| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | jup | NEK2-EDE bound to CCT248662 | 4a4x | 59 |
| 2 | ggy | Nek2 bound to hybrid compound 21 | 4afe | 73 |
| 3 | wgz | Structure of NEK2 bound to CCT | 2xnm | 160 |
| 4 | 7gg | Nek2 bound to arylaminopurine 71 | 5m55 | 240 |
| 5 | wcx | Structure of Nek2 bound to CCT244858 | 2xnp | 360 |
| 6 | 7gj | Nek2 bound to arylaminopurine inhibitor 11 | 5m53 | 620 |
| 7 | bx1 | Structure of Nek2 bound to aminopyrazine compound 2 | 2xkf | 870 |
| 8 | ed8 | Structure of Nek2 bound to CCT243779 | 2xno | 1180 |
| 9 | 30e | Structure of Nek2 bound to aminopyrazine compound 23 | 2xk7 | 1500 |
| 10 | eqh | Structure of Nek2 bound to aminopyrazine compound 36 | 2xk6 | 1600 |
| 11 | xk3 | Structure of Nek2 bound to Aminopyrazine compound 35 | 2xk3 | 2100 |
| 12 | t3m | Structure of Nek2 bound to aminopyrazine compound 12 | 2xkd | 2300 |
| 13 | 5r1 | Structure of Nek2 bound to aminopyrazine compound 15 | 2xk8 | 2400 |
| 14 | 4vq | Structure of Nek2 bound to aminopyrazine compound 14 | 2xkc | 2600 |
| 15 | wi2 | Structure of Nek2 bound to Aminipyrazine Compound 5 | 2xke | 4200 |
| 16 | 4sp | Nek2 bound to arylaminopurine 6 | 5m57 | 1.2e+004 |
| 17 | ol2 | Structure of Nek2 bound to aminopyrazine compound 17 | 2xk4 | 1.69e+004 |
| 18 | nu6 | Nek2 bound to arylaminopurine compound 8 | 5m51 | 1.9e+004 |
| 19 | 430 | Structure of Nek2 bound to CCT242430 | 2xnn | 5e+004 |