| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | 0f0 | Discovery of potent and selective covalent inhibitors of JNK | 3v6s | 0.75 |
| 2 | 3nl | Design and Synthesis of Highly Potent and Isoform Selective JNK3 Inhibitors: SAR Studies on Aminopyrazole Derivatives | 4whz | 1 |
| 3 | 880 | THE STRUCTURE OF JNK3 IN COMPLEX WITH AN IMIDAZOLE-PYRIMIDINE INHIBITOR | 4z9l | 1.6 |
| 4 | bz9 | Crystal Structure of human JNK3 complexed with N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine | 3da6 | 2 |
| 5 | aiz | inhibitor complex of JNK3 | 2b1p | 3 |
| 6 | kbi | Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor | 3tti | 6 |
| 7 | 34i | Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration | 3rtp | 7 |
| 8 | 984 | Crystal structure of JNK3 in complex with an imidazole-pyrimidine inhibitor | 1pmn | 7.1 |
| 9 | 46c | Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor | 2zdt | 9.6 |
| 10 | 4f2 | Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors | 4y46 | 11 |
| 11 | 519 | Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) inhibitors | 4y5h | 15 |
| 12 | 932 | Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor | 3ptg | 25 |
| 13 | 3wh | The MAP kinase JNK3 as target for halogen bonding | 4x21 | 36 |
| 14 | j07 | Synthesis and SAR of Aminopyrimidines as Novel c-Jun N-Terminal Kinase (JNK) Inhibitors | 2p33 | 57 |
| 15 | 3hn | JNK2/3 in complex with 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide | 4w4x | 102.8 |
| 16 | 3h8 | JNK2/3 in complex with 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide | 4w4v | 115 |
| 17 | 255 | c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor | 2r9s | 150 |
| 18 | jk3 | JNK3 bound to piperazine amide inhibitor, SR2774. | 3fv8 | 160 |
| 19 | jbi | Crystal Structure of JNK3 complexed with CC-359, a JNK inhibitor for the prevention of ischemia-reperfusion injury | 3ttj | 210 |
| 20 | jnk | Inhibitor complex of JNK3 | 2exc | 235 |
| 21 | snb | Crystal structure of human Jnk3 complexed with a 1-aryl-3,4- dihydroisoquinoline inhibitor | 2waj | 398 |
| 22 | 3el | Crystal structure of human JNK3 in complex with a benzenesulfonamide inhibitor. | 4u79 | 400 |
| 23 | 738 | Crystal structure of human JNK3 complexed with N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide | 2o2u | 400 |
| 24 | j72 | JNK-3 bound to (Z)-5-fluoro-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)indolin-2-one | 3g90 | 440 |
| 25 | cqq | Discovery of potent and selective covalent inhibitors of JNK | 3v6r | 709 |
| 26 | j67 | JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-styrylindolin-2-one | 3g9l | 740 |
| 27 | j88 | JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-phenylindolin-2-one | 3g9n | 1800 |
| 28 | syy | Design and Synthesis of Disubstituted Thiophene and Thiazole Based Inhibitors of JNK for the Treatment of Neurodegenerative Diseases | 3oxi | 2200 |
| 29 | jno | IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding | 3cgo | 3000 |
| 30 | c0m | Crystal structure of human JNK3 complexed with N-{3-cyano-6-[3-(1-piperidinyl)propanoyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl}-1-naphthalenecarboxamide | 2o0u | 3200 |