The Ligandable Human Proteome

cAMP-specific 3',5'-cyclic phosphodiesterase 4B

3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

Index	Ligand Name	Structure	PDB code	Compound Potency nM
1	066	Catalytic domain of human phosphodiesterase 4B2B in complex with a quinoline inhibitor	3gwt	0.00794
2	pil	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Piclamilast	1xm4	0.041
3	zg2	Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor	3o57	0.0794
4	rof	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Roflumilast	1xmu	0.84
5	20a	Crystal structure of PDE4B catalytic domain in complex with a pyrazolopyridine inhibitor	3d3p	3.16
6	sk4	Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with a Quinoline Inhibitor	3frg	3.98
7	z72	Catalytic Domain of Human Phosphodiesterase 4B in Complex with A Coumarin-Based Inhibitor	3ly2	5
8	qpc	Crystal structure of phosphodiesterase 4B in complex with compound 10f	3wd9	8.3
9	nvw	Crystal structure of phosphodiesterase 4B in complex with compound 31e	3w5e	11
10	cio	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Cilomilast	1xlx	25
11	19t	Selective Inhibition of the Catalytic Domain Of Human Phosphodiesterase 4B With A-33	4myq	32
12	rol	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R)-Rolipram	1xmy	50.12
13	hbt	Catalytic domain of human phosphodiesterase 4B2B in complex with a tetrahydrobenzothiophene inhibitor	3hmv	50.12
14	2o5	PDE4 catalytic domain	4nw7	237
15	rol	Crystal structure of PDE4B2B complexed with Rolipram (R & S)	1ro6	350
16	rol	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R,S)-Rolipram	1xn0	570
17	fil	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Filaminast	1xlz	960
18	vdn	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Vardenafil	1xot	3800
19	via	Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Sildenafil	1xos	2e+004