complex with compound 12	5uis	146
13	9yy	CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 4)	5w84	360
14	4s1	Irak4-inhibitor co-structure	4ztl	1200
15	42p	Irak4-inhibitor co-structure	4xs2	1520
16	4gd	Irak4-inhibitor co-structure	4yo6	2200