Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | 1j2 | Crystal structure of JNK1 in complex with JIP1 peptide and 4-{4-[4-(4-Methanesulfonyl-piperidin-1-yl)-indol-1-yl]-pyrimidin-2-ylamino}-cyclohexan | 4izy | 3 |
2 | 1bk | Crystal structure of JNK1 in complex with JIP1 peptide and 4-{4-[4-(3-Methanesulfonyl-propoxy)-indazol-1-yl]-pyrimidin-2-ylamino}-cyclohexan | 4hyu | 6.2 |
3 | 1bj | Crystal structure of JNK1 in complex with JIP1 peptide and 4-(4-Indazol-1-yl-pyrimidin-2-ylamino)-cyclohexan | 4hys | 55 |
4 | 1v5 | Co-crystal Structure of JNK1 and AX13587 | 4l7f | 160 |
5 | 893 | Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun NH2-terminal Kinase Inhibitors | 2h96 | 230 |
6 | aq2 | Human Jnk1alpha kinase with 4-phenyl-7-azaindole IKK2 inhibitor. | 4awi | 1000 |
7 | 38z | Structure of human JNK1 in complex with SCH772984 and the AMPPNP-hydrolysed triphosphate revealing the second type-I binding mode | 4qtd | 1080 |
8 | myu | Structural and functional analysis of quercetagetin, a natural JNK1 inhibitor | 3v3v | 4600 |
9 | gs7 | Jnk1 complexed with a bis-anilino-pyrrolopyrimidine inhibitor. | 3elj | 5000 |