The Ligandable Human Proteome


Proto-oncogene tyrosine-protein kinase receptor Ret

Protein kinase domain

IndexLigand NameStructurePDB codeCompound Potency nM
1dtqThe Discovery of 2-Substituted Phenol Quinazolines as Potent and Selective RET Kinase Inhibitors5amn4.5
2zd6Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor ZD64742ivu375
3adnCrystal Structure of oncogenic RET tyrosine kinase M918T bound to adenosine4cki1100
4adnCrystal structure of RET tyrosine kinase domain bound to adenosine4ckj1.43e+004