The Ligandable Human Proteome

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Receptor-interacting serine/threonine-protein kinase 2

Protein kinase domain

IndexLigand NameStructurePDB codeCompound Potency nM
19xaIdentification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.5w5o8
2sb2RIP2 Kinase Catalytic Domain (1 - 310) complex with SB-2035805ar4200
3sr8RIP2 Kinase Catalytic Domain (1 - 310) complex with Biaryl Urea5ar7320
4iq7RIP2 Kinase Catalytic Domain (1 - 310) complex with Benzimidazole5ar5500
59wsIdentification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases5w5j1500