Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | 8wk | Crystal structure of USP7 in complex with the non-covalent inhibitor, FT671 | 5nge | 65 |
2 | 9qd | Structure of DUB complex | 5vs6 | 104 |
3 | 8qq | Crystal structure of USP7 in complex with a potent, selective and reversible small-molecule inhibitor | 5n9t | 220 |
4 | 8jm | USP7 in complex with GNE6640 (4-(2-amino-4-ethyl-5-(1H-indazol-5-yl)pyridin-3-yl)phenol) | 5uqv | 430 |
5 | 8jp | USP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide) | 5uqx | 610 |
6 | 8rn | Crystal structure of USP7 in complex with a potent, selective and reversible small-molecule inhibitor | 5n9r | 2600 |
7 | 9qa | Structure of DUB complex | 5vsb | 7614 |
8 | 8wn | Crystal structure of USP7 in complex with the covalent inhibitor, FT827 | 5ngf | 7800 |
9 | ajj | USP7 in complex with Cpd2 (4-(3-(1-methylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl)phenol) | 5whc | 1.2e+004 |