The Ligandable Human Proteome

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High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

IndexLigand NameStructurePDB codeCompound Potency nM
135ophosphodiesterase-9A in complex with inhibitor WYQ-C36D4qge0.5
2wtcHuman phosphodiesterase 9 in complex with inhibitor3jsi2.1
30wfHuman pde9 in complex with selective compound4g2j11
449dCrystal structure of phosphodiesterase 9 in complex with (S)-C334y8c11
5luoCrystal structure of the PDE9A catalytic domain in complex with inhibitor 284gh621
6pdbCrystal structure of the PDE9A catalytic domain in complex with (R)-BAY73-66913k3e22
70wlHuman PDE9 in complex with selective compound4g2l32
8jarHuman PDE9 in complex with selective inhibitor3jsw66
9byeCrystal structure of the PDE9A catalytic domain in complex with (S)-BAY73-66913k3h88
10ibmCrystal structure of PDE9A(Q453E) in complex with IBMX3qi41.172e+005
11pdbCrystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-66913qi31.642e+005
12ibmCrystal structure of PDE9 in complex with IBMX2hd15e+005