Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | whh | Crystal structure of the catalytic domain of MMP-13 complexed with 4-(2-((6-fluoro-2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydroquinazolin-5-yl)oxy)ethyl)benzoic acid | 3wv1 | 0.0039 |
2 | 3kr | Crystal structure of MMP-13 in complex with SC-78080 | 3kry | 0.1 |
3 | cbp | CRYSTAL STRUCTURE OF COLLAGENASE-3 (MMP-13) COMPLEXED TO A DIPHENYL-ETHER SULPHONE BASED HYDROXAMIC ACID | 456c | 0.17 |
4 | 24f | Crystal Structure of MMP-13 Complexed with Inhibitor 24f | 3elm | 0.19 |
5 | wnn | Crystal structure of the catalytic domain of MMP-13 complexed with 4-oxo-N-(3-(2-(1H-1,2,4-triazol-3-ylsulfanyl)ethoxy)benzyl)-3,4-dihydroquinazoline-2-carboxamide | 5b5p | 0.2 |
6 | rs1 | COLLAGENASE-3 (MMP-13) COMPLEXED TO A SULPHONE-BASED HYDROXAMIC ACID | 830c | 0.52 |
7 | gg1 | MMP13 Catalytic Domain Complexed with 4-{[1-methyl-2,4-dioxo-6-(3-phenylprop-1-yn-1-yl)-1,4-dihydroquinazolin-3(2H)-yl]methyl}benzoic acid | 2ozr | 0.67 |
8 | pfd | Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor | 1you | 0.87 |
9 | 4uf | X-RAY Co-structure of MMP-13 with 4-[({5-[2-(ethoxycarbonyl)-1H-indol-5-yl]-1-methyl-1H-pyrazol-3-yl}formamido)methyl]benzoate | 5bpa | 1 |
10 | 033 | Crystal structure of the catalytic domain of MMP-13 complexed with WAY-033 | 1ztq | 1.3 |
11 | 8om | Matrix metalloproteinase-13 complexed with selective inhibitor compound (S)-10a | 5uwk | 2.3 |
12 | e41 | MMP-13 complexed with 2-Napthylsulfonamide hydroxamic acid inhibitor | 3zxh | 3 |
13 | az6 | Mmp13 in complex with a piperazine hydantoin ligand | 4jpa | 3.3 |
14 | 3ek | Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound | 3kek | 4.4 |
15 | la3 | Crystal Structure of Human MMP-13 complexed with an Amino-2-indanol compound | 3ljz | 7.3 |
16 | pb4 | Matrix metalloproteinase-13 complexed with non-zinc binding inhibitor | 1xud | 8 |
17 | 8oj | Matrix metalloproteinase-13 complexed with selective inhibitor compound (S)-17a | 5uwl | 9.4 |
18 | wgg | Crystal structure of the catalytic domain of MMP-13 complexed with N-(3-methoxybenzyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide | 3wv2 | 12 |
19 | wll | Crystal structure of the catalytic domain of MMP-13 complexed with N-(3-methoxybenzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxamide | 3wv3 | 24 |
20 | 3w5 | MMP13 IN COMPLEX WITH A NOVEL SELECTIVE NON ZINC BINDING INHIBITOR CMPD22 | 4a7b | 39.8 |
21 | 3ke | Crystal Structure of Human MMP-13 complexed with a phenyl-2H-tetrazole compound | 3kec | 58 |
22 | pb3 | Matrix metalloproteinase-13 complexed with non-zinc binding inhibitor | 1xuc | 72 |
23 | 3ej | Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound | 3kej | 75.9 |
24 | 5el | MMP13 in complex with a novel selective non zinc binding inhibitor | 2yig | 79.4 |
25 | 732 | MMP-13 in complex with a non zinc-chelating inhibitor | 3i7g | 430 |
26 | 518 | MMP-13 in complex with a non zinc-chelating inhibitor | 3i7i | 620 |
27 | 347 | Crystal structure of the catalytic domain of MMP-13 complexed with WAY-344 | 2pjt | 860 |
28 | pb5 | Matrix metalloproteinase-13 complexed with non-zinc binding inhibitor | 1xur | 6600 |